zgc:86598 zgc:86598 [Danio rerio (zebrafish)] - Gene

Summary

Official Symbol: zgc:86598provided by ZNC
Official Full Name: zgc:86598provided by ZNC
Primary source: ZFIN:ZDB-GENE-040625-181
See related: Ensembl:ENSDARG00000014222 AllianceGenome:ZFIN:ZDB-GENE-040625-181
Gene type: protein coding
RefSeq status: PROVISIONAL
Organism: Danio rerio
Lineage: Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Actinopterygii; Neopterygii; Teleostei; Ostariophysi; Cypriniformes; Danionidae; Danioninae; Danio
Also known as: ck2a1; im:6891713; si:ch211-133n4.5
Summary: Predicted to enable protein serine/threonine kinase activity. Predicted to be involved in peptidyl-serine phosphorylation; peptidyl-threonine phosphorylation; and regulation of cell cycle. Predicted to act upstream of or within protein phosphorylation. Predicted to be part of protein kinase CK2 complex. Predicted to be active in cytosol and nucleus. Orthologous to human CSNK2A1 (casein kinase 2 alpha 1). [provided by Alliance of Genome Resources, Apr 2022]
Orthologs: all
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Genomic context

Location:: chromosome: 19

Exon count:: 14

Annotation release	Status	Assembly	Chr	Location
106	current	GRCz11 (GCF_000002035.6)	19	NC_007130.7 (3206268..3232710)
105	previous assembly	GRCz10 (GCF_000002035.5)	19	NC_007130.6 (3265370..3291812)

Chromosome 19 - NC_007130.7 Genomic Context describing neighboring genes

Genomic regions, transcripts, and products

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Genomic Sequence:

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Expression

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See details

Project title: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
Description: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
BioProject: PRJEB1986
Analysis date: Fri Dec 8 19:48:10 2017

Bibliography

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GeneRIFs: Gene References Into Functions

What's a GeneRIF?

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General gene information

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Gene Ontology Provided by ZFIN

Function	Evidence Code	Pubs
enables ATP binding	IEA Inferred from Electronic Annotation more info
enables kinase activity	IEA Inferred from Electronic Annotation more info
enables nucleotide binding	IEA Inferred from Electronic Annotation more info
enables protein kinase activity	IEA Inferred from Electronic Annotation more info
enables protein serine/threonine kinase activity	IBA Inferred from Biological aspect of Ancestor more info
enables protein serine/threonine kinase activity	IEA Inferred from Electronic Annotation more info
enables transferase activity	IEA Inferred from Electronic Annotation more info

Process	Evidence Code	Pubs
involved_in peptidyl-serine phosphorylation	IBA Inferred from Biological aspect of Ancestor more info
involved_in peptidyl-threonine phosphorylation	IBA Inferred from Biological aspect of Ancestor more info
acts_upstream_of_or_within phosphorylation	IEA Inferred from Electronic Annotation more info
involved_in regulation of cell cycle	IBA Inferred from Biological aspect of Ancestor more info

Component	Evidence Code	Pubs
is_active_in cytosol	IBA Inferred from Biological aspect of Ancestor more info
is_active_in nucleus	IBA Inferred from Biological aspect of Ancestor more info
part_of protein kinase CK2 complex	IBA Inferred from Biological aspect of Ancestor more info

General protein information

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Preferred Names: STKc_CK2_alpha domain-containing protein; casein kinase II alpha 1 subunit

Names: casein kinase 2 alpha 1

NP_001002164.1

EC 2.7.11.1

XP_005159385.1

EC 2.7.11.1

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

NM_001002164.1 → NP_001002164.1 STKc_CK2_alpha domain-containing protein

See identical proteins and their annotated locations for NP_001002164.1

Status: PROVISIONAL

Source sequence(s)

BC071303

UniProtKB/TrEMBL

A0A2R8Q9K8, F6NIQ6, Q6IQV0

Related

ENSDARP00000024748.9, ENSDART00000020344.10

Conserved Domains (2) summary

cd14132
Location:20 → 325

STKc_CK2_alpha; Catalytic subunit (alpha) of the Serine/Threonine Kinase, Casein Kinase 2

pfam00069
Location:39 → 324

Pkinase; Protein kinase domain

RefSeqs of Annotated Genomes: Danio rerio Annotation Release 106 details...

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCz11 Primary Assembly

Genomic

NC_007130.7 Reference GRCz11 Primary Assembly

Range

3206268..3232710

Download

GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

XM_005159328.3 → XP_005159385.1 casein kinase II alpha 1 subunit isoform X1

UniProtKB/TrEMBL

A0A8M2B6B1

Conserved Domains (3) summary

cd14132
Location:20 → 325

STKc_CK2_alpha; Catalytic subunit (alpha) of the Serine/Threonine Kinase, Casein Kinase 2

pfam00069
Location:39 → 324

Pkinase; Protein kinase domain

pfam11825
Location:334 → 379

Nuc_recep-AF1; Nuclear/hormone receptor activator site AF-1