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    Tex35 testis expressed 35 [ Mus musculus (house mouse) ]

    Gene ID: 73435, updated on 3-Apr-2024

    Summary

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    Official Symbol
    Tex35provided by MGI
    Official Full Name
    testis expressed 35provided by MGI
    Primary source
    MGI:MGI:1920685
    See related
    Ensembl:ENSMUSG00000026592 AllianceGenome:MGI:1920685
    Gene type
    protein coding
    RefSeq status
    VALIDATED
    Organism
    Mus musculus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
    Also known as
    1700057K13Rik
    Summary
    Located in nucleus. Orthologous to human TEX35 (testis expressed 35). [provided by Alliance of Genome Resources, Apr 2022]
    Expression
    Restricted expression toward testis adult (RPKM 77.3) See more
    Orthologs
    human all
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    Genomic context

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    Location:
    1 H1; 1 67.97 cM
    Exon count:
    13
    Annotation release Status Assembly Chr Location
    RS_2024_02 current GRCm39 (GCF_000001635.27) 1 NC_000067.7 (156926711..156938506, complement)
    108.20200622 previous assembly GRCm38.p6 (GCF_000001635.26) 1 NC_000067.6 (157099141..157108680, complement)

    Chromosome 1 - NC_000067.7Genomic Context describing neighboring genes Neighboring gene STARR-seq mESC enhancer starr_02758 Neighboring gene STARR-positive B cell enhancer ABC_E5828 Neighboring gene STARR-positive B cell enhancer ABC_E4364 Neighboring gene STARR-seq mESC enhancer starr_02759 Neighboring gene STARR-positive B cell enhancer ABC_E2573 Neighboring gene STARR-positive B cell enhancer ABC_E3318 Neighboring gene predicted gene, 39685 Neighboring gene STARR-positive B cell enhancer ABC_E1569 Neighboring gene STARR-positive B cell enhancer mm9_chr1:158957909-158958210 Neighboring gene STARR-seq mESC enhancer starr_02761 Neighboring gene STARR-positive B cell enhancer ABC_E7762 Neighboring gene STARR-positive B cell enhancer ABC_E1232 Neighboring gene STARR-seq mESC enhancer starr_02762 Neighboring gene STARR-positive B cell enhancer ABC_E7763 Neighboring gene predicted gene, 30568 Neighboring gene predicted gene, 30694 Neighboring gene RAS protein activator like 2 Neighboring gene predicted gene, 51654

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Expression

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    • Project title: Mouse ENCODE transcriptome data
    • Description: RNA profiling data sets generated by the Mouse ENCODE project.
    • BioProject: PRJNA66167
    • Publication: PMID 25409824
    • Analysis date: n/a

    Bibliography

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    Related articles in PubMed

    1. Identification and characteristics of a novel testis-specific gene, Tsc24, in human and mice. Tang A, et al. Biol Pharm Bull, 2006 Nov. PMID 17077512
    2. CRISPR/Cas9-mediated genome editing reveals 30 testis-enriched genes dispensable for male fertility in mice†. Lu Y, et al. Biol Reprod, 2019 Aug 1. PMID 31201419, Free PMC Article
    3. Database resources of the National Center for Biotechnology Information. Wheeler DL, et al. Nucleic Acids Res, 2001 Jan 1. PMID 11125038, Free PMC Article
    4. A conditional knockout resource for the genome-wide study of mouse gene function. Skarnes WC, et al. Nature, 2011 Jun 15. PMID 21677750, Free PMC Article
    5. Wnk1 kinase deficiency lowers blood pressure in mice: a gene-trap screen to identify potential targets for therapeutic intervention. Zambrowicz BP, et al. Proc Natl Acad Sci U S A, 2003 Nov 25. PMID 14610273, Free PMC Article

    See all (15) citations in PubMed

    GeneRIFs: Gene References Into Functions

    Variation

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    Alleles

    Alleles of this type are documented at Mouse Genome Informatics  (MGI)

    General gene information

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    Markers

    Homology

    Clone Names

    • MGC118391, MGC144290

    Gene Ontology Provided by MGI

    Function Evidence Code Pubs
    enables molecular_function ND
    No biological Data available
    more info
    		  
    Process Evidence Code Pubs
    involved_in biological_process ND
    No biological Data available
    more info
    		  
    Component Evidence Code Pubs
    located_in microtubule cytoskeleton ISO
    Inferred from Sequence Orthology
    more info
    		  
    is_active_in nucleus IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    located_in nucleus IDA
    Inferred from Direct Assay
    more info
    		 PubMed 

    General protein information

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    Preferred Names
    testis-expressed protein 35
    Names
    testis-expressed sequence 35 protein
    testis-specific conserved protein of 24 kDa

    NCBI Reference Sequences (RefSeq)

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    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001305059.1 → NP_001291988.1  testis-expressed protein 35 isoform 2

      See identical proteins and their annotated locations for NP_001291988.1

      Status: VALIDATED

      Source sequence(s)
      AK006825, CJ232085
      Consensus CDS
      CCDS78718.1
      UniProtKB/Swiss-Prot
      Q14BK3, Q4KKY9, Q9D9J9
      UniProtKB/TrEMBL
      A0A0R4J070
      Related
      ENSMUSP00000027884.7, ENSMUST00000027884.13
      Conserved Domains (1) summary
      pfam15079
      Location:1 → 194
      Tsc35; Testis-specific protein 35

    2. NM_001305061.1 → NP_001291990.1  testis-expressed protein 35 isoform 3

      See identical proteins and their annotated locations for NP_001291990.1

      Status: VALIDATED

      Source sequence(s)
      AC119220, AK006825, BY706810, CJ232085
      Consensus CDS
      CCDS78716.1
      UniProtKB/Swiss-Prot
      Q14BK3, Q4KKY9, Q9D9J9
      UniProtKB/TrEMBL
      D3Z4U7
      Conserved Domains (1) summary
      pfam15079
      Location:1 → 172
      Tsc35; Testis-specific protein 35

    3. NM_001305062.1 → NP_001291991.1  testis-expressed protein 35 isoform 3

      See identical proteins and their annotated locations for NP_001291991.1

      Status: VALIDATED

      Source sequence(s)
      AC119220, AK006825, BY080014, CJ232085
      Consensus CDS
      CCDS78716.1
      UniProtKB/Swiss-Prot
      Q14BK3, Q4KKY9, Q9D9J9
      UniProtKB/TrEMBL
      D3Z4U7
      Related
      ENSMUSP00000113622.2, ENSMUST00000121911.8
      Conserved Domains (1) summary
      pfam15079
      Location:1 → 172
      Tsc35; Testis-specific protein 35

    4. NM_001305063.1 → NP_001291992.1  testis-expressed protein 35 isoform 4

      Status: VALIDATED

      Source sequence(s)
      AC119220, AK006825, BY080014, CJ232085
      Consensus CDS
      CCDS78715.1
      UniProtKB/Swiss-Prot
      Q14BK3, Q4KKY9, Q9D9J9
      UniProtKB/TrEMBL
      D3Z652
      Related
      ENSMUSP00000113325.2, ENSMUST00000119526.2
      Conserved Domains (1) summary
      pfam15079
      Location:1 → 173
      Tsc35; Testis-specific protein 35

    5. NM_001374637.1 → NP_001361566.1  testis-expressed protein 35 isoform 5

      Status: VALIDATED

      Source sequence(s)
      AC119220
      Consensus CDS
      CCDS87897.1
      UniProtKB/Swiss-Prot
      Q14BK3, Q4KKY9, Q9D9J9
      UniProtKB/TrEMBL
      A0A087WNR4
      Related
      ENSMUSP00000139460.2, ENSMUST00000187546.7
      Conserved Domains (1) summary
      pfam15079
      Location:1 → 179
      Tsc35; Testis-specific protein 35

    6. NM_001400230.1 → NP_001387159.1  testis-expressed protein 35 isoform 6

      Status: VALIDATED

      Source sequence(s)
      AC119220

    7. NM_001400232.1 → NP_001387161.1  testis-expressed protein 35 isoform 7

      Status: VALIDATED

      Source sequence(s)
      AC119220

    8. NM_001400233.1 → NP_001387162.1  testis-expressed protein 35 isoform 4

      Status: VALIDATED

      Source sequence(s)
      AC119220
      UniProtKB/TrEMBL
      D3Z652

    9. NM_028540.3 → NP_082816.1  testis-expressed protein 35 isoform 1

      See identical proteins and their annotated locations for NP_082816.1

      Status: VALIDATED

      Source sequence(s)
      AC119220, AK006825, BY706810, CJ232085
      Consensus CDS
      CCDS48407.1
      UniProtKB/Swiss-Prot
      Q14BK3, Q4KKY9, Q9D9J9
      UniProtKB/TrEMBL
      A0A0R4J1P6
      Related
      ENSMUSP00000114092.2, ENSMUST00000118207.8
      Conserved Domains (1) summary
      pfam15079
      Location:1 → 193
      Tsc35; Testis-specific protein 35

    RefSeqs of Annotated Genomes: GCF_000001635.27-RS_2024_02

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCm39 C57BL/6J

    Genomic

    1. NC_000067.7 Reference GRCm39 C57BL/6J

      Range
      156926711..156938506 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_036153771.1 → XP_036009664.1  testis-expressed protein 35 isoform X2

      Conserved Domains (1) summary
      pfam15079
      Location:1 → 154
      Tsc35; Testis-specific protein 35

    2. XM_017312462.3 → XP_017167951.1  testis-expressed protein 35 isoform X2

      Conserved Domains (1) summary
      pfam15079
      Location:1 → 154
      Tsc35; Testis-specific protein 35

    3. XM_017312459.1 → XP_017167948.1  testis-expressed protein 35 isoform X2

      Conserved Domains (1) summary
      pfam15079
      Location:1 → 154
      Tsc35; Testis-specific protein 35

    4. XM_017312460.1 → XP_017167949.1  testis-expressed protein 35 isoform X2

      Conserved Domains (1) summary
      pfam15079
      Location:1 → 154
      Tsc35; Testis-specific protein 35
    Nucleotide Protein Strain
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    Q14BK3.1 GenPept UniProtKB/Swiss-Prot:Q14BK3

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