Shcbp1l Shc SH2-domain binding protein 1-like [Mus musculus (house mouse)] - Gene

Summary

Official Symbol: Shcbp1lprovided by MGI
Official Full Name: Shc SH2-domain binding protein 1-likeprovided by MGI
Primary source: MGI:MGI:1919086
See related: Ensembl:ENSMUSG00000042708 AllianceGenome:MGI:1919086
Gene type: protein coding
RefSeq status: PROVISIONAL
Organism: Mus musculus
Lineage: Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
Also known as: 1700012A16Rik
Summary: Involved in positive regulation of chromosome organization and spermatogenesis. Located in meiotic spindle. Orthologous to human SHCBP1L (SHC binding and spindle associated 1 like). [provided by Alliance of Genome Resources, Apr 2022]
Expression: Biased expression in testis adult (RPKM 27.7) and cerebellum adult (RPKM 0.6) See more
Orthologs: human all
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Genomic context

Location:: 1 G3; 1 65.36 cM

Exon count:: 11

Annotation release	Status	Assembly	Chr	Location
RS_2024_02	current	GRCm39 (GCF_000001635.27)	1	NC_000067.7 (153300846..153328320)
108.20200622	previous assembly	GRCm38.p6 (GCF_000001635.26)	1	NC_000067.6 (153425100..153452584)

Chromosome 1 - NC_000067.7 Genomic Context describing neighboring genes

Genomic regions, transcripts, and products

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Genomic Sequence:

Go to nucleotide: Graphics FASTA GenBank

Expression

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See details

Project title: Mouse ENCODE transcriptome data
Description: RNA profiling data sets generated by the Mouse ENCODE project.
BioProject: PRJNA66167
Publication: PMID 25409824
Analysis date: n/a

Bibliography

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GeneRIFs: Gene References Into Functions

What's a GeneRIF?

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Variation

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Alleles

Alleles of this type are documented at Mouse Genome Informatics (MGI)

Endonuclease-mediated (2)
Targeted (1)

General gene information

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Gene Ontology Provided by MGI

Function	Evidence Code	Pubs
enables protein binding	IPI Inferred from Physical Interaction more info	PubMed

Process	Evidence Code	Pubs
acts_upstream_of_or_within cell differentiation	IEA Inferred from Electronic Annotation more info
involved_in male meiosis cytokinesis	IBA Inferred from Biological aspect of Ancestor more info
involved_in positive regulation of chromosome organization	IMP Inferred from Mutant Phenotype more info	PubMed
involved_in spermatogenesis	IBA Inferred from Biological aspect of Ancestor more info
involved_in spermatogenesis	IMP Inferred from Mutant Phenotype more info	PubMed

Component	Evidence Code	Pubs
located_in cytoplasm	IEA Inferred from Electronic Annotation more info
located_in cytoskeleton	IEA Inferred from Electronic Annotation more info
is_active_in meiotic spindle	IBA Inferred from Biological aspect of Ancestor more info
located_in meiotic spindle	IDA Inferred from Direct Assay more info	PubMed

General protein information

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Preferred Names: testicular spindle-associated protein SHCBP1L

Names: SHC SH2 domain-binding protein 1-like protein

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.