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    fbxo11a F-box protein 11a [ Danio rerio (zebrafish) ]

    Gene ID: 777607, updated on 27-Mar-2024

    Summary

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    Official Symbol
    fbxo11aprovided by ZNC
    Official Full Name
    F-box protein 11aprovided by ZNC
    Primary source
    ZFIN:ZDB-GENE-061103-70
    See related
    Ensembl:ENSDARG00000102294 AllianceGenome:ZFIN:ZDB-GENE-061103-70
    Gene type
    protein coding
    RefSeq status
    PROVISIONAL
    Organism
    Danio rerio
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Actinopterygii; Neopterygii; Teleostei; Ostariophysi; Cypriniformes; Danionidae; Danioninae; Danio
    Also known as
    fbxo11; fj83f06; im:6906507; wu:fj83f06; zgc:153171
    Summary
    Predicted to enable zinc ion binding activity. Predicted to be involved in protein ubiquitination; regulation of apoptotic process; and ubiquitin-dependent protein catabolic process. Predicted to be part of ubiquitin ligase complex. Orthologous to human FBXO11 (F-box protein 11). [provided by Alliance of Genome Resources, Apr 2022]
    Orthologs
    all
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    Genomic context

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    See fbxo11a in Genome Data Viewer
    Location:
    chromosome: 13
    Exon count:
    22
    Annotation release Status Assembly Chr Location
    106 current GRCz11 (GCF_000002035.6) 13 NC_007124.7 (48381035..48431793, complement)
    105 previous assembly GRCz10 (GCF_000002035.5) 13 NC_007124.6 (48090455..48140763, complement)

    Chromosome 13 - NC_007124.7Genomic Context describing neighboring genes Neighboring gene golgin A4 Neighboring gene potassium channel, subfamily K, member 12 Neighboring gene mutS homolog 6 (E. coli) Neighboring gene forkhead box N2a Neighboring gene uncharacterized LOC100149084

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Expression

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    • Project title: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
    • Description: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
    • BioProject: PRJEB1986
    • Analysis date: Fri Dec 8 19:48:10 2017

    Bibliography

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    Related articles in PubMed

    1. A network of epigenetic regulators guides developmental haematopoiesis in vivo. Huang HT, et al. Nat Cell Biol, 2013 Dec. PMID 24240475, Free PMC Article
    2. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. Strausberg RL, et al. Proc Natl Acad Sci U S A, 2002 Dec 24. PMID 12477932, Free PMC Article
    3. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, et al. Brief Bioinform, 2011 Sep. PMID 21873635, Free PMC Article
    4. Gene evolution and gene expression after whole genome duplication in fish: the PhyloFish database. Pasquier J, et al. BMC Genomics, 2016 May 18. PMID 27189481, Free PMC Article

    GeneRIFs: Gene References Into Functions

    General gene information

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    Markers

    Homology

    Clone Names

    • FLJ12673

    Gene Ontology Provided by ZFIN

    Function Evidence Code Pubs
    enables metal ion binding IEA
    Inferred from Electronic Annotation
    more info
    		  
    enables zinc ion binding IEA
    Inferred from Electronic Annotation
    more info
    		  
    Process Evidence Code Pubs
    involved_in regulation of apoptotic process IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    involved_in ubiquitin-dependent protein catabolic process IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  

    General protein information

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    Preferred Names
    F-box only protein 11a; F-box protein 11a
    Names
    F-box protein 11

    NCBI Reference Sequences (RefSeq)

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    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001159668.1 → NP_001153140.1  F-box only protein 11a

      Status: PROVISIONAL

      Source sequence(s)
      CU463106, CU468002
      UniProtKB/TrEMBL
      A0A0R4IJR2, A0A8M1NRC2
      Related
      ENSDARP00000134626.1, ENSDART00000159688.2
      Conserved Domains (4) summary
      TIGR03804
      Location:479 → 521
      para_beta_helix; parallel beta-helix repeat (two copies)
      pfam12937
      Location:111 → 154
      F-box-like; F-box-like
      pfam13229
      Location:616 → 761
      Beta_helix; Right handed beta helix region
      cl19744
      Location:802 → 832
      zf-UBR; Putative zinc finger in N-recognin (UBR box)

    RefSeqs of Annotated Genomes: Danio rerio Annotation Release 106 details...Open this link in a new tab

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCz11 Primary Assembly

    Genomic

    1. NC_007124.7 Reference GRCz11 Primary Assembly

      Range
      48381035..48431793 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_005169554.4 → XP_005169611.1  F-box protein 11a isoform X1

      UniProtKB/TrEMBL
      A0A0R4IXA1, A0A8M2BGY5
      Related
      ENSDARP00000140781.1, ENSDART00000171765.2
      Conserved Domains (4) summary
      TIGR03804
      Location:479 → 521
      para_beta_helix; parallel beta-helix repeat (two copies)
      pfam02207
      Location:802 → 843
      zf-UBR; Putative zinc finger in N-recognin (UBR box)
      pfam12937
      Location:111 → 154
      F-box-like; F-box-like
      pfam13229
      Location:616 → 775
      Beta_helix; Right handed beta helix region

    RNA

    1. XR_002459814.1 RNA Sequence

    Nucleotide Protein
    Heading Accession and Version

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