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    gnptg N-acetylglucosamine-1-phosphate transferase subunit gamma [ Danio rerio (zebrafish) ]

    Gene ID: 415147, updated on 27-Mar-2024

    Summary

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    Official Symbol
    gnptgprovided by ZNC
    Official Full Name
    N-acetylglucosamine-1-phosphate transferase subunit gammaprovided by ZNC
    Primary source
    ZFIN:ZDB-GENE-040625-18
    See related
    Ensembl:ENSDARG00000038566 AllianceGenome:ZFIN:ZDB-GENE-040625-18
    Gene type
    protein coding
    RefSeq status
    VALIDATED
    Organism
    Danio rerio
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Actinopterygii; Neopterygii; Teleostei; Ostariophysi; Cypriniformes; Danionidae; Danioninae; Danio
    Also known as
    zgc:86640; wu:fc79g04
    Summary
    Predicted to enable transferase activity. Predicted to be active in Golgi apparatus. Human ortholog(s) of this gene implicated in glycoproteinosis and mucolipidosis III gamma. Orthologous to human GNPTG (N-acetylglucosamine-1-phosphate transferase subunit gamma). [provided by Alliance of Genome Resources, Apr 2022]
    Orthologs
    human mouse all
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    Genomic context

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    See gnptg in Genome Data Viewer
    Location:
    chromosome: 24
    Exon count:
    10
    Annotation release Status Assembly Chr Location
    106 current GRCz11 (GCF_000002035.6) 24 NC_007135.7 (37338430..37347858)
    105 previous assembly GRCz10 (GCF_000002035.5) 24 NC_007135.6 (37450710..37460138)

    Chromosome 24 - NC_007135.7Genomic Context describing neighboring genes Neighboring gene 3-phosphoinositide dependent protein kinase 1b Neighboring gene TSR3 ribosome maturation factor Neighboring gene SH3 domain binding kinase 1 Neighboring gene si:ch211-183d21.1

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Expression

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    • Project title: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
    • Description: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
    • BioProject: PRJEB1986
    • Analysis date: Fri Dec 8 19:48:10 2017

    Bibliography

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    Related articles in PubMed

    1. Enzyme-specific differences in mannose phosphorylation between GlcNAc-1-phosphotransferase αβ and γ subunit deficient zebrafish support cathepsin proteases as early mediators of mucolipidosis pathology. Flanagan-Steet H, et al. Biochim Biophys Acta, 2016 Sep. PMID 27241848, Free PMC Article
    2. A genomic view of the NOD-like receptor family in teleost fish: identification of a novel NLR subfamily in zebrafish. Laing KJ, et al. BMC Evol Biol, 2008 Feb 6. PMID 18254971, Free PMC Article
    3. The zebrafish gene map defines ancestral vertebrate chromosomes. Woods IG, et al. Genome Res, 2005 Sep. PMID 16109975, Free PMC Article
    4. RFX transcription factors are essential for hearing in mice. Elkon R, et al. Nat Commun, 2015 Oct 15. PMID 26469318, Free PMC Article
    5. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. Strausberg RL, et al. Proc Natl Acad Sci U S A, 2002 Dec 24. PMID 12477932, Free PMC Article

    See all (6) citations in PubMed

    GeneRIFs: Gene References Into Functions

    General gene information

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    Markers

    Homology

    Gene Ontology Provided by ZFIN

    Component Evidence Code Pubs
    is_active_in Golgi apparatus IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  

    General protein information

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    Preferred Names
    N-acetylglucosamine-1-phosphotransferase subunit gamma
    Names
    N-acetylglucosamine-1-phosphate transferase, gamma subunit

    NCBI Reference Sequences (RefSeq)

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    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001002057.2 → NP_001002057.2  N-acetylglucosamine-1-phosphotransferase subunit gamma precursor

      Status: VALIDATED

      Source sequence(s)
      CU469584, EH432365, EH511194
      UniProtKB/TrEMBL
      A0A8M1MZR8
      Related
      ENSDARP00000121022.1, ENSDART00000141771.2
      Conserved Domains (1) summary
      pfam07915
      Location:67 → 127
      PRKCSH; Glucosidase II beta subunit-like protein

    RefSeqs of Annotated Genomes: Danio rerio Annotation Release 106 details...Open this link in a new tab

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCz11 Primary Assembly

    Genomic

    1. NC_007135.7 Reference GRCz11 Primary Assembly

      Range
      37338430..37347858
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)
    Nucleotide Protein Strain
    Heading Accession and Version

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