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    Fam227a family with sequence similarity 227, member A [ Mus musculus (house mouse) ]

    Gene ID: 75729, updated on 5-Mar-2024

    Summary

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    Official Symbol
    Fam227aprovided by MGI
    Official Full Name
    family with sequence similarity 227, member Aprovided by MGI
    Primary source
    MGI:MGI:1922979
    See related
    Ensembl:ENSMUSG00000042564 AllianceGenome:MGI:1922979
    Gene type
    protein coding
    RefSeq status
    VALIDATED
    Organism
    Mus musculus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
    Also known as
    4933432B09Rik
    Summary
    Orthologous to human FAM227A (family with sequence similarity 227 member A). [provided by Alliance of Genome Resources, Apr 2022]
    Expression
    Biased expression in whole brain E14.5 (RPKM 3.4), testis adult (RPKM 3.1) and 13 other tissues See more
    Orthologs
    human all
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    Genomic context

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    Location:
    15 E1; 15 37.81 cM
    Exon count:
    19
    Annotation release Status Assembly Chr Location
    RS_2024_02 current GRCm39 (GCF_000001635.27) 15 NC_000081.7 (79493777..79543157, complement)
    108.20200622 previous assembly GRCm38.p6 (GCF_000001635.26) 15 NC_000081.6 (79609576..79658956, complement)

    Chromosome 15 - NC_000081.7Genomic Context describing neighboring genes Neighboring gene KDEL (Lys-Asp-Glu-Leu) endoplasmic reticulum protein retention receptor 3 Neighboring gene DEAD box helicase 17 Neighboring gene STARR-seq mESC enhancer starr_39189 Neighboring gene DNA meiotic recombinase 1 Neighboring gene STARR-seq mESC enhancer starr_39191 Neighboring gene STARR-seq mESC enhancer starr_39193 Neighboring gene predicted gene, 30877 Neighboring gene chibby family member 1, beta catenin antagonist Neighboring gene translocase of outer mitochondrial membrane 22

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Expression

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    • Project title: Mouse ENCODE transcriptome data
    • Description: RNA profiling data sets generated by the Mouse ENCODE project.
    • BioProject: PRJNA66167
    • Publication: PMID 25409824
    • Analysis date: n/a

    Bibliography

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    Related articles in PubMed

    1. Large-scale gene trapping in C57BL/6N mouse embryonic stem cells. Hansen GM, et al. Genome Res, 2008 Oct. PMID 18799693, Free PMC Article
    2. A conditional knockout resource for the genome-wide study of mouse gene function. Skarnes WC, et al. Nature, 2011 Jun 15. PMID 21677750, Free PMC Article
    3. Wnk1 kinase deficiency lowers blood pressure in mice: a gene-trap screen to identify potential targets for therapeutic intervention. Zambrowicz BP, et al. Proc Natl Acad Sci U S A, 2003 Nov 25. PMID 14610273, Free PMC Article
    4. Antisense transcription in the mammalian transcriptome. Katayama S, et al. Science, 2005 Sep 2. PMID 16141073
    5. High-efficiency full-length cDNA cloning. Carninci P, et al. Methods Enzymol, 1999. PMID 10349636

    See all (11) citations in PubMed

    GeneRIFs: Gene References Into Functions

    Variation

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    Alleles

    Alleles of this type are documented at Mouse Genome Informatics  (MGI)
    • Endonuclease-mediated (1) 

    General gene information

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    Homology

    Gene Ontology Provided by MGI

    Function Evidence Code Pubs
    enables molecular_function ND
    No biological Data available
    more info
    		  
    Process Evidence Code Pubs
    involved_in biological_process ND
    No biological Data available
    more info
    		  
    Component Evidence Code Pubs
    is_active_in cellular_component ND
    No biological Data available
    more info
    		  

    General protein information

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    Preferred Names
    protein FAM227A

    NCBI Reference Sequences (RefSeq)

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    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_029407.1 → NP_083683.1  protein FAM227A

      See identical proteins and their annotated locations for NP_083683.1

      Status: VALIDATED

      Source sequence(s)
      AC117806, AK017017, AK039547
      Consensus CDS
      CCDS79389.1
      UniProtKB/TrEMBL
      Q9D3V8
      Related
      ENSMUSP00000139524.2, ENSMUST00000187519.7
      Conserved Domains (1) summary
      pfam14922
      Location:145 → 295
      FWWh; Protein of unknown function

    RefSeqs of Annotated Genomes: GCF_000001635.27-RS_2024_02

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCm39 C57BL/6J

    Genomic

    1. NC_000081.7 Reference GRCm39 C57BL/6J

      Range
      79493777..79543157 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_030248810.1 → XP_030104670.1  protein FAM227A isoform X6

      Conserved Domains (1) summary
      pfam14922
      Location:15 → 138
      FWWh; Protein of unknown function

    2. XM_030248811.1 → XP_030104671.1  protein FAM227A isoform X7

      Conserved Domains (1) summary
      pfam14922
      Location:1 → 104
      FWWh; Protein of unknown function

    3. XM_030248809.1 → XP_030104669.1  protein FAM227A isoform X2

      UniProtKB/TrEMBL
      A0A2R8VHN9
      Related
      ENSMUSP00000155261.2, ENSMUST00000229064.2
      Conserved Domains (1) summary
      pfam14922
      Location:141 → 291
      FWWh; Protein of unknown function

    4. XM_030248813.2 → XP_030104673.1  protein FAM227A isoform X10

    5. XM_006521510.4 → XP_006521573.1  protein FAM227A isoform X5

      See identical proteins and their annotated locations for XP_006521573.1

      Conserved Domains (1) summary
      pfam14922
      Location:76 → 226
      FWWh; Protein of unknown function

    6. XM_017316779.2 → XP_017172268.1  protein FAM227A isoform X4

      Conserved Domains (1) summary
      pfam14922
      Location:141 → 239
      FWWh; Protein of unknown function

    7. XM_017316777.2 → XP_017172266.1  protein FAM227A isoform X2

      UniProtKB/TrEMBL
      A0A2R8VHN9
      Conserved Domains (1) summary
      pfam14922
      Location:141 → 291
      FWWh; Protein of unknown function

    8. XM_017316778.2 → XP_017172267.1  protein FAM227A isoform X3

      Conserved Domains (1) summary
      pfam14922
      Location:145 → 243
      FWWh; Protein of unknown function

    9. XM_011245765.3 → XP_011244067.1  protein FAM227A isoform X1

      See identical proteins and their annotated locations for XP_011244067.1

      UniProtKB/TrEMBL
      Q9D3V8
      Conserved Domains (1) summary
      pfam14922
      Location:145 → 295
      FWWh; Protein of unknown function

    10. XM_011245760.3 → XP_011244062.1  protein FAM227A isoform X5

      See identical proteins and their annotated locations for XP_011244062.1

      Conserved Domains (1) summary
      pfam14922
      Location:76 → 226
      FWWh; Protein of unknown function

    11. XM_017316781.3 → XP_017172270.1  protein FAM227A isoform X6

      Conserved Domains (1) summary
      pfam14922
      Location:15 → 138
      FWWh; Protein of unknown function

    12. XM_011245764.2 → XP_011244066.1  protein FAM227A isoform X12

      UniProtKB/TrEMBL
      Q08EB1

    13. XM_017316784.2 → XP_017172273.1  protein FAM227A isoform X9

      Conserved Domains (1) summary
      pfam14922
      Location:145 → 295
      FWWh; Protein of unknown function

    14. XM_017316783.2 → XP_017172272.1  protein FAM227A isoform X8

      Conserved Domains (1) summary
      pfam14922
      Location:145 → 295
      FWWh; Protein of unknown function

    15. XM_017316785.2 → XP_017172274.1  protein FAM227A isoform X11

      Conserved Domains (1) summary
      pfam14922
      Location:145 → 295
      FWWh; Protein of unknown function

    16. XM_036159622.1 → XP_036015515.1  protein FAM227A isoform X11

      Conserved Domains (1) summary
      pfam14922
      Location:145 → 295
      FWWh; Protein of unknown function

    RNA

    1. XR_004938876.1 RNA Sequence

    2. XR_003951444.1 RNA Sequence

    3. XR_001781574.2 RNA Sequence

    Nucleotide Protein Strain
    Heading Accession and Version

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