NCBI Home Page NCBI Site Search page NCBI Guide that lists and describes the NCBI resources
Conserved domains on  [gi|1039749654|ref|XP_017172268|]
View 

protein FAM227A isoform X4 [Mus musculus]

Protein Classification

Graphical summary

 Zoom to residue level

show extra options »

Show site features     Horizontal zoom: ×

List of domain hits

 Name Accession Description Interval E-value
FWWh super family cl20808
Protein of unknown function; This is a family of eukaryotic proteins. Most members carry a ...
 141-239 8.07e-44

Protein of unknown function; This is a family of eukaryotic proteins. Most members carry a highly distinctive, conserved sequence motif of FWWh, where h represents a hydrophobic residue. The function of the family is not known.


The actual alignment was detected with superfamily member pfam14922:

Pssm-ID: 464378  Cd Length: 150  Bit Score: 152.79  E-value: 8.07e-44
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039749654 141 PNKLPNGVDFCDMVGNVIRSEKNPLsgKSYCSDRELEKFLCSPFLAAMWLDSFWWLFHERYQPDKEIQKKLFDRIARNYA 220
Cdd:pfam14922   1 LTPLPNQVEAKQMLGNVLRAQKFLL--KKPCYKKEWKKFFLSEASQAILLDSFWWFFLERYQPDKESQDKLFDRIAENYV 78

                          90
                  ....*....|....*....
gi 1039749654 221 SLLFKMCRSHYEEALLKSY 239
Cdd:pfam14922  79 KLLLTAPRPDYKDAFFKRY 97
 
Name Accession Description Interval E-value
FWWh pfam14922
Protein of unknown function; This is a family of eukaryotic proteins. Most members carry a ...
 141-239 8.07e-44

Protein of unknown function; This is a family of eukaryotic proteins. Most members carry a highly distinctive, conserved sequence motif of FWWh, where h represents a hydrophobic residue. The function of the family is not known.


Pssm-ID: 464378  Cd Length: 150  Bit Score: 152.79  E-value: 8.07e-44
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039749654 141 PNKLPNGVDFCDMVGNVIRSEKNPLsgKSYCSDRELEKFLCSPFLAAMWLDSFWWLFHERYQPDKEIQKKLFDRIARNYA 220
Cdd:pfam14922   1 LTPLPNQVEAKQMLGNVLRAQKFLL--KKPCYKKEWKKFFLSEASQAILLDSFWWFFLERYQPDKESQDKLFDRIAENYV 78

                          90
                  ....*....|....*....
gi 1039749654 221 SLLFKMCRSHYEEALLKSY 239
Cdd:pfam14922  79 KLLLTAPRPDYKDAFFKRY 97
 
Name Accession Description Interval E-value
FWWh pfam14922
Protein of unknown function; This is a family of eukaryotic proteins. Most members carry a ...
 141-239 8.07e-44

Protein of unknown function; This is a family of eukaryotic proteins. Most members carry a highly distinctive, conserved sequence motif of FWWh, where h represents a hydrophobic residue. The function of the family is not known.


Pssm-ID: 464378  Cd Length: 150  Bit Score: 152.79  E-value: 8.07e-44
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039749654 141 PNKLPNGVDFCDMVGNVIRSEKNPLsgKSYCSDRELEKFLCSPFLAAMWLDSFWWLFHERYQPDKEIQKKLFDRIARNYA 220
Cdd:pfam14922   1 LTPLPNQVEAKQMLGNVLRAQKFLL--KKPCYKKEWKKFFLSEASQAILLDSFWWFFLERYQPDKESQDKLFDRIAENYV 78

                          90
                  ....*....|....*....
gi 1039749654 221 SLLFKMCRSHYEEALLKSY 239
Cdd:pfam14922  79 KLLLTAPRPDYKDAFFKRY 97
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
Help | Disclaimer | Write to the Help Desk
NCBI | NLM | NIH