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    Tmem184c transmembrane protein 184C [ Mus musculus (house mouse) ]

    Gene ID: 234463, updated on 11-Apr-2024

    Summary

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    Official Symbol
    Tmem184cprovided by MGI
    Official Full Name
    transmembrane protein 184Cprovided by MGI
    Primary source
    MGI:MGI:2384562
    See related
    Ensembl:ENSMUSG00000031617 AllianceGenome:MGI:2384562
    Gene type
    protein coding
    RefSeq status
    VALIDATED
    Organism
    Mus musculus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
    Also known as
    Tmem34; 8430433H16Rik
    Summary
    Predicted to be located in membrane. Predicted to be integral component of membrane. Is expressed in incisor; nervous system; and olfactory epithelium. Orthologous to human TMEM184C (transmembrane protein 184C). [provided by Alliance of Genome Resources, Apr 2022]
    Expression
    Broad expression in cerebellum adult (RPKM 19.9), CNS E14 (RPKM 16.3) and 23 other tissues See more
    Orthologs
    human all
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    Genomic context

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    Location:
    8 C1; 8 36.61 cM
    Exon count:
    11
    Annotation release Status Assembly Chr Location
    RS_2024_02 current GRCm39 (GCF_000001635.27) 8 NC_000074.7 (78322607..78337343, complement)
    108.20200622 previous assembly GRCm38.p6 (GCF_000001635.26) 8 NC_000074.6 (77595978..77610714, complement)

    Chromosome 8 - NC_000074.7Genomic Context describing neighboring genes Neighboring gene Rho GTPase activating protein 10 Neighboring gene RIKEN cDNA 0610038B21 gene Neighboring gene STARR-seq mESC enhancer starr_21957 Neighboring gene STARR-positive B cell enhancer ABC_E9317 Neighboring gene STARR-positive B cell enhancer ABC_E8249 Neighboring gene STARR-seq mESC enhancer starr_21958 Neighboring gene protein arginine methyltransferase 9 Neighboring gene STARR-positive B cell enhancer ABC_E1761 Neighboring gene RIKEN cDNA 4933431K23 gene Neighboring gene RIKEN cDNA 1700092C02 gene Neighboring gene predicted gene, 39200

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Expression

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    • Project title: Mouse ENCODE transcriptome data
    • Description: RNA profiling data sets generated by the Mouse ENCODE project.
    • BioProject: PRJNA66167
    • Publication: PMID 25409824
    • Analysis date: n/a

    Bibliography

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    Related articles in PubMed

    1. A neurogenomics approach to gene expression analysis in the developing brain. Jensen P, et al. Brain Res Mol Brain Res, 2004 Dec 20. PMID 15582152
    2. The level of the transcription factor Pax6 is essential for controlling the balance between neural stem cell self-renewal and neurogenesis. Sansom SN, et al. PLoS Genet, 2009 Jun. PMID 19521500, Free PMC Article
    3. Isolation of novel tissue-specific genes from cDNA libraries representing the individual tissue constituents of the gastrulating mouse embryo. Harrison SM, et al. Development, 1995 Aug. PMID 7671812
    4. BGEM: an in situ hybridization database of gene expression in the embryonic and adult mouse nervous system. Magdaleno S, et al. PLoS Biol, 2006 Apr. PMID 16602821, Free PMC Article
    5. Libraries enriched for alternatively spliced exons reveal splicing patterns in melanocytes and melanomas. Watahiki A, et al. Nat Methods, 2004 Dec. PMID 15782199

    See all (16) citations in PubMed

    GeneRIFs: Gene References Into Functions

    Variation

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    Alleles

    Alleles of this type are documented at Mouse Genome Informatics  (MGI)
    • Endonuclease-mediated (2) 

    General gene information

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    Markers

    Homology

    Clone Names

    • MGC8158

    Gene Ontology Provided by MGI

    Function Evidence Code Pubs
    enables transporter activity IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    Process Evidence Code Pubs
    involved_in transport IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    Component Evidence Code Pubs
    is_active_in membrane IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  

    General protein information

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    Preferred Names
    transmembrane protein 184C
    Names
    transmembrane protein 34

    NCBI Reference Sequences (RefSeq)

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    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001364445.1 → NP_001351374.1  transmembrane protein 184C isoform 2

      Status: VALIDATED

      Source sequence(s)
      AC113049, AK033404, CO433630
      Conserved Domains (1) summary
      pfam03619
      Location:90 → 356
      Solute_trans_a; Organic solute transporter Ostalpha

    2. NM_145599.4 → NP_663574.3  transmembrane protein 184C isoform 1

      Status: VALIDATED

      Source sequence(s)
      AK033404, CN532034, CO433630
      Consensus CDS
      CCDS22426.1
      UniProtKB/Swiss-Prot
      Q3TPR7, Q8CCD2, Q99KQ7
      Related
      ENSMUSP00000034030.9, ENSMUST00000034030.15
      Conserved Domains (1) summary
      pfam03619
      Location:49 → 316
      Solute_trans_a; Organic solute transporter Ostalpha

    RefSeqs of Annotated Genomes: GCF_000001635.27-RS_2024_02

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCm39 C57BL/6J

    Genomic

    1. NC_000074.7 Reference GRCm39 C57BL/6J

      Range
      78322607..78337343 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)
    Nucleotide Protein Strain
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    Q3TPR7.1 GenPept UniProtKB/Swiss-Prot:Q3TPR7

    Gene LinkOut

    The following LinkOut resources are supplied by external providers. These providers are responsible for maintaining the links.

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