Zfp93 zinc finger protein 93 [Mus musculus (house mouse)] - Gene

Summary

Official Symbol: Zfp93provided by MGI
Official Full Name: zinc finger protein 93provided by MGI
Primary source: MGI:MGI:107611
See related: Ensembl:ENSMUSG00000055305 AllianceGenome:MGI:107611
Gene type: protein coding
RefSeq status: VALIDATED
Organism: Mus musculus
Lineage: Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
Also known as: Znf235
Summary: Predicted to enable DNA-binding transcription factor activity, RNA polymerase II-specific and RNA polymerase II cis-regulatory region sequence-specific DNA binding activity. Predicted to be involved in regulation of transcription by RNA polymerase II. Predicted to be active in nucleus. Is expressed in bladder; female associated reproductive structure; and ureter. Orthologous to human ZNF235 (zinc finger protein 235). [provided by Alliance of Genome Resources, Apr 2022]
Expression: Ubiquitous expression in CNS E18 (RPKM 1.4), CNS E14 (RPKM 1.3) and 28 other tissues See more
NEW: Try the new Gene table
Try the new Transcript table

Genomic context

Location:: 7 A3; 7 10.27 cM

Exon count:: 6

Annotation release	Status	Assembly	Chr	Location
RS_2024_02	current	GRCm39 (GCF_000001635.27)	7	NC_000073.7 (23967406..23977219)
108.20200622	previous assembly	GRCm38.p6 (GCF_000001635.26)	7	NC_000073.6 (24267984..24277794)

Chromosome 7 - NC_000073.7 Genomic Context describing neighboring genes

Genomic regions, transcripts, and products

Go to the top of the page Help

Go to reference sequence details

Genomic Sequence:

Go to nucleotide: Graphics FASTA GenBank

Expression

Go to the top of the page Help

See details

Project title: Mouse ENCODE transcriptome data
Description: RNA profiling data sets generated by the Mouse ENCODE project.
BioProject: PRJNA66167
Publication: PMID 25409824
Analysis date: n/a

Bibliography

Go to the top of the page Help

GeneRIFs: Gene References Into Functions

What's a GeneRIF?

Zfp93 zinc finger protein 93
Title: Comparative analysis of a conserved zinc finger gene cluster on human chromosome 19q and mouse chromosome 7.

Submit: New GeneRIF Correction

Variation

Go to the top of the page Help

Alleles

Alleles of this type are documented at Mouse Genome Informatics (MGI)

Gene trapped (1)

Interactions

Go to the top of the page Help

Products	Interactant	Other Gene	Complex	Source	Pubs	Description

General gene information

Go to the top of the page Help

Gene Ontology Provided by MGI

Function	Evidence Code	Pubs
enables DNA binding	IEA Inferred from Electronic Annotation more info
enables metal ion binding	IEA Inferred from Electronic Annotation more info

Process	Evidence Code	Pubs
involved_in regulation of DNA-templated transcription	IEA Inferred from Electronic Annotation more info

Component	Evidence Code	Pubs
located_in nucleus	IEA Inferred from Electronic Annotation more info

General protein information

Go to the top of the page Help

Preferred Names: zinc finger protein 235

Names: zfp-93

NCBI Reference Sequences (RefSeq)

Go to the top of the page Help

NEW Try the new Transcript table

RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

NM_001360227.1 → NP_001347156.1 zinc finger protein 235 isoform 1

Status: VALIDATED

Description

Transcript Variant: This variant (1) represents the longest transcript and encodes the longer isoform (1).

Source sequence(s)

AC159140

Conserved Domains (3) summary

COG5048
Location:275 → 613

COG5048; FOG: Zn-finger [General function prediction only]

sd00017
Location:333 → 353

ZF_C2H2; C2H2 Zn finger [structural motif]

pfam01352
Location:25 → 66

KRAB; KRAB box
NM_009567.4 → NP_033593.1 zinc finger protein 235 isoform 2

See identical proteins and their annotated locations for NP_033593.1

Status: VALIDATED

Description

Transcript Variant: This variant (2) differs in the 5' UTR and coding sequence compared to variant 1. The resulting isoform (2) is shorter at the N-terminus compared to isoform 1.

Source sequence(s)

AK132229

Consensus CDS

CCDS39828.1

UniProtKB/Swiss-Prot

Q3UKA3, Q61116, Q8CE70

Related

ENSMUSP00000104077.4, ENSMUST00000108438.10

Conserved Domains (4) summary

COG5048
Location:257 → 595

COG5048; FOG: Zn-finger [General function prediction only]

sd00017
Location:315 → 335

ZF_C2H2; C2H2 Zn finger [structural motif]

pfam01352
Location:7 → 48

KRAB; KRAB box

pfam13465
Location:608 → 632

zf-H2C2_2; Zinc-finger double domain

RNA

NR_153420.1 RNA Sequence

Status: VALIDATED

Description

Transcript Variant: This variant (3) differs in the 3' end compared to variant 1. This variant is represented as non-coding because the predicted protein does not meet RefSeq quality criteria.

Source sequence(s)

AC159140, BM935074

RefSeqs of Annotated Genomes: GCF_000001635.27-RS_2024_02

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCm39 C57BL/6J

Genomic

NC_000073.7 Reference GRCm39 C57BL/6J

Range

23967406..23977219

Download

GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

XM_017322143.2 → XP_017177632.1 zinc finger protein 235 isoform X1

UniProtKB/Swiss-Prot

Q3UKA3, Q61116, Q8CE70

Conserved Domains (4) summary

COG5048
Location:257 → 595

COG5048; FOG: Zn-finger [General function prediction only]

sd00017
Location:315 → 335

ZF_C2H2; C2H2 Zn finger [structural motif]

pfam01352
Location:7 → 48

KRAB; KRAB box

pfam13465
Location:608 → 632

zf-H2C2_2; Zinc-finger double domain