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    Zfa-ps zinc finger protein, autosomal, pseudogene [ Mus musculus (house mouse) ]

    Gene ID: 22639, updated on 11-Apr-2024

    Summary

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    Official Symbol
    Zfa-psprovided by MGI
    Official Full Name
    zinc finger protein, autosomal, pseudogeneprovided by MGI
    Primary source
    MGI:MGI:99153
    See related
    Ensembl:ENSMUSG00000121690 AllianceGenome:MGI:99153
    Gene type
    pseudo
    RefSeq status
    VALIDATED
    Organism
    Mus musculus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
    Also known as
    Zfa; Zfx
    Summary
    Predicted to enable DNA-binding transcription factor activity, RNA polymerase II-specific and sequence-specific DNA binding activity. Predicted to be involved in regulation of transcription by RNA polymerase II. Predicted to be active in nucleus. Is expressed in testis. [provided by Alliance of Genome Resources, Apr 2022]
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    Genomic context

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    Location:
    10 B3; 10 26.71 cM
    Exon count:
    1
    Annotation release Status Assembly Chr Location
    RS_2024_02 current GRCm39 (GCF_000001635.27) 10 NC_000076.7 (52418416..52421835, complement)
    108.20200622 previous assembly GRCm38.p6 (GCF_000001635.26) 10 NC_000076.6 (52542320..52545739, complement)

    Chromosome 10 - NC_000076.7Genomic Context describing neighboring genes Neighboring gene STARR-positive B cell enhancer ABC_E2933 Neighboring gene NUS1 dehydrodolichyl diphosphate synthase subunit Neighboring gene STARR-seq mESC enhancer starr_26679 Neighboring gene STARR-seq mESC enhancer starr_26680 Neighboring gene STARR-seq mESC enhancer starr_26681 Neighboring gene predicted gene, 47612 Neighboring gene predicted gene, 36065 Neighboring gene STARR-seq mESC enhancer starr_26682 Neighboring gene solute carrier family 35, member F1 Neighboring gene VISTA enhancer mm782 Neighboring gene STARR-seq mESC enhancer starr_26684 Neighboring gene predicted gene, 36123

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Retroposon compensatory mechanism hypothesis not supported: Zfa knockout mice are fertile. Banks KG, et al. Genomics, 2003 Sep. PMID 12906850
    2. The musculus-type Y chromosome of the laboratory mouse is of Asian origin. Nagamine CM, et al. Mamm Genome, 1992. PMID 1352158
    3. Gene expression, X-inactivation, and methylation during spermatogenesis: the case of Zfa, Zfx, and Zfy in mice. Erickson RP, et al. Mol Reprod Dev, 1993 Jun. PMID 8318216
    4. Unexpected embryonic stem (ES) cell mutations represent a concern in gene targeting: lessons from "fierce" mice. Kumar RA, et al. Genesis, 2004 Feb. PMID 14994267
    5. Differential rates of evolution for the ZFY-related zinc finger genes, Zfy, Zfx, and Zfa in the mouse genus Mus. Tucker PK, et al. Mol Biol Evol, 2003 Jun. PMID 12716983

    See all (30) citations in PubMed

    GeneRIFs: Gene References Into Functions

    Variation

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    Alleles

    Alleles of this type are documented at Mouse Genome Informatics  (MGI)

    Interactions

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    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

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    Markers

    Other Names

    • zinc finger protein X-linked pseudogene
    • zinc finger protein ZFX

    Gene Ontology Provided by MGI

    Function Evidence Code Pubs
    enables DNA-binding transcription activator activity, RNA polymerase II-specific ISO
    Inferred from Sequence Orthology
    more info
    		  
    enables DNA-binding transcription factor activity, RNA polymerase II-specific IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    enables RNA polymerase II cis-regulatory region sequence-specific DNA binding ISO
    Inferred from Sequence Orthology
    more info
    		  
    enables sequence-specific DNA binding IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    Process Evidence Code Pubs
    involved_in positive regulation of transcription by RNA polymerase II ISO
    Inferred from Sequence Orthology
    more info
    		  
    involved_in regulation of transcription by RNA polymerase II IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    Component Evidence Code Pubs
    part_of chromatin ISO
    Inferred from Sequence Orthology
    more info
    		  
    located_in nucleolus ISO
    Inferred from Sequence Orthology
    more info
    		  
    located_in nucleoplasm ISO
    Inferred from Sequence Orthology
    more info
    		  
    is_active_in nucleus IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  

    NCBI Reference Sequences (RefSeq)

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    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    RNA

    1. NR_037920.1 RNA Sequence

      Status: VALIDATED

      Source sequence(s)
      AC153948
      Related
      ENSMUST00000180673.2

    RefSeqs of Annotated Genomes: GCF_000001635.27-RS_2024_02

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCm39 C57BL/6J

    Genomic

    1. NC_000076.7 Reference GRCm39 C57BL/6J

      Range
      52418416..52421835 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    Suppressed Reference Sequence(s)

    The following Reference Sequences have been suppressed. Explain

    1. NM_009540.3: Suppressed sequence

      Description
      NM_009540.3: This RefSeq was permanently suppressed because it is now thought that this gene is a transcribed pseudogene.
    Nucleotide Protein Strain
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    P23607.1 GenPept UniProtKB/Swiss-Prot:P23607

    Gene LinkOut

    The following LinkOut resources are supplied by external providers. These providers are responsible for maintaining the links.