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Tex35 testis expressed 35 [ Mus musculus (house mouse) ]

Gene ID: 73435, updated on 3-Apr-2024

Summary

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Official Symbol
Tex35provided by MGI
Official Full Name
testis expressed 35provided by MGI
Primary source
MGI:MGI:1920685
See related
Ensembl:ENSMUSG00000026592 AllianceGenome:MGI:1920685
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Mus musculus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
Also known as
1700057K13Rik
Summary
Located in nucleus. Orthologous to human TEX35 (testis expressed 35). [provided by Alliance of Genome Resources, Apr 2022]
Expression
Restricted expression toward testis adult (RPKM 77.3) See more
Orthologs
human all
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Genomic context

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Location:
1 H1; 1 67.97 cM
Exon count:
13
Annotation release Status Assembly Chr Location
RS_2024_02 current GRCm39 (GCF_000001635.27) 1 NC_000067.7 (156926711..156938506, complement)
108.20200622 previous assembly GRCm38.p6 (GCF_000001635.26) 1 NC_000067.6 (157099141..157108680, complement)

Chromosome 1 - NC_000067.7Genomic Context describing neighboring genes Neighboring gene STARR-seq mESC enhancer starr_02758 Neighboring gene STARR-positive B cell enhancer ABC_E5828 Neighboring gene STARR-positive B cell enhancer ABC_E4364 Neighboring gene STARR-seq mESC enhancer starr_02759 Neighboring gene STARR-positive B cell enhancer ABC_E2573 Neighboring gene STARR-positive B cell enhancer ABC_E3318 Neighboring gene predicted gene, 39685 Neighboring gene STARR-positive B cell enhancer ABC_E1569 Neighboring gene STARR-positive B cell enhancer mm9_chr1:158957909-158958210 Neighboring gene STARR-seq mESC enhancer starr_02761 Neighboring gene STARR-positive B cell enhancer ABC_E7762 Neighboring gene STARR-positive B cell enhancer ABC_E1232 Neighboring gene STARR-seq mESC enhancer starr_02762 Neighboring gene STARR-positive B cell enhancer ABC_E7763 Neighboring gene predicted gene, 30568 Neighboring gene predicted gene, 30694 Neighboring gene RAS protein activator like 2 Neighboring gene predicted gene, 51654

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Expression

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  • Project title: Mouse ENCODE transcriptome data
  • Description: RNA profiling data sets generated by the Mouse ENCODE project.
  • BioProject: PRJNA66167
  • Publication: PMID 25409824
  • Analysis date: n/a

Bibliography

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Related articles in PubMed

  1. Identification and characteristics of a novel testis-specific gene, Tsc24, in human and mice. Tang A, et al. Biol Pharm Bull, 2006 Nov. PMID 17077512
  2. CRISPR/Cas9-mediated genome editing reveals 30 testis-enriched genes dispensable for male fertility in mice†. Lu Y, et al. Biol Reprod, 2019 Aug 1. PMID 31201419, Free PMC Article
  3. Database resources of the National Center for Biotechnology Information. Wheeler DL, et al. Nucleic Acids Res, 2001 Jan 1. PMID 11125038, Free PMC Article
  4. A conditional knockout resource for the genome-wide study of mouse gene function. Skarnes WC, et al. Nature, 2011 Jun 15. PMID 21677750, Free PMC Article
  5. Wnk1 kinase deficiency lowers blood pressure in mice: a gene-trap screen to identify potential targets for therapeutic intervention. Zambrowicz BP, et al. Proc Natl Acad Sci U S A, 2003 Nov 25. PMID 14610273, Free PMC Article

See all (15) citations in PubMed

GeneRIFs: Gene References Into Functions

Variation

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Alleles

Alleles of this type are documented at Mouse Genome Informatics  (MGI)

General gene information

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Markers

Homology

Clone Names

  • MGC118391, MGC144290

Gene Ontology Provided by MGI

Function Evidence Code Pubs
enables molecular_function ND
No biological Data available
more info
  
Process Evidence Code Pubs
involved_in biological_process ND
No biological Data available
more info
  
Component Evidence Code Pubs
located_in microtubule cytoskeleton ISO
Inferred from Sequence Orthology
more info
  
is_active_in nucleus IBA
Inferred from Biological aspect of Ancestor
more info
  
located_in nucleus IDA
Inferred from Direct Assay
more info
 PubMed 

General protein information

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Preferred Names
testis-expressed protein 35
Names
testis-expressed sequence 35 protein
testis-specific conserved protein of 24 kDa

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001305059.1 → NP_001291988.1  testis-expressed protein 35 isoform 2

    See identical proteins and their annotated locations for NP_001291988.1

    Status: VALIDATED

    Source sequence(s)
    AK006825, CJ232085
    Consensus CDS
    CCDS78718.1
    UniProtKB/Swiss-Prot
    Q14BK3, Q4KKY9, Q9D9J9
    UniProtKB/TrEMBL
    A0A0R4J070
    Related
    ENSMUSP00000027884.7, ENSMUST00000027884.13
    Conserved Domains (1) summary
    pfam15079
    Location:1 → 194
    Tsc35; Testis-specific protein 35

  2. NM_001305061.1 → NP_001291990.1  testis-expressed protein 35 isoform 3

    See identical proteins and their annotated locations for NP_001291990.1

    Status: VALIDATED

    Source sequence(s)
    AC119220, AK006825, BY706810, CJ232085
    Consensus CDS
    CCDS78716.1
    UniProtKB/Swiss-Prot
    Q14BK3, Q4KKY9, Q9D9J9
    UniProtKB/TrEMBL
    D3Z4U7
    Conserved Domains (1) summary
    pfam15079
    Location:1 → 172
    Tsc35; Testis-specific protein 35

  3. NM_001305062.1 → NP_001291991.1  testis-expressed protein 35 isoform 3

    See identical proteins and their annotated locations for NP_001291991.1

    Status: VALIDATED

    Source sequence(s)
    AC119220, AK006825, BY080014, CJ232085
    Consensus CDS
    CCDS78716.1
    UniProtKB/Swiss-Prot
    Q14BK3, Q4KKY9, Q9D9J9
    UniProtKB/TrEMBL
    D3Z4U7
    Related
    ENSMUSP00000113622.2, ENSMUST00000121911.8
    Conserved Domains (1) summary
    pfam15079
    Location:1 → 172
    Tsc35; Testis-specific protein 35

  4. NM_001305063.1 → NP_001291992.1  testis-expressed protein 35 isoform 4

    Status: VALIDATED

    Source sequence(s)
    AC119220, AK006825, BY080014, CJ232085
    Consensus CDS
    CCDS78715.1
    UniProtKB/Swiss-Prot
    Q14BK3, Q4KKY9, Q9D9J9
    UniProtKB/TrEMBL
    D3Z652
    Related
    ENSMUSP00000113325.2, ENSMUST00000119526.2
    Conserved Domains (1) summary
    pfam15079
    Location:1 → 173
    Tsc35; Testis-specific protein 35

  5. NM_001374637.1 → NP_001361566.1  testis-expressed protein 35 isoform 5

    Status: VALIDATED

    Source sequence(s)
    AC119220
    Consensus CDS
    CCDS87897.1
    UniProtKB/Swiss-Prot
    Q14BK3, Q4KKY9, Q9D9J9
    UniProtKB/TrEMBL
    A0A087WNR4
    Related
    ENSMUSP00000139460.2, ENSMUST00000187546.7
    Conserved Domains (1) summary
    pfam15079
    Location:1 → 179
    Tsc35; Testis-specific protein 35

  6. NM_001400230.1 → NP_001387159.1  testis-expressed protein 35 isoform 6

    Status: VALIDATED

    Source sequence(s)
    AC119220

  7. NM_001400232.1 → NP_001387161.1  testis-expressed protein 35 isoform 7

    Status: VALIDATED

    Source sequence(s)
    AC119220

  8. NM_001400233.1 → NP_001387162.1  testis-expressed protein 35 isoform 4

    Status: VALIDATED

    Source sequence(s)
    AC119220
    UniProtKB/TrEMBL
    D3Z652

  9. NM_028540.3 → NP_082816.1  testis-expressed protein 35 isoform 1

    See identical proteins and their annotated locations for NP_082816.1

    Status: VALIDATED

    Source sequence(s)
    AC119220, AK006825, BY706810, CJ232085
    Consensus CDS
    CCDS48407.1
    UniProtKB/Swiss-Prot
    Q14BK3, Q4KKY9, Q9D9J9
    UniProtKB/TrEMBL
    A0A0R4J1P6
    Related
    ENSMUSP00000114092.2, ENSMUST00000118207.8
    Conserved Domains (1) summary
    pfam15079
    Location:1 → 193
    Tsc35; Testis-specific protein 35

RefSeqs of Annotated Genomes: GCF_000001635.27-RS_2024_02

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCm39 C57BL/6J

Genomic

  1. NC_000067.7 Reference GRCm39 C57BL/6J

    Range
    156926711..156938506 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_036153771.1 → XP_036009664.1  testis-expressed protein 35 isoform X2

    Conserved Domains (1) summary
    pfam15079
    Location:1 → 154
    Tsc35; Testis-specific protein 35

  2. XM_017312462.3 → XP_017167951.1  testis-expressed protein 35 isoform X2

    Conserved Domains (1) summary
    pfam15079
    Location:1 → 154
    Tsc35; Testis-specific protein 35

  3. XM_017312459.1 → XP_017167948.1  testis-expressed protein 35 isoform X2

    Conserved Domains (1) summary
    pfam15079
    Location:1 → 154
    Tsc35; Testis-specific protein 35

  4. XM_017312460.1 → XP_017167949.1  testis-expressed protein 35 isoform X2

    Conserved Domains (1) summary
    pfam15079
    Location:1 → 154
    Tsc35; Testis-specific protein 35
Nucleotide Protein Strain
Heading Accession and Version
Protein Accession Links
GenPept Link UniProtKB Link
Q14BK3.1 GenPept UniProtKB/Swiss-Prot:Q14BK3

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