APEX2 apurinic/apyrimidinic endodeoxyribonuclease 2 [Macaca mulatta (Rhesus monkey)] - Gene

Summary

Official Symbol: APEX2provided by VGNC
Official Full Name: apurinic/apyrimidinic endodeoxyribonuclease 2provided by VGNC
Primary source: VGNC:VGNC:69857
See related: Ensembl:ENSMMUG00000008428
Gene type: protein coding
RefSeq status: PROVISIONAL
Organism: Macaca mulatta
Lineage: Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Cercopithecidae; Cercopithecinae; Macaca
Orthologs: human mouse all
NEW: Try the new Gene table
Try the new Transcript table

Genomic context

Location:: chromosome: X

Exon count:: 6

Annotation release	Status	Assembly	Chr	Location
103	current	Mmul_10 (GCF_003339765.1)	X	NC_041774.1 (54727151..54734404)
102	previous assembly	Mmul_8.0.1 (GCF_000772875.2)	X	NC_027913.1 (54418794..54426047)

Chromosome X - NC_041774.1 Genomic Context describing neighboring genes

Genomic regions, transcripts, and products

Go to the top of the page Help

Go to reference sequence details

Genomic Sequence:

Go to nucleotide: Graphics FASTA GenBank

Bibliography

Go to the top of the page Help

GeneRIFs: Gene References Into Functions

What's a GeneRIF?

Submit: New GeneRIF Correction

General gene information

Go to the top of the page Help

Markers

APEX2_705 (e-PCR)
- UniSTS:276998

APEX2_V75 (e-PCR)
- UniSTS:276998

MARC_5951-5952:997299472:1 (e-PCR)
- UniSTS:269620

Gene Ontology Provided by RefSeq

Function	Evidence Code	Pubs
enables DNA binding	IEA Inferred from Electronic Annotation more info	PubMed
enables DNA-(apurinic or apyrimidinic site) endonuclease activity	IEA Inferred from Electronic Annotation more info	PubMed
enables double-stranded DNA 3'-5' DNA exonuclease activity	IEA Inferred from Electronic Annotation more info	PubMed
enables endonuclease activity	IEA Inferred from Electronic Annotation more info	PubMed
enables phosphoric diester hydrolase activity	IEA Inferred from Electronic Annotation more info	PubMed
enables zinc ion binding	IEA Inferred from Electronic Annotation more info	PubMed

Process	Evidence Code	Pubs
involved_in base-excision repair	IEA Inferred from Electronic Annotation more info	PubMed

Component	Evidence Code	Pubs
located_in nucleus	IEA Inferred from Electronic Annotation more info	PubMed

General protein information

Go to the top of the page Help

Preferred Names: DNA-(apurinic or apyrimidinic site) endonuclease 2

Names: DNA-(apurinic or apyrimidinic site) lyase 2

NP_001248294.1

EC 4.2.99.18

NCBI Reference Sequences (RefSeq)

Go to the top of the page Help

NEW Try the new Transcript table

RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

NM_001261365.1 → NP_001248294.1 DNA-(apurinic or apyrimidinic site) endonuclease 2

See identical proteins and their annotated locations for NP_001248294.1

Status: PROVISIONAL

Source sequence(s)

JV045278

UniProtKB/TrEMBL

F6VBU4, G7NRI7

Related

ENSMMUP00000011049.2, ENSMMUT00000011782.4

Conserved Domains (2) summary

cd09088
Location:3 → 311

Ape2-like_AP-endo; Human Ape2-like subfamily of the ExoIII family purinic/apyrimidinic (AP) endonucleases

pfam06839
Location:467 → 514

zf-GRF; GRF zinc finger