U.S. flag

An official website of the United States government

Format

Send to:

Choose Destination

adam19 ADAM metallopeptidase domain 19 [ Xenopus tropicalis (tropical clawed frog) ]

Gene ID: 677730, updated on 2-May-2024

Summary

Go to the top of the page Help
Official Symbol
adam19provided by Xenbase
Official Full Name
ADAM metallopeptidase domain 19provided by Xenbase
Primary source
Xenbase:XB-GENE-993485
See related
Ensembl:ENSXETG00000034170
Gene type
protein coding
RefSeq status
PROVISIONAL
Organism
Xenopus tropicalis
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Amphibia; Batrachia; Anura; Pipoidea; Pipidae; Xenopodinae; Xenopus; Silurana
Also known as
mltnb; fksg34; maddam
Orthologs
human mouse all
NEW
Try the new Gene table
Try the new Transcript table

Genomic context

Go to the top of the page Help
Location:
chromosome: 3
Exon count:
22
Annotation release Status Assembly Chr Location
104 current UCB_Xtro_10.0 (GCF_000004195.4) 3 NC_030679.2 (14003233..14041035, complement)
103 previous assembly Xenopus_tropicalis_v9.1 (GCF_000004195.3) 3 NC_030679.1 (6546626..6585530)

Chromosome 3 - NC_030679.2Genomic Context describing neighboring genes Neighboring gene clathrin interactor 1 Neighboring gene LSM11, U7 small nuclear RNA associated Neighboring gene NIPA-like domain containing 4 Neighboring gene cytoplasmic FMR1 interacting protein 2

Genomic regions, transcripts, and products

Go to the top of the page Help

Go to nucleotide: Graphics FASTA GenBank

Bibliography

Go to the top of the pageHelp

Related articles in PubMed

  1. Xenopus ADAM19 regulates Wnt signaling and neural crest specification by stabilizing ADAM13. Li J, et al. Development, 2018 Apr 4. PMID 29540504, Free PMC Article

GeneRIFs: Gene References Into Functions

General gene information

Go to the top of the page Help

Homology

Gene Ontology Provided by Xenbase

Function Evidence Code Pubs
enables metal ion binding IEA
Inferred from Electronic Annotation
more info
  
enables metalloendopeptidase activity IEA
Inferred from Electronic Annotation
more info
  
enables metallopeptidase activity IEA
Inferred from Electronic Annotation
more info
  
Process Evidence Code Pubs
acts_upstream_of_or_within proteolysis IEA
Inferred from Electronic Annotation
more info
  
Component Evidence Code Pubs
located_in membrane IEA
Inferred from Electronic Annotation
more info
  

General protein information

Go to the top of the page Help
Preferred Names
disintegrin and metalloproteinase domain-containing protein 19
Names
ADAM metallopeptidase domain 19 (meltrin beta)

NCBI Reference Sequences (RefSeq)

Go to the top of the page Help

NEW Try the new Transcript table

RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001040016.1 → NP_001035105.1  disintegrin and metalloproteinase domain-containing protein 19 precursor

    See identical proteins and their annotated locations for NP_001035105.1

    Status: PROVISIONAL

    Source sequence(s)
    DQ393789
    UniProtKB/TrEMBL
    A0A6I8SUW5, Q27JK5
    Related
    ENSXETP00000098610.2, ENSXETT00000091102.2
    Conserved Domains (5) summary
    smart00050
    Location:424 → 498
    DISIN; Homologues of snake disintegrins
    smart00608
    Location:500 → 642
    ACR; ADAM Cysteine-Rich Domain
    cd04269
    Location:211 → 405
    ZnMc_adamalysin_II_like; Zinc-dependent metalloprotease; adamalysin_II_like subfamily. Adamalysin II is a snake venom zinc endopeptidase. This subfamily contains other snake venom metalloproteinases, as well as membrane-anchored metalloproteases belonging to the ADAM family. ...
    pfam01421
    Location:211 → 407
    Reprolysin; Reprolysin (M12B) family zinc metalloprotease
    pfam01562
    Location:63 → 163
    Pep_M12B_propep; Reprolysin family propeptide

RefSeqs of Annotated Genomes: Xenopus tropicalis Annotation Release 104 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference UCB_Xtro_10.0 Primary Assembly

Genomic

  1. NC_030679.2 Reference UCB_Xtro_10.0 Primary Assembly

    Range
    14003233..14041035 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_031897992.1 → XP_031753852.1  disintegrin and metalloproteinase domain-containing protein 19 isoform X1

    UniProtKB/TrEMBL
    A0A6I8PWV8, A0A6I8SUW5
    Related
    ENSXETP00000058560.3, ENSXETT00000061893.3
    Conserved Domains (4) summary
    smart00050
    Location:402 → 476
    DISIN; Homologues of snake disintegrins
    smart00608
    Location:478 → 620
    ACR; ADAM Cysteine-Rich Domain
    pfam01421
    Location:197 → 385
    Reprolysin; Reprolysin (M12B) family zinc metalloprotease
    pfam01562
    Location:43 → 164
    Pep_M12B_propep; Reprolysin family propeptide
Nucleotide Protein Strain
Heading Accession and Version

Gene LinkOut

The following LinkOut resources are supplied by external providers. These providers are responsible for maintaining the links.