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AFF2 ALF transcription elongation factor 2 [ Bos taurus (cattle) ]

Gene ID: 522215, updated on 5-Mar-2024

Summary

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Official Symbol
AFF2provided by VGNC
Official Full Name
ALF transcription elongation factor 2provided by VGNC
Primary source
VGNC:VGNC:25711
See related
Ensembl:ENSBTAG00000020750
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Bos taurus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Laurasiatheria; Artiodactyla; Ruminantia; Pecora; Bovidae; Bovinae; Bos
Orthologs
human mouse all
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Genomic context

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Location:
chromosome: X
Exon count:
24
Annotation release Status Assembly Chr Location
RS_2023_09 current ARS-UCD2.0 (GCF_002263795.3) X NC_037357.1 (31117344..31651657)

Chromosome X - NC_037357.1Genomic Context describing neighboring genes Neighboring gene proteasome subunit beta type-6-like Neighboring gene microRNA mir-11988 Neighboring gene FMR1 neighbor Neighboring gene pre-rRNA-processing protein TSR2 homolog Neighboring gene U2 spliceosomal RNA

Genomic regions, transcripts, and products

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Genomic Sequence:
NC_037357.1 Chromosome X Reference ARS-UCD2.0 Primary Assembly

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. A whole-genome assembly of the domestic cow, Bos taurus. Zimin AV, et al. Genome Biol, 2009. PMID 19393038, Free PMC Article

GeneRIFs: Gene References Into Functions

General gene information

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Markers

Homology

Gene Ontology Provided by RefSeq

Function Evidence Code Pubs
enables G-quadruplex RNA binding IEA
Inferred from Electronic Annotation
more info
 PubMed 
Process Evidence Code Pubs
involved_in regulation of RNA splicing IEA
Inferred from Electronic Annotation
more info
 PubMed 
Component Evidence Code Pubs
located_in nuclear speck IEA
Inferred from Electronic Annotation
more info
 PubMed 
located_in nucleus IEA
Inferred from Electronic Annotation
more info
 PubMed 

General protein information

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Preferred Names
AF4/FMR2 family member 2

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001191543.2 → NP_001178472.1  AF4/FMR2 family member 2

    Status: VALIDATED

    Source sequence(s)
    NKLS02000030
    UniProtKB/TrEMBL
    E1BP77
    Related
    ENSBTAP00000053415.3, ENSBTAT00000061034.4
    Conserved Domains (1) summary
    pfam05110
    Location:19 → 1267
    AF-4; AF-4 proto-oncoprotein

RefSeqs of Annotated Genomes: GCF_002263795.3-RS_2023_09

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference ARS-UCD2.0 Primary Assembly

Genomic

  1. NC_037357.1 Reference ARS-UCD2.0 Primary Assembly

    Range
    31117344..31651657
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_024988032.2 → XP_024843800.1  AF4/FMR2 family member 2 isoform X1

    Conserved Domains (1) summary
    pfam05110
    Location:19 → 1328
    AF-4; AF-4 proto-oncoprotein

  2. XM_024988034.2 → XP_024843802.1  AF4/FMR2 family member 2 isoform X3

    Conserved Domains (1) summary
    pfam05110
    Location:19 → 1299
    AF-4; AF-4 proto-oncoprotein

  3. XM_059883420.1 → XP_059739403.1  AF4/FMR2 family member 2 isoform X6

  4. XM_059883421.1 → XP_059739404.1  AF4/FMR2 family member 2 isoform X8

  5. XM_024988033.2 → XP_024843801.1  AF4/FMR2 family member 2 isoform X2

    Conserved Domains (1) summary
    pfam05110
    Location:19 → 1324
    AF-4; AF-4 proto-oncoprotein

  6. XM_005227590.5 → XP_005227647.1  AF4/FMR2 family member 2 isoform X4

    Conserved Domains (1) summary
    pfam05110
    Location:19 → 1296
    AF-4; AF-4 proto-oncoprotein

  7. XM_005227592.5 → XP_005227649.1  AF4/FMR2 family member 2 isoform X7

    Conserved Domains (1) summary
    pfam05110
    Location:19 → 1263
    AF-4; AF-4 proto-oncoprotein

  8. XM_005227591.5 → XP_005227648.1  AF4/FMR2 family member 2 isoform X5

    Related
    ENSBTAP00000097479.1, ENSBTAT00000110279.1
    Conserved Domains (1) summary
    pfam05110
    Location:19 → 1292
    AF-4; AF-4 proto-oncoprotein

  9. XM_024988036.2 → XP_024843804.1  AF4/FMR2 family member 2 isoform X9

    Conserved Domains (1) summary
    pfam05110
    Location:1 → 1248
    AF-4; AF-4 proto-oncoprotein

  10. XM_024988035.2 → XP_024843803.1  AF4/FMR2 family member 2 isoform X9

    Conserved Domains (1) summary
    pfam05110
    Location:1 → 1248
    AF-4; AF-4 proto-oncoprotein
Nucleotide Protein Strain
Heading Accession and Version

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