ARHGAP23 Rho GTPase activating protein 23 [Canis lupus familiaris (dog)] - Gene

Summary

Official Symbol: ARHGAP23provided by VGNC
Official Full Name: Rho GTPase activating protein 23provided by VGNC
Primary source: VGNC:VGNC:38052
See related: Ensembl:ENSCAFG00845014513
Gene type: protein coding
RefSeq status: MODEL
Organism: Canis lupus familiaris (sub-species: familiaris)
Lineage: Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Laurasiatheria; Carnivora; Caniformia; Canidae; Canis
Orthologs: human mouse all
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Genomic context

Location:: chromosome: 9

Exon count:: 24

Annotation release	Status	Assembly	Chr	Location
106	current	ROS_Cfam_1.0 (GCF_014441545.1)	9	NC_051813.1 (24473264..24545593, complement)
106	current	Dog10K_Boxer_Tasha (GCF_000002285.5)	9	NC_006591.4 (23147673..23219960, complement)
106	current	UU_Cfam_GSD_1.0 (GCF_011100685.1)	9	NC_049230.1 (23632017..23704279, complement)
106	current	UMICH_Zoey_3.1 (GCF_005444595.1)	9	NC_049269.1 (23244385..23316649, complement)
106	current	UNSW_CanFamBas_1.0 (GCF_013276365.1)	9	NC_049750.1 (23506033..23577714, complement)

Chromosome 9 - NC_051813.1 Genomic Context describing neighboring genes

Genomic regions, transcripts, and products

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Genomic Sequence:

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Bibliography

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GeneRIFs: Gene References Into Functions

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General gene information

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Homology

NCBI Orthologs

Orthologs from OrthoDB

Gene Ontology Provided by RefSeq

Function	Evidence Code	Pubs
enables protein binding	IEA Inferred from Electronic Annotation more info	PubMed

Process	Evidence Code	Pubs
involved_in signal transduction	IEA Inferred from Electronic Annotation more info	PubMed

General protein information

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Preferred Names: rho GTPase-activating protein 23; LOW QUALITY PROTEIN: rho GTPase-activating protein 23

NCBI Reference Sequences (RefSeq)

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RefSeqs of Annotated Genomes: Canis lupus familiaris Annotation Release 106 details...

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference ROS_Cfam_1.0

Genomic

NC_051813.1 Reference ROS_Cfam_1.0

Range

24473264..24545593 complement

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GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

XM_038676682.1 → XP_038532610.1 rho GTPase-activating protein 23 isoform X1

UniProtKB/TrEMBL

A0A8C0LEY9

Related

ENSCAFP00845020522.1, ENSCAFT00845026028.1

Conserved Domains (4) summary

PHA03247
Location:191 → 584

PHA03247; large tegument protein UL36; Provisional

cd00992
Location:41 → 157

PDZ_signaling; PDZ domain found in a variety of Eumetazoan signaling molecules, often in tandem arrangements. May be responsible for specific protein-protein interactions, as most PDZ domains bind C-terminal polypeptides, and binding to internal (non-C-terminal) ...

cd04395
Location:908 → 1103

RhoGAP_ARHGAP21; RhoGAP (GTPase-activator protein [GAP] for Rho-like small GTPases) domain of ArhGAP21-like proteins. ArhGAP21 is a multi-domain protein, containing RhoGAP, PH and PDZ domains, and is believed to play a role in the organization of the cell-cell junction ...

cd01253
Location:696 → 816

PH_ARHGAP21-like; ARHGAP21 and related proteins pleckstrin homology (PH) domain

Alternate UMICH_Zoey_3.1

Genomic

NC_049269.1 Alternate UMICH_Zoey_3.1

Range

23244385..23316649 complement

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GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

XM_038485736.1 → XP_038341664.1 LOW QUALITY PROTEIN: rho GTPase-activating protein 23 isoform X1

Alternate UNSW_CanFamBas_1.0

Genomic

NC_049750.1 Alternate UNSW_CanFamBas_1.0

Range

23506033..23577714 complement

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GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

XM_038611489.1 → XP_038467417.1 LOW QUALITY PROTEIN: rho GTPase-activating protein 23 isoform X2

Alternate UU_Cfam_GSD_1.0

Genomic

NC_049230.1 Alternate UU_Cfam_GSD_1.0

Range

23632017..23704279 complement

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GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

XM_038547507.1 → XP_038403435.1 LOW QUALITY PROTEIN: rho GTPase-activating protein 23 isoform X1

UniProtKB/TrEMBL

A0A8C0LEY9

Alternate Dog10K_Boxer_Tasha Primary Assembly

Genomic

NC_006591.4 Alternate Dog10K_Boxer_Tasha Primary Assembly

Range

23147673..23219960 complement

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GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

XM_038604546.1 → XP_038460474.1 rho GTPase-activating protein 23 isoform X3

UniProtKB/TrEMBL

A0A8C0LEY9

Conserved Domains (4) summary

PHA03247
Location:192 → 585

PHA03247; large tegument protein UL36; Provisional

cd00992
Location:41 → 158

PDZ_signaling; PDZ domain found in a variety of Eumetazoan signaling molecules, often in tandem arrangements. May be responsible for specific protein-protein interactions, as most PDZ domains bind C-terminal polypeptides, and binding to internal (non-C-terminal) ...

cd04395
Location:909 → 1104

RhoGAP_ARHGAP21; RhoGAP (GTPase-activator protein [GAP] for Rho-like small GTPases) domain of ArhGAP21-like proteins. ArhGAP21 is a multi-domain protein, containing RhoGAP, PH and PDZ domains, and is believed to play a role in the organization of the cell-cell junction ...

cd01253
Location:697 → 817

PH_ARHGAP21-like; ARHGAP21 and related proteins pleckstrin homology (PH) domain