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ACRBP acrosin binding protein [ Sus scrofa (pig) ]

Gene ID: 397317, updated on 5-Mar-2024

Summary

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Official Symbol
ACRBPprovided by VGNC
Official Full Name
acrosin binding proteinprovided by VGNC
Primary source
VGNC:VGNC:85029
See related
Ensembl:ENSSSCG00000000700
Gene type
protein coding
RefSeq status
MODEL
Organism
Sus scrofa
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Laurasiatheria; Artiodactyla; Suina; Suidae; Sus
Also known as
sp32
Expression
Ubiquitous expression in spleen (RPKM 2.4), ovary (RPKM 1.8) and 8 other tissues See more
Orthologs
human mouse all
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Genomic context

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Location:
chromosome: 5
Exon count:
10
Annotation release Status Assembly Chr Location
106 current Sscrofa11.1 (GCF_000003025.6) 5 NC_010447.5 (64036810..64047846)
105 previous assembly Sscrofa10.2 (GCF_000003025.5) 5 NC_010447.4 (66530446..66541094, complement)

Chromosome 5 - NC_010447.5Genomic Context describing neighboring genes Neighboring gene zinc finger protein 384 Neighboring gene inhibitor of growth family member 4 Neighboring gene lysophosphatidic acid receptor 5 Neighboring gene chromodomain helicase DNA binding protein 4 Neighboring gene transcription initiation factor TFIID subunit 10 pseudogene

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Expression

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  • Project title: Transcriptome data used for gene annotation
  • Description: Nine kinds of tissues and a mixture of multiple tissues were sequenced for genome annotation
  • BioProject: PRJNA311523
  • Publication: PMID 27646534
  • Analysis date: Thu Dec 14 17:10:49 2017

Bibliography

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Related articles in PubMed

  1. Expression and tyrosine phosphorylation of sp32 regulate the activation of the boar proacrosin/acrosin system. Dong HT, et al. Genet Mol Res, 2015 Mar 27. PMID 25867384
  2. The proacrosin binding protein, sp32, is tyrosine phosphorylated during capacitation of pig sperm. Dubé C, et al. J Androl, 2005 Jul-Aug. PMID 15955892
  3. An acrosomal protein, sp32, in mammalian sperm is a binding protein specific for two proacrosins and an acrosin intermediate. Baba T, et al. J Biol Chem, 1994 Apr 1. PMID 8144514
  4. Transgenic pig carrying green fluorescent proteasomes. Miles EL, et al. Proc Natl Acad Sci U S A, 2013 Apr 16. PMID 23550158, Free PMC Article

GeneRIFs: Gene References Into Functions

What's a GeneRIF?
  1. Characterization of acrosin and acrosin binding protein as novel CRISP2 interacting proteins in boar spermatozoa.
    Title: Characterization of acrosin and acrosin binding protein as novel CRISP2 interacting proteins in boar spermatozoa.
  2. Data show that sperm protein 32 (sp32) expression was higher and significantly higher in capacitated and post-acrosomal reaction sperms than in frozen-thawed sperms and fresh semen, respectively.
    Title: Expression and tyrosine phosphorylation of sp32 regulate the activation of the boar proacrosin/acrosin system.
Submit: New GeneRIF Correction

Interactions

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Products Interactant Other Gene Complex Source Pubs Description

General gene information

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Markers

Homology

Gene Ontology Provided by RefSeq

Component Evidence Code Pubs
located_in acrosomal vesicle IEA
Inferred from Electronic Annotation
more info
 PubMed 
located_in nucleus IEA
Inferred from Electronic Annotation
more info
 PubMed 

General protein information

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Preferred Names
acrosin-binding protein
Names
Acrosin-binding protein

NCBI Reference Sequences (RefSeq)

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RefSeqs of Annotated Genomes: Sus scrofa Annotation Release 106 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference Sscrofa11.1 Primary Assembly

Genomic

  1. NC_010447.5 Reference Sscrofa11.1 Primary Assembly

    Range
    64036810..64047846
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_003126533.4 → XP_003126581.1  acrosin-binding protein

    UniProtKB/Swiss-Prot
    Q29016
    UniProtKB/TrEMBL
    A0A480WSQ6, A0A8D0JP05
    Related
    ENSSSCP00000076796.1, ENSSSCT00000092092.1
    Conserved Domains (1) summary
    pfam07222
    Location:26 → 210
    PBP_sp32; Proacrosin binding protein sp32
Nucleotide Protein
Heading Accession and Version
Protein Accession Links
GenPept Link UniProtKB Link
Q29016.2 GenPept UniProtKB/Swiss-Prot:Q29016

Gene LinkOut

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