Conserved Protein Domain Family
PBP_sp32
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pfam07222: PBP_sp32 (this model, PSSM-Id:311272 is obsolete and has been replaced by 429354)
Proacrosin binding protein sp32
This family consists of several mammalian specific proacrosin binding protein sp32 sequences. sp32 is a sperm specific protein which is known to bind with with 55- and 53-kDa proacrosins and the 49-kDa acrosin intermediate. The exact function of sp32 is unclear, it is thought however that the binding of sp32 to proacrosin may be involved in packaging the acrosin zymogen into the acrosomal matrix.
Links
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Statistics
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PSSM-Id: 311272
Aligned: 3 rows
Threshold Bit Score: 348.205
Created: 11-May-2020
Updated: 7-Aug-2020
Structure
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Aligned Rows:
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Sequence Alignment
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Format: Row Display: Color Bits: Type Selection: 
PNI21281   1 MRKPAAGFLPSLLKVLLLPLAPAAAQDSTQasTPGSPLSPTEYERFFALLTPTWKAETTCRLRATHGCRNPTLVQLDQYE 80  chimpanzee
AAI21693  31 TFRCFLQAILMLFIIILFKLSITTCEFSTP--LPGSPLNKQEYEKFFSLLISESSAETLCTLRYLHGCGDRTIRRFDAYE 108 tropical clawed frog
Q3V140     1 MMNLAAGFLLMLLEVLLLPGTPLSAEES-PasTPGSPLSSTEYERFFALLTPTWKAETTCRLRATHGCRNPTLVQLDQYE 79  house mouse

PNI21281  81 NHGLVPDGAVCSNLPYASWFESFCQFTHYRCSNHVYYAKRVLCS--QPVSILSPNTLKEIEASAEVSPTTMTSPISPHFT 158 chimpanzee
AAI21693 109 NHGVTPVGPICTNLESFSHFDSFCDFAKFRCAHRLFYAKRIPCEdhKVTTIQASDAMPKQEVQSVTSSLPAETPKITENG 188 tropical clawed frog
Q3V140    80 NHGLVPDGAVCSDLPYASWFESFCQFAQYRCSNHVYYAKRVRCS--QPVSILSPNTLKEVESSAEVPPTSMTTPIVSHAT 157 house mouse

PNI21281 159 VTERQtfqpwpERLSNNVEE-----LLQSSLSLggQEQAPE---HKQEQGVEHRQEPTQEHKQEEGQKQEEQEEEQ---E 227 chimpanzee
AAI21693 189 SSEKE------ERKLHSAEQkpmkaMYKSDESV--KVKAPHlakPKEKPLLSKLQAYLEAHPTARKKPVKEQNEEEvlkI 260 tropical clawed frog
Q3V140   158 ATEHQafqpwpERLNNNVEE-----LLQSSLSLggKDQQSSr-rPGQEQ---RKQEQIQEHKLEEAQEQEEQEEEEe--E 226 house mouse

PNI21281 228 EEGKQEEGQGTKE 240 chimpanzee
AAI21693 261 PYASQESSEGEDD 273 tropical clawed frog
Q3V140   227 EEAKQEEGQGT-E 238 house mouse
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