Asb9 ankyrin repeat and SOCS box-containing 9 [Rattus norvegicus (Norway rat)] - Gene

Summary

Official Symbol: Asb9provided by RGD
Official Full Name: ankyrin repeat and SOCS box-containing 9provided by RGD
Primary source: RGD:1560537
See related: Ensembl:ENSRNOG00000067365 AllianceGenome:RGD:1560537
Gene type: protein coding
RefSeq status: PROVISIONAL
Organism: Rattus norvegicus
Lineage: Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Rattus
Also known as: RGD1560537
Summary: Predicted to be involved in positive regulation of protein catabolic process and protein ubiquitination. Orthologous to human ASB9 (ankyrin repeat and SOCS box containing 9). [provided by Alliance of Genome Resources, Apr 2022]
Expression: Biased expression in Testes (RPKM 87.5) and Kidney (RPKM 47.6) See more
Orthologs: human mouse all
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Genomic context

Location:: Xq14

Exon count:: 8

Annotation release	Status	Assembly	Chr	Location
RS_2024_02	current	GRCr8 (GCF_036323735.1)	X	NC_086039.1 (33588484..33633285, complement)
RS_2023_06	previous assembly	mRatBN7.2 (GCF_015227675.2)	X	NC_051356.1 (29956576..30001436, complement)
106	previous assembly	Rnor_6.0 (GCF_000001895.5)	X	NC_005120.4 (31700637..31745790, complement)

Chromosome X - NC_086039.1 Genomic Context describing neighboring genes

Genomic regions, transcripts, and products

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Genomic Sequence:

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Expression

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See details

Project title: A rat RNA-Seq transcriptomic BodyMap across 11 organs and 4 developmental stages
Description: 320 RNA samples isolated from 11 organs (adrenal gland, brain, heart, kidney, liver, lung, muscle, spleen, thymus, and testes or uterus) from both sexes of Fischer 344 rats across four developmental stages (2-, 6-, 21-, and 104-weeks-old)
BioProject: PRJNA238328
Publication: PMID 24510058
Analysis date: Mon Jun 6 17:44:12 2016

Bibliography

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GeneRIFs: Gene References Into Functions

What's a GeneRIF?

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General gene information

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Gene Ontology Provided by RGD

Process	Evidence Code	Pubs
involved_in intracellular signal transduction	IEA Inferred from Electronic Annotation more info
involved_in positive regulation of protein catabolic process	IBA Inferred from Biological aspect of Ancestor more info
acts_upstream_of_or_within positive regulation of protein catabolic process	ISO Inferred from Sequence Orthology more info
involved_in protein ubiquitination	IBA Inferred from Biological aspect of Ancestor more info
involved_in protein ubiquitination	IEA Inferred from Electronic Annotation more info
acts_upstream_of_or_within protein ubiquitination	ISO Inferred from Sequence Orthology more info

Component	Evidence Code	Pubs
located_in membrane	IEA Inferred from Electronic Annotation more info

General protein information

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Preferred Names: ankyrin repeat and SOCS box protein 9

Names: ankyrin repeat and SOCS box-containing protein 9

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

NM_001191913.1 → NP_001178842.1 ankyrin repeat and SOCS box protein 9

See identical proteins and their annotated locations for NP_001178842.1

Status: PROVISIONAL

Source sequence(s)

JAXUCZ010000021

UniProtKB/TrEMBL

F1M6U5

Conserved Domains (4) summary

PLN03192
Location:27 → 214

PLN03192; Voltage-dependent potassium channel; Provisional

sd00045
Location:31 → 62

ANK; ANK repeat [structural motif]

pfam12796
Location:36 → 122

Ank_2; Ankyrin repeats (3 copies)

cl02533
Location:249 → 290

SOCS; SOCS (suppressors of cytokine signaling) box. The SOCS box is found in the C-terminal region of CIS/SOCS family proteins (in combination with a SH2 domain), ASBs (ankyrin repeat-containing proteins with a SOCS box), SSBs (SPRY domain-containing proteins ...

RefSeqs of Annotated Genomes: GCF_036323735.1-RS_2024_02

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCr8

Genomic

NC_086039.1 Reference GRCr8

Range

33588484..33633285 complement

Download

GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

XM_017602120.3 → XP_017457609.1 ankyrin repeat and SOCS box protein 9 isoform X1

UniProtKB/TrEMBL

F1M6U5

Related

ENSRNOP00000038983.6

Conserved Domains (4) summary

PLN03192
Location:27 → 214

PLN03192; Voltage-dependent potassium channel; Provisional

sd00045
Location:31 → 62

ANK; ANK repeat [structural motif]

pfam12796
Location:36 → 122

Ank_2; Ankyrin repeats (3 copies)

cl02533
Location:249 → 290

SOCS; SOCS (suppressors of cytokine signaling) box. The SOCS box is found in the C-terminal region of CIS/SOCS family proteins (in combination with a SH2 domain), ASBs (ankyrin repeat-containing proteins with a SOCS box), SSBs (SPRY domain-containing proteins ...