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Vmn2r10 vomeronasal 2, receptor 10 [ Mus musculus (house mouse) ]

Gene ID: 22307, updated on 11-Apr-2024

Summary

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Official Symbol
Vmn2r10provided by MGI
Official Full Name
vomeronasal 2, receptor 10provided by MGI
Primary source
MGI:MGI:1316730
See related
Ensembl:ENSMUSG00000067010 AllianceGenome:MGI:1316730
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Mus musculus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
Also known as
VR16; V2r16
Summary
Predicted to enable G protein-coupled receptor activity. Predicted to be integral component of plasma membrane. [provided by Alliance of Genome Resources, Apr 2022]
Expression
Low expression observed in reference dataset See more
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Genomic context

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Location:
5 F; 5 53.24 cM
Exon count:
7
Annotation release Status Assembly Chr Location
RS_2024_02 current GRCm39 (GCF_000001635.27) 5 NC_000071.7 (109141278..109154337, complement)
108.20200622 previous assembly GRCm38.p6 (GCF_000001635.26) 5 NC_000071.6 (108995539..109006436, complement)

Chromosome 5 - NC_000071.7Genomic Context describing neighboring genes Neighboring gene general transcription factor IIH, polypeptide 3 pseudogene Neighboring gene coiled-coil domain containing 77 pseudogene Neighboring gene STARR-seq mESC enhancer starr_13913 Neighboring gene predicted gene 5871 Neighboring gene STARR-seq mESC enhancer starr_13914 Neighboring gene vomeronasal 2, receptor 11

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Expression

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  • Project title: Mouse ENCODE transcriptome data
  • Description: RNA profiling data sets generated by the Mouse ENCODE project.
  • BioProject: PRJNA66167
  • Publication: PMID 25409824
  • Analysis date: n/a

Bibliography

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Related articles in PubMed

  1. A multigene family encoding a diverse array of putative pheromone receptors in mammals. Matsunami H, et al. Cell, 1997 Aug 22. PMID 9288756
  2. Disruption and sequence identification of 2,000 genes in mouse embryonic stem cells. Zambrowicz BP, et al. Nature, 1998 Apr 9. PMID 9560157
  3. V2R gene families degenerated in primates, dog and cow, but expanded in opossum. Young JM, et al. Trends Genet, 2007 May. PMID 17382427
  4. A high-resolution anatomical atlas of the transcriptome in the mouse embryo. Diez-Roux G, et al. PLoS Biol, 2011 Jan 18. PMID 21267068, Free PMC Article
  5. Analysis of the mouse transcriptome based on functional annotation of 60,770 full-length cDNAs. Okazaki Y, et al. Nature, 2002 Dec 5. PMID 12466851

See all (6) citations in PubMed

GeneRIFs: Gene References Into Functions

General gene information

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Markers

Homology

Gene Ontology Provided by MGI

Function Evidence Code Pubs
enables G protein-coupled receptor activity IBA
Inferred from Biological aspect of Ancestor
more info
  
Component Evidence Code Pubs
is_active_in plasma membrane IBA
Inferred from Biological aspect of Ancestor
more info
  

General protein information

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Preferred Names
vomeronasal 2, receptor, 16
Names
vomeronasal organ family 2, receptor, 16
vomeronasal receptor Vmn2r10

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001385035.1 → NP_001371964.1  vomeronasal 2, receptor, 16 isoform 2 precursor

    Status: VALIDATED

    Source sequence(s)
    AC133456
    Conserved Domains (3) summary
    cd15283
    Location:579 → 829
    7tmC_V2R_pheromone; vomeronasal type-2 pheromone receptors, member of the class C family of seven-transmembrane G protein-coupled receptors
    cd06365
    Location:45 → 498
    PBP1_pheromone_receptor; Ligand-binding domain of the V2R pheromone receptor, a member of the family C receptors within the G-protein coupled receptor superfamily
    pfam07562
    Location:506 → 559
    NCD3G; Nine Cysteines Domain of family 3 GPCR

  2. NM_009491.4 → NP_033517.3  vomeronasal 2, receptor, 16 isoform 1 precursor

    Status: VALIDATED

    Source sequence(s)
    AC133456
    Consensus CDS
    CCDS51596.1
    UniProtKB/TrEMBL
    K7N621
    Related
    ENSMUSP00000078162.4, ENSMUST00000079163.5
    Conserved Domains (3) summary
    cd06365
    Location:40 → 498
    PBP1_Pheromone_receptor; Ligand-binding domain of the V2R phermone receptor, a member of the family C receptors within the G-protein coupled receptor superfamily
    pfam00003
    Location:594 → 828
    7tm_3; 7 transmembrane sweet-taste receptor of 3 GCPR
    pfam07562
    Location:508 → 559
    NCD3G; Nine Cysteines Domain of family 3 GPCR

RNA

  1. NR_169559.1 RNA Sequence

    Status: VALIDATED

    Source sequence(s)
    AC133456

RefSeqs of Annotated Genomes: GCF_000001635.27-RS_2024_02

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCm39 C57BL/6J

Genomic

  1. NC_000071.7 Reference GRCm39 C57BL/6J

    Range
    109141278..109154337 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_030254368.1 → XP_030110228.1  vomeronasal 2, receptor, 16 isoform X1

    Conserved Domains (3) summary
    cd15283
    Location:582 → 832
    7tmC_V2R_pheromone; vomeronasal type-2 pheromone receptors, member of the class C family of seven-transmembrane G protein-coupled receptors
    pfam07562
    Location:508 → 562
    NCD3G; Nine Cysteines Domain of family 3 GPCR
    cd06365
    Location:45 → 500
    PBP1_pheromone_receptor; Ligand-binding domain of the V2R pheromone receptor, a member of the family C receptors within the G-protein coupled receptor superfamily
Nucleotide Protein Strain
Heading Accession and Version

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