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dpy-21 Lysine-specific demethylase 9 [ Caenorhabditis elegans ]

Gene ID: 180176, updated on 23-Nov-2023

Summary

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Gene symbol
dpy-21
Gene description
Lysine-specific demethylase 9
Primary source
WormBase:WBGene00001080
Locus tag
CELE_Y59A8B.1
See related
AllianceGenome:WB:WBGene00001080
Gene type
protein coding
RefSeq status
REVIEWED
Organism
Caenorhabditis elegans (strain: Bristol N2)
Lineage
Eukaryota; Metazoa; Ecdysozoa; Nematoda; Chromadorea; Rhabditida; Rhabditina; Rhabditomorpha; Rhabditoidea; Rhabditidae; Peloderinae; Caenorhabditis
Summary
Predicted to enable dioxygenase activity and metal ion binding activity. Located in X chromosome. Orthologous to human RSBN1 (round spermatid basic protein 1) and RSBN1L (round spermatid basic protein 1 like). [provided by Alliance of Genome Resources, Apr 2022]
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Genomic context

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Location:
chromosome: V
Exon count:
11
Sequence:
Chromosome: V; NC_003283.11 (17936282..17949193, complement)

Chromosome V - NC_003283.11Genomic Context describing neighboring genes Neighboring gene USP domain-containing protein Neighboring gene tRNA Neighboring gene tRNA Neighboring gene ncRNA Neighboring gene ncRNA Neighboring gene Secreted protein Neighboring gene Germinal center kinase 3

Genomic regions, transcripts, and products

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Genomic Sequence:
NC_003283.11

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. Dynamic Control of Chromosome Topology and Gene Expression by a Chromatin Modification. Bian Q, et al. Cold Spring Harb Symp Quant Biol, 2017. PMID 29472317, Free PMC Article
  2. Genetic mapping of the 5S rRNA gene cluster of the nematode Caenorhabditis elegans. Nelson DW, et al. Can J Genet Cytol, 1986 Aug. PMID 3019494
  3. Dynamic Control of X Chromosome Conformation and Repression by a Histone H4K20 Demethylase. Brejc K, et al. Cell, 2017 Sep 21. PMID 28867287, Free PMC Article
  4. Unexpected role for dosage compensation in the control of dauer arrest, insulin-like signaling, and FoxO transcription factor activity in Caenorhabditis elegans. Dumas KJ, et al. Genetics, 2013 Jul. PMID 23733789, Free PMC Article
  5. Caenorhabditis elegans compensates for the difference in X chromosome dosage between the sexes by regulating transcript levels. Meyer BJ, et al. Cell, 1986 Dec 26. PMID 3779843

See all (65) citations in PubMed

GeneRIFs: Gene References Into Functions

Interactions

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Products Interactant Other Gene Complex Source Pubs Description

General gene information

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Markers

Homology

Gene Ontology Provided by WormBase

Function Evidence Code Pubs
enables dioxygenase activity IEA
Inferred from Electronic Annotation
more info
  
enables histone H4K20 demethylase activity IDA
Inferred from Direct Assay
more info
 PubMed 
enables metal ion binding IEA
Inferred from Electronic Annotation
more info
  
enables oxidoreductase activity IEA
Inferred from Electronic Annotation
more info
  
Process Evidence Code Pubs
involved_in chromatin remodeling IEA
Inferred from Electronic Annotation
more info
  
Component Evidence Code Pubs
located_in X chromosome IDA
Inferred from Direct Assay
more info
 PubMed 
located_in chromosome IEA
Inferred from Electronic Annotation
more info
  
is_active_in nucleus IBA
Inferred from Biological aspect of Ancestor
more info
  
located_in nucleus IEA
Inferred from Electronic Annotation
more info
  

General protein information

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Preferred Names
Lysine-specific demethylase 9
NP_001024266.1
  • Confirmed by transcript evidence

NCBI Reference Sequences (RefSeq)

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Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NC_003283.11 Reference assembly

    Range
    17936282..17949193 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. NM_001029095.4 → NP_001024266.1  Lysine-specific demethylase 9 [Caenorhabditis elegans]

    See identical proteins and their annotated locations for NP_001024266.1

    Status: REVIEWED

    UniProtKB/Swiss-Prot
    Q9GRZ3
    Conserved Domains (2) summary
    pfam09736
    Location:395 → 440
    Bud13; Pre-mRNA-splicing factor of RES complex
    cl28087
    Location:433 → 666
    FtsK; DNA segregation ATPase FtsK/SpoIIIE and related proteins [Cell cycle control, cell division, chromosome partitioning]

RNA

  1. NR_002407.1 RNA Sequence

    Status: REVIEWED

Nucleotide Protein
Heading Accession and Version
Protein Accession Links
GenPept Link UniProtKB Link
Q9GRZ3.1

Gene LinkOut

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