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Slc35b1 solute carrier family 35, member B1 [ Mus musculus (house mouse) ]

Gene ID: 110172, updated on 28-Apr-2024

Summary

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Official Symbol
Slc35b1provided by MGI
Official Full Name
solute carrier family 35, member B1provided by MGI
Primary source
MGI:MGI:1343133
See related
Ensembl:ENSMUSG00000020873 AllianceGenome:MGI:1343133
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Mus musculus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
Also known as
AXER; Ugalt2; UGTrel1
Summary
Predicted to enable UDP-galactose transmembrane transporter activity and UDP-glucose transmembrane transporter activity. Predicted to be involved in UDP-galactose transmembrane transport. Predicted to act upstream of or within carbohydrate transport. Predicted to be located in endoplasmic reticulum and membrane. Predicted to be integral component of membrane. Predicted to be integral component of Golgi membrane and integral component of endoplasmic reticulum membrane. Is expressed in genitourinary system; jaw; skeleton; and submandibular gland primordium. Orthologous to human SLC35B1 (solute carrier family 35 member B1). [provided by Alliance of Genome Resources, Apr 2022]
Expression
Ubiquitous expression in large intestine adult (RPKM 76.5), duodenum adult (RPKM 41.3) and 28 other tissues See more
Orthologs
human all
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Genomic context

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Location:
11 D; 11 59.01 cM
Exon count:
9
Annotation release Status Assembly Chr Location
RS_2024_02 current GRCm39 (GCF_000001635.27) 11 NC_000077.7 (95275696..95282602)
108.20200622 previous assembly GRCm38.p6 (GCF_000001635.26) 11 NC_000077.6 (95384856..95391776)

Chromosome 11 - NC_000077.7Genomic Context describing neighboring genes Neighboring gene STARR-positive B cell enhancer ABC_E1841 Neighboring gene predicted gene 11520 Neighboring gene STARR-seq mESC enhancer starr_30502 Neighboring gene STARR-positive B cell enhancer ABC_E594 Neighboring gene family with sequence similarity 117, member A Neighboring gene STARR-positive B cell enhancer ABC_E3009 Neighboring gene CapStarr-seq enhancer MGSCv37_chr11:95253828-95254029 Neighboring gene STARR-seq mESC enhancer starr_30505 Neighboring gene STARR-positive B cell enhancer ABC_E3010 Neighboring gene STARR-positive B cell enhancer ABC_E10708 Neighboring gene speckle-type BTB/POZ protein Neighboring gene predicted gene, 53646

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Expression

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  • Project title: Mouse ENCODE transcriptome data
  • Description: RNA profiling data sets generated by the Mouse ENCODE project.
  • BioProject: PRJNA66167
  • Publication: PMID 25409824
  • Analysis date: n/a

Bibliography

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Related articles in PubMed

  1. Molecular cloning and characterization of a novel isoform of the human UDP-galactose transporter, and of related complementary DNAs belonging to the nucleotide-sugar transporter gene family. Ishida N, et al. J Biochem, 1996 Dec. PMID 9010752
  2. The I.M.A.G.E. Consortium: an integrated molecular analysis of genomes and their expression. Lennon G, et al. Genomics, 1996 Apr 1. PMID 8617505
  3. Subtractive hybridisation screen identifies sexually dimorphic gene expression in the embryonic mouse gonad. McClive PJ, et al. Genesis, 2003 Oct. PMID 14595844
  4. A Novel GLP1 Receptor Interacting Protein ATP6ap2 Regulates Insulin Secretion in Pancreatic Beta Cells. Dai FF, et al. J Biol Chem, 2015 Oct 9. PMID 26272612, Free PMC Article
  5. Comparative mapping of distal murine chromosome 11 and human 17q21.3 in a region containing a modifying locus for murine plasma von Willebrand factor level. Mohlke KL, et al. Genomics, 1998 Nov 15. PMID 9806826

See all (24) citations in PubMed

GeneRIFs: Gene References Into Functions

Variation

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Alleles

Alleles of this type are documented at Mouse Genome Informatics  (MGI)
  • Gene trapped (1) 
  • Targeted (1) 
  • Endonuclease-mediated (2) 

Interactions

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Products Interactant Other Gene Complex Source Pubs Description

General gene information

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Markers

Homology

Gene Ontology Provided by MGI

Function Evidence Code Pubs
enables ATP:ADP antiporter activity ISO
Inferred from Sequence Orthology
more info
  
enables UDP-galactose transmembrane transporter activity IBA
Inferred from Biological aspect of Ancestor
more info
  
enables UDP-glucose transmembrane transporter activity IBA
Inferred from Biological aspect of Ancestor
more info
  
enables antiporter activity IEA
Inferred from Electronic Annotation
more info
  
Process Evidence Code Pubs
involved_in UDP-galactose transmembrane transport IBA
Inferred from Biological aspect of Ancestor
more info
  
involved_in transmembrane transport IEA
Inferred from Electronic Annotation
more info
  
Component Evidence Code Pubs
is_active_in Golgi membrane IBA
Inferred from Biological aspect of Ancestor
more info
  
located_in endoplasmic reticulum IEA
Inferred from Electronic Annotation
more info
  
is_active_in endoplasmic reticulum membrane IBA
Inferred from Biological aspect of Ancestor
more info
  
located_in endoplasmic reticulum membrane ISO
Inferred from Sequence Orthology
more info
  
located_in membrane IEA
Inferred from Electronic Annotation
more info
  

General protein information

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Preferred Names
solute carrier family 35 member B1
Names
ATP/ADP exchanger ER
UDP-galactose translocator 2
UDP-galactose transporter-related protein 1
endoplasmic reticulum ATP/ADP translocase

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001357797.2 → NP_001344726.1  solute carrier family 35 member B1 isoform 2

    Status: VALIDATED

    Source sequence(s)
    AL662875
    Conserved Domains (1) summary
    pfam08449
    Location:1 → 212
    UAA; UAA transporter family

  2. NM_016752.4 → NP_058032.3  solute carrier family 35 member B1 isoform 1

    Status: VALIDATED

    Source sequence(s)
    AL662875
    Consensus CDS
    CCDS25277.1
    UniProtKB/Swiss-Prot
    P97858, Q8CF70
    Related
    ENSMUSP00000021243.10, ENSMUST00000021243.16
    Conserved Domains (1) summary
    pfam08449
    Location:16 → 309
    UAA; UAA transporter family

RefSeqs of Annotated Genomes: GCF_000001635.27-RS_2024_02

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCm39 C57BL/6J

Genomic

  1. NC_000077.7 Reference GRCm39 C57BL/6J

    Range
    95275696..95282602
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_006531986.3 → XP_006532049.1  solute carrier family 35 member B1 isoform X1

    Conserved Domains (1) summary
    pfam08449
    Location:1 → 185
    UAA; UAA transporter family

  2. XM_030245471.1 → XP_030101331.1  solute carrier family 35 member B1 isoform X1

    Conserved Domains (1) summary
    pfam08449
    Location:1 → 185
    UAA; UAA transporter family
Nucleotide Protein Strain
Heading Accession and Version
Protein Accession Links
GenPept Link UniProtKB Link
P97858.1 GenPept UniProtKB/Swiss-Prot:P97858

Gene LinkOut

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