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Adamts5 ADAM metallopeptidase with thrombospondin type 1 motif 5 [ Cricetulus griseus (Chinese hamster) ]

Gene ID: 100761876, updated on 8-Mar-2024

Summary

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Gene symbol
Adamts5
Gene description
ADAM metallopeptidase with thrombospondin type 1 motif 5
Locus tag
I79_018002
See related
Ensembl:ENSCGRG00015000680
Gene type
protein coding
RefSeq status
MODEL
Organism
Cricetulus griseus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Cricetidae; Cricetinae; Cricetulus
Orthologs
human mouse all
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Genomic context

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Location:
chromosome: 4
Exon count:
8
Annotation release Status Assembly Chr Location
104 current CriGri_1.0 (GCF_000223135.1) Unplaced Scaffold NW_003614768.1 (240582..277258, complement)
104 current CriGri-PICRH-1.0 (GCF_003668045.3) 4 NC_048597.1 (11158298..11195034)

NW_003614768.1Genomic Context describing neighboring genes Neighboring gene ADAM metallopeptidase with thrombospondin type 1 motif 1 Neighboring gene small nucleolar RNA SNORA68 Neighboring gene 40S ribosomal protein S25-like

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Bibliography

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GeneRIFs: Gene References Into Functions

General gene information

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Markers

Homology

Gene Ontology Provided by RefSeq

Function Evidence Code Pubs
enables metalloendopeptidase activity IEA
Inferred from Electronic Annotation
more info
 PubMed 
enables zinc ion binding IEA
Inferred from Electronic Annotation
more info
 PubMed 
Process Evidence Code Pubs
involved_in extracellular matrix organization IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in proteolysis IEA
Inferred from Electronic Annotation
more info
 PubMed 
Component Evidence Code Pubs
located_in collagen-containing extracellular matrix IEA
Inferred from Electronic Annotation
more info
 PubMed 

General protein information

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Preferred Names
A disintegrin and metalloproteinase with thrombospondin motifs 5
Names
a disintegrin-like and metallopeptidase (reprolysin type) with thrombospondin type 1 motif, 5 (aggrecanase-2)

NCBI Reference Sequences (RefSeq)

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RefSeqs of Annotated Genomes: Cricetulus griseus Annotation Release 104 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference CriGri_1.0 Primary Assembly

Genomic

  1. NW_003614768.1 Reference CriGri_1.0 Primary Assembly

    Range
    240582..277258 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_003509793.4 → XP_003509841.1  A disintegrin and metalloproteinase with thrombospondin motifs 5

    UniProtKB/TrEMBL
    A0A8C2LCH6, G3I3J4
    Conserved Domains (6) summary
    smart00209
    Location:569 → 621
    TSP1; Thrombospondin type 1 repeats
    cd04273
    Location:268 → 472
    ZnMc_ADAMTS_like; Zinc-dependent metalloprotease, ADAMTS_like subgroup. ADAMs (A Disintegrin And Metalloprotease) are glycoproteins, which play roles in cell signaling, cell fusion, and cell-cell interactions. This particular subfamily represents domain architectures that ...
    pfam01421
    Location:268 → 475
    Reprolysin; Reprolysin (M12B) family zinc metalloprotease
    pfam01562
    Location:65 → 176
    Pep_M12B_propep; Reprolysin family propeptide
    pfam05986
    Location:731 → 851
    ADAM_spacer1; ADAM-TS Spacer 1
    cl15456
    Location:485 → 555
    ADAM_CR; ADAM cysteine-rich

Alternate CriGri-PICRH-1.0

Genomic

  1. NC_048597.1 Alternate CriGri-PICRH-1.0

    Range
    11158298..11195034
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_027412358.2 → XP_027268159.1  A disintegrin and metalloproteinase with thrombospondin motifs 5

    UniProtKB/TrEMBL
    A0A9J7FYG0, G3I3J4
    Related
    ENSCGRP00015000716.1, ENSCGRT00015000936.2
Nucleotide Protein Strain
Heading Accession and Version

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