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APEX2 apurinic/apyrimidinic endodeoxyribonuclease 2 [ Sus scrofa (pig) ]

Gene ID: 100519003, updated on 8-Mar-2024

Summary

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Official Symbol
APEX2provided by VGNC
Official Full Name
apurinic/apyrimidinic endodeoxyribonuclease 2provided by VGNC
Primary source
VGNC:VGNC:103897
See related
Ensembl:ENSSSCG00000012348
Gene type
protein coding
RefSeq status
MODEL
Organism
Sus scrofa
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Laurasiatheria; Artiodactyla; Suina; Suidae; Sus
Expression
Ubiquitous expression in ovary (RPKM 17.5), liver (RPKM 6.3) and 8 other tissues See more
Orthologs
human mouse all
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Genomic context

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Location:
chromosome: X
Exon count:
6
Annotation release Status Assembly Chr Location
106 current Sscrofa11.1 (GCF_000003025.6) X NC_010461.5 (47862682..47870579)
105 previous assembly Sscrofa10.2 (GCF_000003025.5) X NC_010461.4 (53798823..53806723)

Chromosome X - NC_010461.5Genomic Context describing neighboring genes Neighboring gene uncharacterized LOC106506966 Neighboring gene inter-alpha-trypsin inhibitor heavy chain family member 6 Neighboring gene 6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 1 Neighboring gene trophinin Neighboring gene 5'-aminolevulinate synthase 2 Neighboring gene PAGE family member 2B

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Expression

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  • Project title: Transcriptome data used for gene annotation
  • Description: Nine kinds of tissues and a mixture of multiple tissues were sequenced for genome annotation
  • BioProject: PRJNA311523
  • Publication: PMID 27646534
  • Analysis date: Thu Dec 14 17:10:49 2017

Bibliography

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GeneRIFs: Gene References Into Functions

General gene information

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Markers

Homology

Gene Ontology Provided by RefSeq

Function Evidence Code Pubs
enables DNA binding IEA
Inferred from Electronic Annotation
more info
 PubMed 
enables DNA-(apurinic or apyrimidinic site) endonuclease activity IEA
Inferred from Electronic Annotation
more info
 PubMed 
enables double-stranded DNA 3'-5' DNA exonuclease activity IEA
Inferred from Electronic Annotation
more info
 PubMed 
enables endonuclease activity IEA
Inferred from Electronic Annotation
more info
 PubMed 
enables phosphoric diester hydrolase activity IEA
Inferred from Electronic Annotation
more info
 PubMed 
enables zinc ion binding IEA
Inferred from Electronic Annotation
more info
 PubMed 
Process Evidence Code Pubs
involved_in base-excision repair IEA
Inferred from Electronic Annotation
more info
 PubMed 
Component Evidence Code Pubs
located_in nucleus IEA
Inferred from Electronic Annotation
more info
 PubMed 

General protein information

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Preferred Names
DNA-(apurinic or apyrimidinic site) lyase 2

NCBI Reference Sequences (RefSeq)

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RefSeqs of Annotated Genomes: Sus scrofa Annotation Release 106 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference Sscrofa11.1 Primary Assembly

Genomic

  1. NC_010461.5 Reference Sscrofa11.1 Primary Assembly

    Range
    47862682..47870579
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_003135109.4 → XP_003135157.1  DNA-(apurinic or apyrimidinic site) lyase 2

    UniProtKB/TrEMBL
    A0A4X1VET7, A0A8D0K6F6, A0A8D1XFU6, K7GNL1
    Related
    ENSSSCP00000029465.3, ENSSSCT00000035798.4
    Conserved Domains (2) summary
    cd09088
    Location:3 → 311
    Ape2-like_AP-endo; Human Ape2-like subfamily of the ExoIII family purinic/apyrimidinic (AP) endonucleases
    pfam06839
    Location:462 → 511
    zf-GRF; GRF zinc finger
Nucleotide Protein
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