AFF2 ALF transcription elongation factor 2 [Pongo abelii (Sumatran orangutan)] - Gene

Summary

Gene symbol: AFF2
Gene description: ALF transcription elongation factor 2
Locus tag: CR201_G0041806
See related: Ensembl:ENSPPYG00000020800
Gene type: protein coding
RefSeq status: MODEL
Organism: Pongo abelii
Lineage: Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Pongo
Orthologs: human mouse all
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Genomic context

Location:: chromosome: X

Exon count:: 22

Annotation release	Status	Assembly	Chr	Location
RS_2024_02	current	NHGRI_mPonAbe1-v2.0_pri (GCF_028885655.2)	X	NC_072008.2 (154846027..155344070)
RS_2023_04	previous assembly	NHGRI_mPonAbe1-v1.1-hic.freeze_pri (GCF_028885655.1)	X	NC_072008.1 (154846039..155340926)

Chromosome X - NC_072008.2 Genomic Context describing neighboring genes

Genomic regions, transcripts, and products

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Genomic Sequence:

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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GeneRIFs: Gene References Into Functions

What's a GeneRIF?

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General gene information

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Markers

Xq4086 (e-PCR)
- UniSTS:242955

RH18451 (e-PCR)
- UniSTS:76815

SHGC-7435 (e-PCR)
- UniSTS:1300

DXS7394 (e-PCR)
- UniSTS:78356

AFF2 (e-PCR)
- UniSTS:506659

DXS8091 (e-PCR), detects polymorphism
- UniSTS:24372

RH120439 (e-PCR)
- UniSTS:133434

DXS1691 (e-PCR)
- UniSTS:148816

RH70649 (e-PCR)
- UniSTS:23918

DXS8273 (e-PCR)
- UniSTS:38281

DXS1318 (e-PCR)
- UniSTS:99211

DXS7812 (e-PCR)
- UniSTS:99216

NoName (e-PCR)
- UniSTS:99231

RH45213 (e-PCR)
- UniSTS:91829

RH119837 (e-PCR)
- UniSTS:133582

AFM323YF1 (e-PCR)
- UniSTS:14299

DXS6729 (e-PCR)
- UniSTS:60642

Homology

NCBI Orthologs

Orthologs from OrthoDB

Gene Ontology Provided by RefSeq

Function	Evidence Code	Pubs
enables G-quadruplex RNA binding	IEA Inferred from Electronic Annotation more info	PubMed

Process	Evidence Code	Pubs
involved_in regulation of RNA splicing	IEA Inferred from Electronic Annotation more info	PubMed

Component	Evidence Code	Pubs
located_in nuclear speck	IEA Inferred from Electronic Annotation more info	PubMed
located_in nucleus	IEA Inferred from Electronic Annotation more info	PubMed

General protein information

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Preferred Names: AF4/FMR2 family member 2

NCBI Reference Sequences (RefSeq)

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RefSeqs of Annotated Genomes: GCF_028885655.2-RS_2024_02

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference NHGRI_mPonAbe1-v2.0_pri Primary Assembly

Genomic

NC_072008.2 Reference NHGRI_mPonAbe1-v2.0_pri Primary Assembly

Range

154846027..155344070

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GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

XM_009235348.4 → XP_009233623.1 AF4/FMR2 family member 2 isoform X3

UniProtKB/TrEMBL

A0A2J8XTU6, A0A2J8XTV0, H2PX09

Conserved Domains (1) summary

pfam05110
Location:19 → 1273

AF-4; AF-4 proto-oncoprotein
XM_002832215.4 → XP_002832261.1 AF4/FMR2 family member 2 isoform X2

UniProtKB/TrEMBL

A0A2J8XTS3, A0A8I5YQP1

Conserved Domains (1) summary

pfam05110
Location:19 → 1298

AF-4; AF-4 proto-oncoprotein
XM_002832217.4 → XP_002832263.1 AF4/FMR2 family member 2 isoform X4

UniProtKB/TrEMBL

A0A2J8XTU6, H2PX09

Conserved Domains (1) summary

pfam05110
Location:19 → 1269

AF-4; AF-4 proto-oncoprotein
XM_054545161.2 → XP_054401136.1 AF4/FMR2 family member 2 isoform X1
XM_054545162.2 → XP_054401137.1 AF4/FMR2 family member 2 isoform X5
XM_054545163.2 → XP_054401138.1 AF4/FMR2 family member 2 isoform X6