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Items: 4

1.

Heterogeneous in vitro effects of doxorubicin on gene expression in primary human liposarcoma cultures

(Submitter supplied) Doxorubicin is considered one of the most potent established chemotherapeutics in the treatment of liposarcoma; however, the response rates usually below 30%, are still disappointing. This study was performed to identify gene expression changes in liposarcoma after doxorubicin treatment. Cells of 19 primary human liposarcoma were harvested intraoperatively and brought into cell culture. Cells were incubated with doxorubicin for 24 h, RNA was isolated and differential gene expression was analysed by the microarray technique. more...
Organism:
Homo sapiens
Type:
Expression profiling by array
Dataset:
GDS3514
Platform:
GPL96
38 Samples
Download data: CEL, CHP
Series
Accession:
GSE12972
ID:
200012972
2.
Full record GDS3514

Liposarcoma response to doxorubicin in vitro

Analysis of various types of liposarcomas treated with doxorubicin in vitro. While doxorubicin is an established chemotherapeutic for treating liposarcomas, the response to this drug is low. Results provide insight into the molecular basis of the resistance of liposarcomas to doxorubicin.
Organism:
Homo sapiens
Type:
Expression profiling by array, count, 2 agent, 3 development stage, 6 disease state, 19 specimen sets
Platform:
GPL96
Series:
GSE12972
38 Samples
Download data: CEL, CHP
3.

[HG-U133A] Affymetrix Human Genome U133A Array

(Submitter supplied) Affymetrix submissions are typically submitted to GEO using the GEOarchive method described at http://0-www-ncbi-nlm-nih-gov.brum.beds.ac.uk/projects/geo/info/geo_affy.html June 03, 2009: annotation table updated with netaffx build 28 June 08, 2012: annotation table updated with netaffx build 32 June 24, 2016: annotation table updated with netaffx build 35 Protocol: see manufacturer's web site The U133 set includes 2 arrays with a total of 44928 entries and was indexed 29-Jan-2002. more...
Organism:
Homo sapiens
364 DataSets
1125 Series
11 Related Platforms
42430 Samples
Download data
Platform
Accession:
GPL96
ID:
100000096
4.

Patient no. 7: control

Organism:
Homo sapiens
Source name:
Liposarcoma culture from tumor 385, untreated
Platform:
GPL96
Series:
GSE12972
Dataset:
GDS3514
Download data: CEL, CHP
Sample
Accession:
GSM325250
ID:
300325250
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