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Items: 1 to 20 of 48

1.

Functional and Transcriptomic Recovery of Infarcted Mouse Myocardium Treated with Bone Marrow Mononuclear Cells

(Submitter supplied) Although bone marrow-derived mononuclear cells (BMNC) have been extensively used in cell therapy for cardiac diseases, little mechanistic information is available to support reports of their efficacy. To address this shortcoming, we compared structural and functional recovery and associated global gene expression profiles in post-ischaemic myocardium treated with BMNC transplantation. BMNC suspensions were injected into cardiac scar tissue 10 days after experimental myocardial infarction. more...
Organism:
Mus musculus
Type:
Expression profiling by array
Platform:
GPL5371
12 Samples
Download data: GPR
Series
Accession:
GSE29769
ID:
200029769

PubMed Full text in PMC Similar studies Analyze with GEO2R

2.

Alterations in the Brain Transcriptome in Plasmodium Berghei ANKA Infected Mice

(Submitter supplied) We have used cDNA microarrays to compare gene expression profiles in brains from normal mice to those infected with the Anka strain of Plasmodium berghei, a model of cerebral malaria. For each of three brains in each group, we computed ratios of all quantifiable genes with a composite reference sample and then computed ratios of gene expression in infected brains with untreated controls. Of the almost 12,000 unigenes adequateluy quantified in all arrays, about 3% were significantly downregulated (p<0.05, >50% fold change) and about 7% were upregulated. more...
Organism:
Mus musculus
Type:
Expression profiling by array
Platform:
GPL5371
6 Samples
Download data
Series
Accession:
GSE24086
ID:
200024086

Analyze with GEO2R

3.

Cardiac gene expression and systemic cytokine profile are complementary in a murine model of post ischemic heart failure

(Submitter supplied) After myocardial infarction (MI) activation of the immune system and inflammatory mechanisms, among others, can lead to ventricular remodeling and heart failure (HF). Interaction between these systemic alterations and corresponding changes in the heart has not been extensively examined in the setting of chronic ischemia. The main purpose of this study was to investigate alterations in cardiac gene and systemic cytokine profile in mice with post-ischemic HF. more...
Organism:
Mus musculus
Type:
Expression profiling by array
Dataset:
GDS3655
Platform:
GPL5371
8 Samples
Download data: GPR
Series
Accession:
GSE18703
ID:
200018703

PubMed Full text in PMC Similar studies Analyze with GEO2R

4.
Full record GDS3655

Post-ischemic heart failure model

Analysis of C57BL/6 hearts 7 weeks after inducing myocardial infarction. Myocardial infarcts were produced by ligation of the descending branch of the left coronary artery. Results provide insight into the molecular pathogenesis of post-ischemic heart failure.
Organism:
Mus musculus
Type:
Expression profiling by array, log2 ratio, 2 disease state sets
Platform:
GPL5371
Series:
GSE18703
8 Samples
Download data: GPR
DataSet
Accession:
GDS3655
ID:
3655

PubMed Full text in PMC Similar studies GEO Profiles Analyze DataSet

5.

Transcriptomic alterations in Trypanosoma cruzi-infected cardiac myocytes

(Submitter supplied) Trypanosoma cruzi infection is a major cause of cardiomyopathy. Gene profiling studies of hearts from infected mice have revealed prominent changes in gene expression within many functional pathways. This variety of transcriptomic changes in infected mice raises the question of whether gene expression alterations in whole hearts are due to changes in infected cardiac myocytes or other cells or even to systemic effects of the infection on the heart. more...
Organism:
Mus musculus
Type:
Expression profiling by array
Platform:
GPL5371
8 Samples
Download data: GPR
Series
Accession:
GSE17330
ID:
200017330

PubMed Full text in PMC Similar studies Analyze with GEO2R

6.

“Compensatory” transcriptional mechanisms: Comparison of transcriptomes of Cx43 null and knockdown astrocytes

(Submitter supplied) Our previous studies on brains and hearts of Cx null mice have revealed that expression level, control and coordination of a very large number of genes are regulated compared to wildtype littermates. This result suggests the possibility that the phenotype of the Cx null animals may include genes not only linked to the intracellular communication that gap junction channels provide but also to genes with very different functions. more...
Organism:
Mus musculus
Type:
Expression profiling by array
Platform:
GPL5371
14 Samples
Download data: GPR
Series
Accession:
GSE8168
ID:
200008168

PubMed Full text in PMC Similar studies Analyze with GEO2R

7.

Gap junction and purinergic P2 receptor proteins as a functional unit: insights from transcriptomics

(Submitter supplied) Gap junctions and purinergic P2 receptors (P2Rs) can be regarded as belonging to a common functional unit, given that they are involved in the transmission of calcium signals between cells. We have previously shown that deletion of the Gja1 gene alters expression levels of numerous genes encoding proteins with diverse functions, including purinergic, P2Rs, and have found that genes synergistically or antagonistically expressed in wildtype tissues are more prone to be similarly or oppositely regulated in Cx43-nulls. more...
Organism:
Mus musculus
Type:
Expression profiling by array
Platforms:
GPL1698 GPL5371
18 Samples
Download data: GPR
Series
Accession:
GSE8105
ID:
200008105

PubMed Similar studies Analyze with GEO2R

8.

AECOM 32K MOUSE OLIGONUCLEOTIDE ARRAY, MO2 printing series

(Submitter supplied) The arrays are printed with 31,769 70mer probes Qiagen V3.0 oligo set (http://oligos.qiagen.com/arrays/oligosets_mouse.php ) plus controls. Each slide is composed of 48 blocks, arranged in 4 columns and 12 rows, each block containing 700 spots in staggered pattern in 28 columns and 25 rows. The arrays are printed under rigorous clean-room conditions and quality control is employed all along the way.
Organism:
Mus musculus
1 DataSet
6 Series
40 Samples
Download data
Platform
Accession:
GPL5371
ID:
100005371

9.

Infarcted Mouse Myocardium Treated with Bone Marrow Mononuclear Cells rep4

Organism:
Mus musculus
Source name:
Infarcted Mouse Myocardium Treated with Bone Marrow Mononuclear Cells (channel 1) Universal mouse RNA reference (channel 2)
Platform:
GPL5371
Series:
GSE29769
Download data: GPR
Sample
Accession:
GSM738116
ID:
300738116

10.

Infarcted Mouse Myocardium Treated with Bone Marrow Mononuclear Cells rep3

Organism:
Mus musculus
Source name:
Infarcted Mouse Myocardium Treated with Bone Marrow Mononuclear Cells (channel 1) Universal mouse RNA reference (channel 2)
Platform:
GPL5371
Series:
GSE29769
Download data: GPR
Sample
Accession:
GSM738115
ID:
300738115

11.

Infarcted Mouse Myocardium Treated with Bone Marrow Mononuclear Cells rep2

Organism:
Mus musculus
Source name:
Infarcted Mouse Myocardium Treated with Bone Marrow Mononuclear Cells (channel 1) Universal mouse RNA reference (channel 2)
Platform:
GPL5371
Series:
GSE29769
Download data: GPR
Sample
Accession:
GSM738114
ID:
300738114

12.

Infarcted Mouse Myocardium Treated with Bone Marrow Mononuclear Cells rep1

Organism:
Mus musculus
Source name:
Infarcted Mouse Myocardium Treated with Bone Marrow Mononuclear Cells (channel 1) Universal mouse RNA reference (channel 2)
Platform:
GPL5371
Series:
GSE29769
Download data: GPR
Sample
Accession:
GSM738113
ID:
300738113

13.

Infected_brain_rep3

Organism:
Mus musculus
Source name:
Universal mouse RNA reference (channel 1) Infected_brain (channel 2)
Platform:
GPL5371
Series:
GSE24086
Download data
Sample
Accession:
GSM593020
ID:
300593020

14.

Infected_brain_rep2

Organism:
Mus musculus
Source name:
Universal mouse RNA reference (channel 1) Infected_brain (channel 2)
Platform:
GPL5371
Series:
GSE24086
Download data
Sample
Accession:
GSM593019
ID:
300593019

15.

Infected_brain_rep1

Organism:
Mus musculus
Source name:
Universal mouse RNA reference (channel 1) Infected_brain (channel 2)
Platform:
GPL5371
Series:
GSE24086
Download data
Sample
Accession:
GSM593018
ID:
300593018

16.

Control_brain_rep3

Organism:
Mus musculus
Source name:
Universal mouse RNA reference (channel 1) Control_brain (channel 2)
Platform:
GPL5371
Series:
GSE24086
Download data
Sample
Accession:
GSM593017
ID:
300593017

17.

Control_brain_rep2

Organism:
Mus musculus
Source name:
Universal mouse RNA reference (channel 1) Control_brain (channel 2)
Platform:
GPL5371
Series:
GSE24086
Download data
Sample
Accession:
GSM593016
ID:
300593016

18.

Control_brain_rep1

Organism:
Mus musculus
Source name:
Universal mouse RNA reference (channel 1) Control_brain (channel 2)
Platform:
GPL5371
Series:
GSE24086
Download data
Sample
Accession:
GSM593015
ID:
300593015

19.

Adult_mouse_heart_infarcted_rep4

Organism:
Mus musculus
Source name:
Adult_mouse_heart_infarcted (channel 1) Universal mouse RNA reference (channel 2)
Platform:
GPL5371
Series:
GSE18703 GSE29769
Dataset:
GDS3655
Download data: GPR
Sample
Accession:
GSM464409
ID:
300464409

20.

Adult_mouse_heart_infarcted_rep3

Organism:
Mus musculus
Source name:
Adult_mouse_heart_infarcted (channel 1) Universal mouse RNA reference (channel 2)
Platform:
GPL5371
Series:
GSE18703 GSE29769
Dataset:
GDS3655
Download data: GPR
Sample
Accession:
GSM464408
ID:
300464408

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