3RW6


Conserved Protein Domain Family
Tap-RNA_bind
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pfam09162: Tap-RNA_bind 
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Tap, RNA-binding
Members of this family adopt a structure consisting of an alpha+beta sandwich with an antiparallel beta-sheet, arranged in a 2(beta-alpha-beta) motif. They are mainly found in mRNA export factors, and mediate the sequence nonspecific nuclear export of cellular mRNAs as well as the sequence-specific export of retroviral mRNAs bearing the constitutive transport element.
Links
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Statistics
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PSSM-Id: 462696
Aligned: 54 rows
Threshold Bit Score: 86.0682
Created: 23-Mar-2022
Updated: 17-Oct-2022
Structure
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Program:
Drawing:
Aligned Rows:
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PubMed ReferencesClick to see Conserved Features Help
Sequence Alignment
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Format: Row Display: Color Bits: Type Selection: 
3RW6_A         24 WFKITIPYGRKYDKAWLLSMIQSKCS-VPFTPIEFHYENTRAQFFVEDASTASALKAVNYKI-LDRENRRISIIINSS-A 100 
XP_009021889  120 WYKITIPHAKDLDKDFIIKSINGLLK-TPMMPWNFSYENKMATFNIKGTEEARAVKGVSKRI-TTPNGFKMIILVGPCaM 197 
PDM71324      704 W-RVKIPSGQKYGAPFILSTLSAHVE--NLKPIMPKMFSTEFVFFVRDDDAAHAIRSVHRRIkHAETGDRLNIITNLV-N 779 
EKC41871       86 WYKVIIPYGKKGGKDFILKSLTERVN-IPFKPVDFHFEQEKAVFFVQEKQEANAIRSQDKKI-QLPNGFKMIVLVKPS-P 162 
Q17MK6        130 WYEVKIPYGHKYEKEFILRSLVNAISpLIFIPQYWKVEDTAVSFYIEDFQAAEALQKIDRTI-GLPDGRKMIVIVRNS-N 207  yellow fever ...
Q7QK79          8 WYEVRIPYGNKYEKEFILRSIQQAITpQMFIPLYYKANESGAVFFVEDFQAADAIMRANRSI-QTPDGRRMILVVRNN-P 85   Anopheles gam...
ETN60147      140 WYEVRIPYGQKYEKEFVLRSIQQAISpQIFIPRYYKAAESCATFYVEDFATAEAIQKMDRKI-DTPDGRKMILLVRSN-H 217 
1_pfamImport    1 WYKVTIRYGGRYEKDYLLKLLGNYIKpLPFIPIGYKVTSNDATFTIEDHNAAEELLNADKRI-TVNDGFKINLQVRSF-N 78  
XP_012060862  131 WYRVTIPYGQKYEKDFIINTLLNYITpDVFVPILYKTSTTDASFYIDDYKTAVALQSCDYKI-TMSDGFKLQVKVKPG-F 208 
EFX66242      114 WSKVTIPHGKKFEKDFILKTLLNASK-VSFIPIYYHIEGNNAVFFIEDSTAAEALSTLNKQI-TLHDGFKLIILVKWSpA 191 

3RW6_A        101 PPH 103 
XP_009021889  198 PPT 200 
PDM71324      780 APW 782 
EKC41871      163 PPV 165 
Q17MK6        208 PQY 210  yellow fever mosquito
Q7QK79         86 PPT 88   Anopheles gambiae str. PEST
ETN60147      218 PVF 220 
1_pfamImport   79 PLV 81  
XP_012060862  209 PVY 211 
EFX66242      192 PNL 194
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