Conserved Protein Domain Family
Bap31_Bap29_C
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pfam18035: Bap31_Bap29_C (this model, PSSM-Id:407872 is obsolete and has been replaced by 465623)
Bap31/Bap29 cytoplasmic coiled-coil domain
Bap31 is a polytopic integral protein of the endoplasmic reticulum membrane and a substrate of caspase-8. Bap31 is cleaved within its cytosolic domain, generating pro-apoptotic p20 Bap31. This entry represents the cytoplasmic domain which forms a heterodimeric coiled-coil with Bap29. This Bap29 and Bap31 are homologous to each other and this entry includes both proteins.
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Statistics
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PSSM-Id: 407872
Aligned: 51 rows
Threshold Bit Score: 46.8849
Created: 21-May-2020
Updated: 7-Aug-2020
Structure
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Aligned Rows:
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Sequence Alignment
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Format: Row Display: Color Bits: Type Selection: 
EFX80917     171 EKISNLQK---ELA----EAKkersqavKDLEAFKSQSEGVAREYDRLAEEHSKLVkklavleGEGGSDKKDD 236 common water flea
XP_004345792 156 KENETLTQ---KLK----ESEeakrkalVNVDNLVEQAKRNQAALDRHFEERQQEAq-----sSAPAERKKDK 216 Capsaspora owczarzaki ...
EPB84621     161 DKIKSLQSevvQLQ----SKK-------SEYENLKQKIDQEAADYHKLADERTKL------------NPTSTI 210 Mucor circinelloides f...
XP_015788247 189 SELAGIKE---ELI----KSKne----lAKAEAVKKQAEGISREYDRLAEEHEKLIk-----kMGMAGDKKGD 245 two-spotted spider mite
XP_002403043 181 RDVRELKK---ELE----AAKkdaehltTDRDALKVQAENLSKEYDRLCEEHAKAQkt---laAGEPSTKKDN 243 black-legged tick
XP_008206250 175 AKLKELES---ELE----KEK-------KDKAAVKSQAESLAKEYDRLNEEHSKL--------LSAGGDKKSD 225 jewel wasp
XP_006558287 173 NQIKELQTknkELEdqviKEK-------KDKETIKSQAESLAKEYDRLNDEHSKC--------LQSSGDKKSD 230 honey bee
XP_011143389 177 NQIKELQAknlELEndliKER-------KDKEAMKSQADSLAKEYDRLNNEHAKI--------AQSSGDKKSD 234 Jerdon's jumping ant
NP_001155477 160 EALTELRK---ELE----LIK-------ADRDAIKSQAESVSKEYDRLMTEHEKLQk-----tV-GNESKKDD 212 pea aphid
XP_019855950 175 TRITELEK---EVKkv-----------lADRDAMRKQAESLHAEYDRLSGEYQKIQk-----eQDGEEDKKEQ 228 Amphimedon queenslandica
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