Conserved Protein Domain Family
RPAP3_C
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pfam13877: RPAP3_C (this model, PSSM-Id:372776 is obsolete and has been replaced by 464012)
Potential Monad-binding region of RPAP3
This domain is found at the C-terminus of RNA-polymerase II-associated proteins. These proteins bind to Monad and are involved in regulating apoptosis. They contain TPR-repeats towards the N_terminus.
Links
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Statistics
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PSSM-Id: 372776
Aligned: 152 rows
Threshold Bit Score: 35.279
Created: 1-May-2019
Updated: 18-Jul-2019
Structure
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Aligned Rows:
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PubMed ReferencesClick to see Conserved Features Help
Sequence Alignment
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Format: Row Display: Color Bits: Type Selection: 
jgi:MICPUN_57378               107 APSSAAEFEKTWRRScKSTDARWRyl-------gLVAGTREGRIAKLFR-VEINGTVLSELVAALAAGYAGDGrsIRddd 178  Micromonas commoda...
WGS:AAGF:cds.TTHERM_00326680A  694 QEINSTKFMNEWNHIkSDKHTSFK----------YLMQVDSSQLVNAFK-EGLELHTLKEIFETLNSQYSLNDnkT---- 758  Tetrahymena thermophila SB210...
Q5A857                         213 VMLSPMHFLTTLKQLpEEQKLNGYk---------YILNIDNQSYADIFS-SGIDTEFLQFYLDAASYVSTNDSlpNWn-- 280  Candida albicans...
EER36257                       207 NEKSPMHFLTALKQLpDNKKSNGYk---------YVLNLDSDSYQTIFE-SGIDTEFLSFFLDAVNYASTQNDipNWn-- 274  Candida tropicalis MYA-3404...
EGW34544                       198 QEISPMHYLTTLKFLpEDQKAKGYk---------FVLGLDSDSYENIFGsSGIETEFLQFFLDAAVYFSTHENefPDl-- 266  Spathaspora passalidarum NRRL Y-27907...
Q6CDD4                         214 ACLNAYTLAQLLKSPqNQMKEVRT----------YLYNYDVAQWPHIFGrGGIDADFIEEMLKAIIENEDNSQr------ 277  Yarrowia lipolytica...
XP_018652524                   380 PPSNWFQLERELRELcQRNSSSNYrpnlskeaviYLCNIQPVDYVKLFG-ENMDSDFLLRMLQAFYLSDQLTNq------ 452  Schistosoma mansoni...
GAA36502                       354 gPSNWFQLERELRELcGRARDALPkaa-----veYLCRIDPTQYENVIG-SNLETSFLTQMLLALTENNVLPPa------ 421  Clonorchis sinensis...
CDS32354                       297 PPTNWFQLERDLRELiPYGDSLTPqa------vdYLCSLEPQNYKSVIG-GSLTSSCLGRLVRAMVVSSSLSSt------ 363  Hymenolepis microstoma...
XP_018653141                   660 pITNSYEFQNYWINIqHLKRLNYInamn--eiiiLLHNILPEQLPKLIG-IRMEAEMLDDLLNAINVSMNTENnnSL--- 733  Schistosoma mansoni...

jgi:MICPUN_57378               179 ewagargaraigERVRAFLAELATCGRFALAAKLMGSG 216  Micromonas commoda
WGS:AAGF:cds.TTHERM_00326680A  759 --------------IKDYITQIPNLKRFKLSIGLFTAN 782  Tetrahymena thermophila SB210
Q5A857                         281 ------------QVVLNHLKQFSTFKRFDLSLLMCDDK 306  Candida albicans
EER36257                       275 ------------TLILNHFKQFSTFKRYDLAMLMCDDS 300  Candida tropicalis MYA-3404
EGW34544                       267 -----------nSTVLQHLQRFAKFKKYDLAMLMCDDN 293  Spathaspora passalidarum NRRL Y-27907
Q6CDD4                         278 --------------pRDIVQSMKKCERFNIANTFVPKD 301  Yarrowia lipolytica
XP_018652524                   453 -------------hIVDRLLFLSKLPRFDIAWMMIDGL 477  Schistosoma mansoni
GAA36502                       422 -------------eIALRLDHLCRLPRFDVAWMMVDDc 446  Clonorchis sinensis
CDS32354                       364 -------------qKAERLKSLTNLPRFSVAWMLAEDS 388  Hymenolepis microstoma
XP_018653141                   734 -------------WIYDILIQLSKTARFDCALFLISDD 758  Schistosoma mansoni
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