6EZ4


Conserved Protein Domain Family
RPAP3_C
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pfam13877: RPAP3_C 
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Potential Monad-binding region of RPAP3
This domain is found at the C-terminus of RNA-polymerase II-associated proteins. These proteins bind to Monad and are involved in regulating apoptosis. They contain TPR-repeats towards the N_terminus.
Links
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Statistics
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PSSM-Id: 464012
Aligned: 124 rows
Threshold Bit Score: 39.1869
Created: 25-Mar-2022
Updated: 17-Oct-2022
Structure
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Program:
Drawing:
Aligned Rows:
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PubMed ReferencesClick to see Conserved Features Help
Sequence Alignment
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Format: Row Display: Color Bits: Type Selection: 
6EZ4_A                          16 PANSFQLE-----SDFRQLKS---SPDMLYq---YLKQIEPSLYPKLFQKN-LDPDVFNQIVK----ILhdfYIEKEKPL 79  
CDS43139                        11 FNKIDDFI-----RCWGDLEGhqsERALAD----LLMEQSRELLQEVFASS-AGLPILPRVLK----CL---LTASSEDP 73  
XP_002122252                   955 P---YEFG-----NAWNAVQPkhaVSTYKM----ILDRVPVKNIPELVTNK-TTDHMIVTFAKiaryHL---IAGVKEEV 1018
A0CMR4                         114 CKNFRDFR-----TLFSKYYIkplTQENYAelmnILQMQSEDNIKKIFSID-FHVEYFFKILEvfdySIs--TLKDGKEL 185  Paramecium tetraurelia...
WGS:AAGF:cds.TTHERM_00346790A  128 ANSFRDFK-----KNFDSQYKfpiDDVAAQniylIFKSQKEENFKKIFSLD-FDVSYFIKIIKvmkyVIqesLVPNQNAL 201 
Q6CDD4                         215 CLNAYTLA-----QLLKSPQNqmkEVRT------YLYNYDVAQWPHIFGRGgIDADFIEEMLKa--------IIENEDNS 275  Yarrowia lipolytica...
Q5A857                         214 MLSPMHFL-----TTLKQLPEeqkLNGYK-----YILNIDNQSYADIFSSG-IDTEFLQFYLDaas----yvSTNDSLPN 278  Candida albicans...
EGW34544                       199 EISPMHYL-----TTLKFLPEdqkAKGYK-----FVLGLDSDSYENIFGSSgIETEFLQFFLDaav---yfsTHENEFPD 265 
EER36257                       208 EKSPMHFL-----TALKQLPDnkkSNGYK-----YVLNLDSDSYQTIFESG-IDTEFLSFFLDavn----yaSTQNDIPN 272 
XP_011603628                   169 NRAQAEIKlqhwpKALKDCQS-------------VLE-LEAGNIKGLLRRAtV--------------------------- 207 

6EZ4_A                          80 --LI-FEILQRLSELKRFDMAV-MFMSETEK 106 
CDS43139                        74 --QRvINTLQAISSSENFELVA-LFLSDEEK 101 
XP_002122252                  1019 --DRaYGILSSLSLAQRFNMAA-MFLSKPDK 1046
A0CMR4                         186 --SFiVGFLDELVKIKDFMQQIkKFLKKSEK 214  Paramecium tetraurelia
WGS:AAGF:cds.TTHERM_00346790A  202 elLFlMEFLDQMSKVKDFQFSVpKFLSSKEK 232 
Q6CDD4                         276 --QRpRDIVQSMKKCERFNIAN-TFVPKDLK 303  Yarrowia lipolytica
Q5A857                         279 wnQVvLNHLKQFSTFKRFDLSL-LMCDDKSK 308  Candida albicans
EGW34544                       266 lnSTvLQHLQRFAKFKKYDLAM-LMCDDNTK 295 
EER36257                       273 wnTLiLNHFKQFSTFKRYDLAM-LMCDDSVK 302 
XP_011603628                   208 -----------YYHMEKFQMAA-EDLRAVLR 226
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