3RW6


Conserved Protein Domain Family
Tap-RNA_bind
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pfam09162: Tap-RNA_bind (this model, PSSM-Id:370331 is obsolete and has been replaced by 462696)
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Tap, RNA-binding
Members of this family adopt a structure consisting of an alpha+beta sandwich with an antiparallel beta-sheet, arranged in a 2(beta-alpha-beta) motif. They are mainly found in mRNA export factors, and mediate the sequence nonspecific nuclear export of cellular mRNAs as well as the sequence-specific export of retroviral mRNAs bearing the constitutive transport element.
Links
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Statistics
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PSSM-Id: 370331
Aligned: 63 rows
Threshold Bit Score: 84.1394
Created: 3-May-2019
Updated: 18-Jul-2019
Structure
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Program:
Drawing:
Aligned Rows:
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PubMed ReferencesClick to see Conserved Features Help
Sequence Alignment
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Format: Row Display: Color Bits: Type Selection: 
3RW6_A          21 SKNWFKITIPYGRKYDKAWLLSMIQSKCS-VPFTPIEFHYENTRAQFFVEDASTASALKAVNYKI-LDRENRRISIIINS 98   human
Q17MK6         127 PTSWYEVKIPYGHKYEKEFILRSLVNAISpLIFIPQYWKVEDTAVSFYIEDFQAAEALQKIDRTI-GLPDGRKMIVIVRN 205  yellow fever...
Q7QK79           7 P--WYEVRIPYGNKYEKEFILRSIQQAITpQMFIPLYYKANESGAVFFVEDFQAADAIMRANRSI-QTPDGRRMILVVRN 83   Anopheles ga...
ETN60147       137 QTSWYEVRIPYGQKYEKEFVLRSIQQAISpQIFIPRYYKAAESCATFYVEDFATAEAIQKMDRKI-DTPDGRKMILLVRS 215  Anopheles da...
XP_012060862   128 ESSWYRVTIPYGQKYEKDFIINTLLNYITpDVFVPILYKTSTTDASFYIDDYKTAVALQSCDYKI-TMSDGFKLQVKVKP 206  Atta cephalotes
XP_397092      122 DSNWYKITIPYGHKYDKDYIINNLLSYIApETFIPFMYKVVGNEATFYVDDNKIAMALADSDRKI-TTTDGFKLQVRVSK 200  honey bee
30_pfamImport    1 PSYWYKVTIRYGGRYEKDYLLKLLGNYIKpLPFIPIGYKVTSNDATFTIEDHNAAEELLNADKRI-TVNDGFKINLQVRS 79  
EDO39114       156 DSDWHRVVVNRAKIHDKEWLIKRLQSSSE-EAFQPVEFHYMGESAVFFVEGSRAAEALKRVSHSI-TVKDGSKLIITVRP 233  starlet sea ...
PDM71324       701 EKAW-RVKIPSGQKYGAPFILSTLSAHV--ENLKPIMPKMFSTEFVFFVRDDDAAHAIRSVHRRIkHAETGDRLNIITNL 777  Pristionchus...
XP_001599027   124 DSNWYKIFIPKGQKYTKEFVICNLTSCIApHTFIPymYQVVGQDSMFYVEDHRVATQLSDCNNRI-TTSDGFKMRVQVRP 202  jewel wasp

3RW6_A          99 S-APPH 103  human
Q17MK6         206 S-NPQY 210  yellow fever mosquito
Q7QK79          84 N-PPPT 88   Anopheles gambiae str. PEST
ETN60147       216 N-HPVF 220  Anopheles darlingi
XP_012060862   207 G-FPVY 211  Atta cephalotes
XP_397092      201 AgFPQC 206  honey bee
30_pfamImport   80 F-NPLV 84  
EDO39114       234 Sqkpfk 239  starlet sea anemone
PDM71324       778 V-NAPW 782  Pristionchus pacificus
XP_001599027   203 G-LPPL 207  jewel wasp
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