2XPK


Conserved Protein Domain Family
NAGidase
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pfam07555: NAGidase (this model, PSSM-Id:284884 is obsolete and has been replaced by 429533)
beta-N-acetylglucosaminidase
This family has previously been described as a hyaluronidase. However, more recently it has been shown that this family has beta-N-acetylglucosaminidase activity.
Links
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Statistics
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PSSM-Id: 284884
Aligned: 93 rows
Threshold Bit Score: 313.339
Created: 26-Jun-2015
Updated: 5-Aug-2015
Structure
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Program:
Drawing:
Aligned Rows:
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PubMed ReferencesClick to see Conserved Features Help
Sequence Alignment
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Format: Row Display: Color Bits: Type Selection: 
2XPK_A        152 RGIVEGFYGTPWTHQDRLDQIKFYGENKLNTYIYAPKDDPYHREKWREPYPES-----------EM-----------Q-- 207  Clostridium p...
WP_021892137  178 RGIVEGFYGHPYSVENRISLFEFCKRFKMNVFVYGPKSDPYHLGNWRDDYPTS-----------LT-----------E-- 233  Bacteroides s...
WP_021930106  176 RGIVEGFYGHPYSVDNRISLFEFCKRFKMNVFIYGPKSDPYHLGNWRDNYPTS-----------LT-----------E-- 231  Tannerella sp...
WP_039928479  176 RGIVEGFYGYPYSVENRLSLLEYCKRYKMNLFVYGPKADPYHLGYWRRDYPTS-----------LT-----------Qae 233  Tannerella sp...
WP_016564311  170 RGLVEGFYGHPWSMESRLNILDHMMRYKMNYYVYGPKADPYHAGNWRVNYPETvtddqrklgqiTT-----------S-- 236  Bacteroides s...
WP_021909782  179 RGLVEGYYGYPYTVAVKKDIMKFMARYKLNTYLYGAKSDPYHSGYYLDPYPTT-----------IT-----------E-- 234  Prevotella sp...
WP_022101137  175 RGIIEGFYGKPYSSSVRKDLLRFMMRYKMNCYVYGPKSDPYHSGKWGEPYPTE-----------LTesqktsgfvcqQ-- 241  Prevotella sp...
WP_022479969  175 RGLVEGYYGYPYTVEVKKDLMRFMMRHKMNTYMYGAKSDPYHSQFWGDAYPES-----------LTpeqvkngwlsqD-- 241  Prevotella sp...
WP_025278445  158 RGAIEGFYGNPYSVDAHCSLFEFFKRFKMNVFIYAPKMDPYHLGYWTEEYPTE-----------IT-----------E-- 213  Barnesiella v...
WP_021937380  174 RGIVEGFYGHPYSTESRLNLLDYCKRYKMNMFVYGPKADPYHAGKWREDYPTT-----------ITd----------Q-- 230  Bacteroides s...

2XPK_A        208 ---------R-----------MQELINASAENKVDFVFGISP-----GIdi--------rfDgD-AGEE----DFNHLIT 249  Clostridium p...
WP_021892137  234 ---------QqrffgmitqddLKTMVQAAKACNVDFIWAAHP-----GLqq--------giS-F-SNESamapGIDALMK 289  Bacteroides s...
WP_021930106  232 ---------QqkffglitqddLRRMVEAAKNCNVNFIWAAHP-----GLqqgi----sfsnT-T-EMNK----GIDALMT 287  Tannerella sp...
WP_039928479  234 qeqgmitqdD-----------LRTIAAKAQACNVNFVWAAHPam-qdGIsf--------ssE-S-AMDP----GIEAIMN 287  Tannerella sp...
WP_016564311  237 ---------D-----------IQQLATHAAACKVDFVWAVHP-----TLgs--------yyI-S-LY------WVDDIMT 275  Bacteroides s...
WP_021909782  235 ---------QqekngwltqdmFKELTSTAHATKVSFIWAIHP-----GLn-------------T-KTDQ----DVTDVMN 282  Prevotella sp...
WP_022101137  242 ---------D-----------LKDFTSVAADTKVSVVWAIHP-----GNa------------iM-NSAT----VVDDVMK 279  Prevotella sp...
WP_022479969  242 ---------M-----------IKDITSTSHETKVNFIWAIHP-----GNnf-----------vS-NGQT----VINQIMG 280  Prevotella sp...
WP_025278445  214 ---------EqrrmgwitqddVRRMAETARACNVHFVWAAHP-----GLapggqvsmdfsnT-S-TVDA----GVELLME 273  Barnesiella v...
WP_021937380  231 ---------Erhmgl-itqddLRELASKAKACNVAFIWSIHPaleggGI------------N-FsNLDP----GVEAIME 283  Bacteroides s...

2XPK_A        250 KAESLYDMGVRSFAIYWDDIQd----kSAAKHAQVLNRFNEEFVKAKG--------D--------VK--------PLITC 301  Clostridium p...
WP_021892137  290 KFDHLYSLGVRGFGVFIDDMTyt---pSGDMQAHLANEVQVKIRERYT--------Tdnt--ddqVA--------PLFFV 348  Bacteroides s...
WP_021930106  288 KFEHLHTLGVRGFGVFIDDMSyt---pSGNMQAHLANEVQIRLRNTYN--------Ntsdt-eehVS--------PLFFV 347  Tannerella sp...
WP_039928479  288 KFDHLYGLGVRGFGVFIDDITyt---pSGNMQAYLADQVQKKLKEKYN--------T--------VSatkdemvcPLFFV 348  Tannerella sp...
WP_016564311  276 KFQQLYSLGVRHFGVSVDDMSg-----hPTNQAQLPDKVQQAIDEKWN--------TadaaeadcVG--------NVLFV 334  Bacteroides s...
WP_021909782  283 KFKLMYDLGVRQFGVFTDDAGgydnpdNFPLYTQFFTNLQNQIDATWNtpgaapadT--------VK--------PLHYV 346  Prevotella sp...
WP_022101137  280 KFGSMYDLGFRQFAIFADDVNvpgdeaTMKKTADNVGAIQHAIEDKWNiagadpadT--------VK--------ALRFT 343  Prevotella sp...
WP_022479969  281 KYEKMYDLGVRQFAVFVDDVAipnsdaDMKKNADQLTALQRAIEAKWNtpgtaandT--------VR--------PLHFV 344  Prevotella sp...
WP_025278445  274 KYHHMYDLGVRAFSVCIDDMDrn---pSAQMQAHLPDQTQKRLKEEFP--------Sqae--dekIA--------PLFYV 332  Barnesiella v...
WP_021937380  284 KFDHLHKLGIRHFGVSIDDMs-----gHPYNQSDLADKAQVKLYEKFN--------KtgvseedkVG--------PLLFV 342  Bacteroides s...

2XPK_A        302 PTEYDT--GAmvsngqPR-----A------YTRIFAETVDPSIEVMWTGPGVVtNEIPLSDAQLISGIYDRNMAVWWNYP 368  Clostridium p...
WP_021892137  349 PTAYAL--NY------GA-----S------YTLNNLKKVDSEVVIAFTGYDCF-SNIRPSAIDDMAGRVGRNPVMWWNNP 408  Bacteroides s...
WP_021930106  348 PTAYAL--NY------GA-----S------STLYDLKNVDSEVVIAFTGYDCF-SNIRPSSITDMSNRVGRNPVMWWNNP 407  Tannerella sp...
WP_039928479  349 PTAYAL--NY------GG-----S------YSLNSLKSVDSDVVIAFTGYDCF-SNIRGSSCADMAGRVGRNPVMWWNNP 408  Tannerella sp...
WP_016564311  335 PTCYAL--NY------GA-----T------YSLTPIQEISSKVEVAFTGYDCF-SNVRASSFGSMAEYIGRDPIFWWNNP 394  Bacteroides s...
WP_021909782  347 PHVYNL--TW------TSqdnrqA------YFKALSE-IPEKIVFYTTGYGVWt-VPNNNDLNTMKNEFGRDVAWWWNYP 410  Prevotella sp...
WP_022101137  344 PQIYCR--AF------AG-----Pdsq-fnSFFQAMSSLPANVTVYYTGGGVW-SVPNNNDLNTLQTQFGRQAIWWWNYP 408  Prevotella sp...
WP_022479969  345 PQIYCR--SF------AG-----SqdqhdrFFRALAKT-PKYITIYTTGNGVW-SVPNDGDFNTPATPLEREVAWWWNYP 409  Prevotella sp...
WP_025278445  333 PATYALmySG------AS-----S------YLSQ-MATVDKDVVIGFTGYAVC-GDLDKKDCDAMAGYIGRNPLFWWNAT 393  Barnesiella v...
WP_021937380  343 PTQYAL--NY-------G-----T------STLSSFKNIHKDVLVAFTGYDCF-SNIRGSACDRMADLIGRNPIMWWNNP 401  Bacteroides s...

2XPK_A        369 VTDY--FKGKLAL-------------G---------PM----H------------GL-----DKGLNQyVD---FFTVNP 400  Clostridium p...
WP_021892137  409 VNDD--HDDRIYM-------------R---------EL----T------------THwt-ieKPGAINtLN---GLILNP 444  Bacteroides s...
WP_021930106  408 VNDD--HDDRIYM-------------R---------KM----T------------THwtiedPQGPINsLH---GLVMNP 444  Tannerella sp...
WP_039928479  409 VNDD--HDERIYM-------------R---------GVtahwT------------IE-----DSEPIPsLR---GLMLNP 444  Tannerella sp...
WP_016564311  395 VNDD--HDTWLYM-------------H---------GL----T------------ARwt-ieQTGAVDhMR---GFLLNP 430  Bacteroides s...
WP_021909782  411 CNDNgrSDSQIFP-------------S---------DM----YsnfidmtqvndnSR-----MPTSLEhCA---GVLSNP 456  Prevotella sp...
WP_022101137  409 CNDNgtGPSEIYPldmksnfvdmpnvG---------GG----S------------I------ASELTAsNQ---GILCNP 454  Prevotella sp...
WP_022479969  410 CNDN--ADGQIYP-------------SdmyynffemPA----V------------GN-----NSTLPNnLSrgqGIVSNP 453  Prevotella sp...
WP_025278445  394 VNDN--NDDRLYMre----------lT---------AH----Y------------ALv---pETGGIStLG---GVILNP 430  Barnesiella v...
WP_021937380  402 VNDD--YDEFLYMhgltar-wiiedkT---------PI----S------------S-------------LQ---GLVLNP 437  Bacteroides s...

2XPK_A        401 MEHAELSKISIHTAADYSWNMDNYDYDKAWNRAIDML--Yg----D--LAEDMKVF 448  Clostridium perfringens
WP_021892137  445 MNQAQASKIALFGAADYSWNPNAFDVHKNWEEVFHRI--AdpgdtQ--TAEAIKCF 496  Bacteroides sp. CAG:20
WP_021930106  445 MNQAQASKIALFGGADYGWNPSAFDVEQNWEDVFERL--Apn-dsQ--TATALKCF 495  Tannerella sp. CAG:118
WP_039928479  445 MGQAQASKVALFGGADYAWNPARFEKVSNWEASIRSLvkDd---eE--LRNAMRTF 495  Tannerella sp. 6_1_58FAA_CT1
WP_016564311  431 MNQGQVSKICNFSAADYSWNPDAYNEQSSWEQALKSI--Vkt--dE--NVKALKDF 480  Bacteroides sp. CAG:927
WP_021909782  457 MQQGEISKIALFSVADYAWNNDGFDNMKSWEAAIPAI--Is---eD--YAPAFRTL 505  Prevotella sp. CAG:755
WP_022101137  455 MEQGNASKTAIFSAGDYCWNNKGFDNMKSWEASFKGV--Lp---gNesAQKAYRFL 505  Prevotella sp. CAG:5226
WP_022479969  454 MQQGEVSKTPLFSVADYAWNHSGFNNKTSWEASFAAV--Lpg-neE--AQKAYKFL 504  Prevotella sp. CAG:891
WP_025278445  431 EKQAQAAKVGLFGLADYCWNPDRFDVSQNWYDCFDYL--AeagdtE--TAEQIRLF 482  Barnesiella viscericola
WP_021937380  438 MNQGQVSKIALFSSADYAWNPAKFDESASWEASLSSI--Vae--pE--LTEALKTF 487  Bacteroides sp. CAG:189
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