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2XPK:
Cell-penetrant, nanomolar O-GlcNAcase inhibitors selective against lysosomal hexosaminidases
PDB ID:
2XPK
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MMDB ID:
89148
PDB Deposition Date:
2010/8/26
Updated in MMDB:
2023/12
Experimental Method:
x-ray diffraction
Resolution:
2.4 Å
Source Organism:
Clostridium perfringens
Similar Structures:
VAST+
Download sequence data
Biological Unit for 2XPK: dimeric; determined by author and by software (PISA)
Molecular Components in 2XPK
Label
Count
Molecule
Proteins (2 molecules)
A
B
2
O-glcnacase Nagj
(Gene symbol:
CPF_RS07030
)
Chemicals and Non-standard biopolymers (2 molecules)
1
2
N-[(5R,6R,7R,8S)-6,7-DIHYDROXY-5-(HYDROXYMETHYL)-2-(2-PHENYLETHYL)-5,6,7,8-TETRAHYDROIMIDAZO[1,2-A]PYRIDIN-8-YL]-3-SULFANYLPROPANAMIDE
* Click molecule labels to explore molecular sequence information.
Citing MMDB
Madej T, Lanczycki CJ, Zhang D, Thiessen PA, Geer RC, Marchler-Bauer A, Bryant SH.
"
MMDB and VAST+: tracking structural similarities between macromolecular complexes.
Nucleic Acids Res. 2014 Jan; 42(Database issue)
:D297-303