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Items: 1 to 20 of 534

1.

G protein-coupled receptors--recent advances.

Latek D, Modzelewska A, Trzaskowski B, Palczewski K, Filipek S.

Acta Biochim Pol. 2012;59(4):515-29. Epub 2012 Dec 18. Review.

2.

Agonist-induced conformational changes in bovine rhodopsin: insight into activation of G-protein-coupled receptors.

Bhattacharya S, Hall SE, Vaidehi N.

J Mol Biol. 2008 Oct 3;382(2):539-55. doi: 10.1016/j.jmb.2008.06.084. Epub 2008 Jul 7.

PMID:
18638482
3.

X-ray structure breakthroughs in the GPCR transmembrane region.

Topiol S, Sabio M.

Biochem Pharmacol. 2009 Jul 1;78(1):11-20. doi: 10.1016/j.bcp.2009.02.012. Epub 2009 Feb 27. Review.

PMID:
19447219
4.

Structural basis for ligand binding and specificity in adrenergic receptors: implications for GPCR-targeted drug discovery.

Huber T, Menon S, Sakmar TP.

Biochemistry. 2008 Oct 21;47(42):11013-23. doi: 10.1021/bi800891r. Epub 2008 Sep 27.

PMID:
18821775
5.

Relevance of rhodopsin studies for GPCR activation.

Deupi X.

Biochim Biophys Acta. 2014 May;1837(5):674-82. doi: 10.1016/j.bbabio.2013.09.002. Epub 2013 Sep 13. Review.

6.

Structure-Based Prediction of G-Protein-Coupled Receptor Ligand Function: A β-Adrenoceptor Case Study.

Kooistra AJ, Leurs R, de Esch IJ, de Graaf C.

J Chem Inf Model. 2015 May 26;55(5):1045-61. doi: 10.1021/acs.jcim.5b00066. Epub 2015 May 1.

PMID:
25848966
7.

The role of protein dynamics in GPCR function: insights from the β2AR and rhodopsin.

Manglik A, Kobilka B.

Curr Opin Cell Biol. 2014 Apr;27:136-43. doi: 10.1016/j.ceb.2014.01.008. Epub 2014 Feb 17. Review.

8.

A structural snapshot of the rhodopsin-arrestin complex.

Kang Y, Gao X, Zhou XE, He Y, Melcher K, Xu HE.

FEBS J. 2016 Mar;283(5):816-21. doi: 10.1111/febs.13561. Epub 2015 Nov 7. Review.

9.

Molecular dynamics simulations of the effect of the G-protein and diffusible ligands on the β2-adrenergic receptor.

Goetz A, Lanig H, Gmeiner P, Clark T.

J Mol Biol. 2011 Dec 9;414(4):611-23. doi: 10.1016/j.jmb.2011.10.015. Epub 2011 Oct 20.

PMID:
22037586
10.

Structural features of β2 adrenergic receptor: crystal structures and beyond.

Bang I, Choi HJ.

Mol Cells. 2015;38(2):105-11. doi: 10.14348/molcells.2015.2301. Epub 2014 Dec 24. Review.

11.

Restructuring G-protein- coupled receptor activation.

Audet M, Bouvier M.

Cell. 2012 Sep 28;151(1):14-23. doi: 10.1016/j.cell.2012.09.003. Review.

12.

Understanding the GPCR biased signaling through G protein and arrestin complex structures.

Zhou XE, Melcher K, Xu HE.

Curr Opin Struct Biol. 2017 Aug;45:150-159. doi: 10.1016/j.sbi.2017.05.004. Epub 2017 May 27. Review.

PMID:
28558341
13.

Conformational complexity of G-protein-coupled receptors.

Kobilka BK, Deupi X.

Trends Pharmacol Sci. 2007 Aug;28(8):397-406. Epub 2007 Jul 13. Review.

PMID:
17629961
14.

A beta-arrestin binding determinant common to the second intracellular loops of rhodopsin family G protein-coupled receptors.

Marion S, Oakley RH, Kim KM, Caron MG, Barak LS.

J Biol Chem. 2006 Feb 3;281(5):2932-8. Epub 2005 Nov 30.

15.

GPCR agonist binding revealed by modeling and crystallography.

Katritch V, Abagyan R.

Trends Pharmacol Sci. 2011 Nov;32(11):637-43. doi: 10.1016/j.tips.2011.08.001. Epub 2011 Sep 6.

16.

Structural insights into agonist-induced activation of G-protein-coupled receptors.

Deupi X, Standfuss J.

Curr Opin Struct Biol. 2011 Aug;21(4):541-51. doi: 10.1016/j.sbi.2011.06.002. Epub 2011 Jun 30. Review.

PMID:
21723721
17.

FoldGPCR: structure prediction protocol for the transmembrane domain of G protein-coupled receptors from class A.

Michino M, Chen J, Stevens RC, Brooks CL 3rd.

Proteins. 2010 Aug 1;78(10):2189-201. doi: 10.1002/prot.22731.

18.

Conformational changes of G protein-coupled receptors during their activation by agonist binding.

Bissantz C.

J Recept Signal Transduct Res. 2003;23(2-3):123-53. Review.

PMID:
14626443
19.

Toward the active conformations of rhodopsin and the beta2-adrenergic receptor.

Gouldson PR, Kidley NJ, Bywater RP, Psaroudakis G, Brooks HD, Diaz C, Shire D, Reynolds CA.

Proteins. 2004 Jul 1;56(1):67-84.

PMID:
15162487
20.

Activation of G-protein-coupled receptors: a common molecular mechanism.

Karnik SS, Gogonea C, Patil S, Saad Y, Takezako T.

Trends Endocrinol Metab. 2003 Nov;14(9):431-7. Review.

PMID:
14580763

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