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Items: 1 to 20 of 138

1.

Diversity and modularity of G protein-coupled receptor structures.

Katritch V, Cherezov V, Stevens RC.

Trends Pharmacol Sci. 2012 Jan;33(1):17-27. doi: 10.1016/j.tips.2011.09.003. Epub 2011 Oct 25. Review.

2.

X-ray structure breakthroughs in the GPCR transmembrane region.

Topiol S, Sabio M.

Biochem Pharmacol. 2009 Jul 1;78(1):11-20. doi: 10.1016/j.bcp.2009.02.012. Epub 2009 Feb 27. Review.

PMID:
19447219
3.

Agonist-induced conformational changes in bovine rhodopsin: insight into activation of G-protein-coupled receptors.

Bhattacharya S, Hall SE, Vaidehi N.

J Mol Biol. 2008 Oct 3;382(2):539-55. doi: 10.1016/j.jmb.2008.06.084. Epub 2008 Jul 7.

PMID:
18638482
4.

The year in G protein-coupled receptor research.

Millar RP, Newton CL.

Mol Endocrinol. 2010 Jan;24(1):261-74. doi: 10.1210/me.2009-0473. Epub 2009 Dec 17. Review.

5.

The GPCR crystallography boom: providing an invaluable source of structural information and expanding the scope of homology modeling.

Costanzi S, Wang K.

Adv Exp Med Biol. 2014;796:3-13. doi: 10.1007/978-94-007-7423-0_1. Review.

PMID:
24158798
6.

Modern homology modeling of G-protein coupled receptors: which structural template to use?

Mobarec JC, Sanchez R, Filizola M.

J Med Chem. 2009 Aug 27;52(16):5207-16. doi: 10.1021/jm9005252.

7.

A structural chemogenomics analysis of aminergic GPCRs: lessons for histamine receptor ligand design.

Kooistra AJ, Kuhne S, de Esch IJ, Leurs R, de Graaf C.

Br J Pharmacol. 2013 Sep;170(1):101-26. doi: 10.1111/bph.12248.

8.

Structural studies of G protein-coupled receptors.

Lu M, Wu B.

IUBMB Life. 2016 Nov;68(11):894-903. doi: 10.1002/iub.1578. Epub 2016 Oct 20. Review.

9.

Comparative sequence and structural analyses of G-protein-coupled receptor crystal structures and implications for molecular models.

Worth CL, Kleinau G, Krause G.

PLoS One. 2009 Sep 16;4(9):e7011. doi: 10.1371/journal.pone.0007011.

10.

Structural diversity of G protein-coupled receptors and significance for drug discovery.

Lagerström MC, Schiöth HB.

Nat Rev Drug Discov. 2008 Apr;7(4):339-57. doi: 10.1038/nrd2518. Review. Erratum in: Nat Rev Drug Discov. 2008 Jun;7(6):542.

PMID:
18382464
11.

Structural insights into ligand recognition and selectivity for classes A, B, and C GPCRs.

Lee SM, Booe JM, Pioszak AA.

Eur J Pharmacol. 2015 Sep 15;763(Pt B):196-205. doi: 10.1016/j.ejphar.2015.05.013. Epub 2015 May 14. Review.

12.

Structural basis for ligand binding and specificity in adrenergic receptors: implications for GPCR-targeted drug discovery.

Huber T, Menon S, Sakmar TP.

Biochemistry. 2008 Oct 21;47(42):11013-23. doi: 10.1021/bi800891r. Epub 2008 Sep 27.

PMID:
18821775
13.

Structure modeling of all identified G protein-coupled receptors in the human genome.

Zhang Y, Devries ME, Skolnick J.

PLoS Comput Biol. 2006 Feb;2(2):e13. Epub 2006 Feb 17. Erratum in: PLoS Comput Biol. 2006 Mar;2(3):e29.

14.

The impact of GPCR structures on pharmacology and structure-based drug design.

Congreve M, Marshall F.

Br J Pharmacol. 2010 Mar;159(5):986-96. doi: 10.1111/j.1476-5381.2009.00476.x. Epub 2009 Nov 13. Review.

15.

Chemokine receptors and other G protein-coupled receptors.

Lodowski DT, Palczewski K.

Curr Opin HIV AIDS. 2009 Mar;4(2):88-95. doi: 10.1097/COH.0b013e3283223d8d. Review.

16.

Structure and dynamics of G-protein coupled receptors.

Vaidehi N, Bhattacharya S, Larsen AB.

Adv Exp Med Biol. 2014;796:37-54. doi: 10.1007/978-94-007-7423-0_3. Review.

PMID:
24158800
17.

Structure-function of the G protein-coupled receptor superfamily.

Katritch V, Cherezov V, Stevens RC.

Annu Rev Pharmacol Toxicol. 2013;53:531-56. doi: 10.1146/annurev-pharmtox-032112-135923. Epub 2012 Nov 8. Review.

18.

GPCR crystal structures: Medicinal chemistry in the pocket.

Shonberg J, Kling RC, Gmeiner P, Löber S.

Bioorg Med Chem. 2015 Jul 15;23(14):3880-906. doi: 10.1016/j.bmc.2014.12.034. Epub 2014 Dec 24. Review.

PMID:
25638496
19.

Importance of the extracellular loops in G protein-coupled receptors for ligand recognition and receptor activation.

Peeters MC, van Westen GJ, Li Q, IJzerman AP.

Trends Pharmacol Sci. 2011 Jan;32(1):35-42. doi: 10.1016/j.tips.2010.10.001. Review.

PMID:
21075459

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