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Noncanonical sortase-mediated assembly of pilus type 2b in group B Streptococcus.

Lazzarin M, Cozzi R, Malito E, Martinelli M, D'Onofrio M, Maione D, Margarit I, Rinaudo CD.

FASEB J. 2015 Nov;29(11):4629-40. doi: 10.1096/fj.15-272500. Epub 2015 Jul 22.


A structural snapshot of type II pilus formation in Streptococcus pneumoniae.

Shaik MM, Lombardi C, Maragno Trindade D, Fenel D, Schoehn G, Di Guilmi AM, Dessen A.

J Biol Chem. 2015 Sep 11;290(37):22581-92. doi: 10.1074/jbc.M115.647834. Epub 2015 Jul 21.


Structural and biochemical analyses of a Clostridium perfringens sortase D transpeptidase.

Suryadinata R, Seabrook SA, Adams TE, Nuttall SD, Peat TS.

Acta Crystallogr D Biol Crystallogr. 2015 Jul;71(Pt 7):1505-13. doi: 10.1107/S1399004715009219. Epub 2015 Jun 30.


Molecular basis of Streptococcus mutans sortase A inhibition by the flavonoid natural product trans-chalcone.

Wallock-Richards DJ, Marles-Wright J, Clarke DJ, Maitra A, Dodds M, Hanley B, Campopiano DJ.

Chem Commun (Camb). 2015 Jul 4;51(52):10483-5. doi: 10.1039/c5cc01816a.


Molecular features of the sortase enzyme family.

Bradshaw WJ, Davies AH, Chambers CJ, Roberts AK, Shone CC, Acharya KR.

FEBS J. 2015 Jun;282(11):2097-114. doi: 10.1111/febs.13288. Epub 2015 Apr 24. Review.


Structure and function of a Clostridium difficile sortase enzyme.

Chambers CJ, Roberts AK, Shone CC, Acharya KR.

Sci Rep. 2015 Mar 24;5:9449. doi: 10.1038/srep09449.


Discovery and structure-activity relationship studies of irreversible benzisothiazolinone-based inhibitors against Staphylococcus aureus sortase A transpeptidase.

Zhulenkovs D, Rudevica Z, Jaudzems K, Turks M, Leonchiks A.

Bioorg Med Chem. 2014 Nov 1;22(21):5988-6003. doi: 10.1016/j.bmc.2014.09.011. Epub 2014 Sep 16.


Structural and computational studies of the Staphylococcus aureus sortase B-substrate complex reveal a substrate-stabilized oxyanion hole.

Jacobitz AW, Wereszczynski J, Yi SW, Amer BR, Huang GL, Nguyen AV, Sawaya MR, Jung ME, McCammon JA, Clubb RT.

J Biol Chem. 2014 Mar 28;289(13):8891-902. doi: 10.1074/jbc.M113.509273. Epub 2014 Feb 11.


Structural basis for group B streptococcus pilus 1 sortases C regulation and specificity.

Cozzi R, Prigozhin D, Rosini R, Abate F, Bottomley MJ, Grandi G, Telford JL, Rinaudo CD, Maione D, Alber T.

PLoS One. 2012;7(11):e49048. doi: 10.1371/journal.pone.0049048. Epub 2012 Nov 8.


Solution structure of the sortase required for efficient production of infectious Bacillus anthracis spores.

Robson SA, Jacobitz AW, Phillips ML, Clubb RT.

Biochemistry. 2012 Oct 9;51(40):7953-63. doi: 10.1021/bi300867t. Epub 2012 Sep 27.


Crystallization and preliminary X-ray diffraction studies of sortase A from Streptococcus pneumoniae.

Misra A, Biswas T, Das S, Marathe U, Sehgal D, Roy RP, Suryanarayanarao R.

Acta Crystallogr Sect F Struct Biol Cryst Commun. 2011 Oct 1;67(Pt 10):1195-8. doi: 10.1107/S1744309111029952. Epub 2011 Sep 24.


Sortase enzymes in Gram-positive bacteria.

Spirig T, Weiner EM, Clubb RT.

Mol Microbiol. 2011 Dec;82(5):1044-59. doi: 10.1111/j.1365-2958.2011.07887.x. Epub 2011 Nov 7. Review.


Structural differences between the Streptococcus agalactiae housekeeping and pilus-specific sortases: SrtA and SrtC1.

Khare B, Krishnan V, Rajashankar KR, I-Hsiu H, Xin M, Ton-That H, Narayana SV.

PLoS One. 2011;6(8):e22995. doi: 10.1371/journal.pone.0022995. Epub 2011 Aug 30.


Structure of the sortase AcSrtC-1 from Actinomyces oris.

Persson K.

Acta Crystallogr D Biol Crystallogr. 2011 Mar;67(Pt 3):212-7. doi: 10.1107/S0907444911004215. Epub 2011 Feb 15.


Structure analysis and site-directed mutagenesis of defined key residues and motives for pilus-related sortase C1 in group B Streptococcus.

Cozzi R, Malito E, Nuccitelli A, D'Onofrio M, Martinelli M, Ferlenghi I, Grandi G, Telford JL, Maione D, Rinaudo CD.

FASEB J. 2011 Jun;25(6):1874-86. doi: 10.1096/fj.10-174797. Epub 2011 Feb 25.


Architects at the bacterial surface - sortases and the assembly of pili with isopeptide bonds.

Hendrickx AP, Budzik JM, Oh SY, Schneewind O.

Nat Rev Microbiol. 2011 Mar;9(3):166-76. doi: 10.1038/nrmicro2520. Review.


Crystal structure of Spy0129, a Streptococcus pyogenes class B sortase involved in pilus assembly.

Kang HJ, Coulibaly F, Proft T, Baker EN.

PLoS One. 2011 Jan 11;6(1):e15969. doi: 10.1371/journal.pone.0015969.


Sortase transpeptidases: insights into mechanism, substrate specificity, and inhibition.

Clancy KW, Melvin JA, McCafferty DG.

Biopolymers. 2010;94(4):385-96. doi: 10.1002/bip.21472. Review. Erratum in: Biopolymers. 2010;94(5):681.


The Sortase A enzyme that attaches proteins to the cell wall of Bacillus anthracis contains an unusual active site architecture.

Weiner EM, Robson S, Marohn M, Clubb RT.

J Biol Chem. 2010 Jul 23;285(30):23433-43. doi: 10.1074/jbc.M110.135434. Epub 2010 May 19.


Sortase activity is controlled by a flexible lid in the pilus biogenesis mechanism of gram-positive pathogens.

Manzano C, Izoré T, Job V, Di Guilmi AM, Dessen A.

Biochemistry. 2009 Nov 10;48(44):10549-57. doi: 10.1021/bi901261y.


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