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The evolution of the GPCR signaling system in eukaryotes: modularity, conservation, and the transition to metazoan multicellularity.

de Mendoza A, Sebé-Pedrós A, Ruiz-Trillo I.

Genome Biol Evol. 2014 Mar;6(3):606-19. doi: 10.1093/gbe/evu038.


Structural Aspects of GPCR-G Protein Coupling.

Chung KY.

Toxicol Res. 2013 Sep;29(3):149-55. doi: 10.5487/TR.2013.29.3.149.


From three-dimensional GPCR structure to rational ligand discovery.

Kooistra AJ, Leurs R, de Esch IJ, de Graaf C.

Adv Exp Med Biol. 2014;796:129-57. doi: 10.1007/978-94-007-7423-0_7. Review.


Molecular signatures of G-protein-coupled receptors.

Venkatakrishnan AJ, Deupi X, Lebon G, Tate CG, Schertler GF, Babu MM.

Nature. 2013 Feb 14;494(7436):185-94. doi: 10.1038/nature11896. Review.


G protein-coupled receptors--recent advances.

Latek D, Modzelewska A, Trzaskowski B, Palczewski K, Filipek S.

Acta Biochim Pol. 2012;59(4):515-29. Epub 2012 Dec 18. Review.


The GPCR Network: a large-scale collaboration to determine human GPCR structure and function.

Stevens RC, Cherezov V, Katritch V, Abagyan R, Kuhn P, Rosen H, Wüthrich K.

Nat Rev Drug Discov. 2013 Jan;12(1):25-34. doi: 10.1038/nrd3859. Epub 2012 Dec 14. Review.


Structure-function of the G protein-coupled receptor superfamily.

Katritch V, Cherezov V, Stevens RC.

Annu Rev Pharmacol Toxicol. 2013;53:531-56. doi: 10.1146/annurev-pharmtox-032112-135923. Epub 2012 Nov 8. Review.


G protein-coupled receptor deorphanizations.

Civelli O, Reinscheid RK, Zhang Y, Wang Z, Fredriksson R, Schiöth HB.

Annu Rev Pharmacol Toxicol. 2013;53:127-46. doi: 10.1146/annurev-pharmtox-010611-134548. Epub 2012 Sep 28. Review.


Emerging opportunities for allosteric modulation of G-protein coupled receptors.

Wang CI, Lewis RJ.

Biochem Pharmacol. 2013 Jan 15;85(2):153-62. doi: 10.1016/j.bcp.2012.09.001. Epub 2012 Sep 11. Review.


Effect of schizophrenia risk-associated alleles in SREB2 (GPR85) on functional MRI phenotypes in healthy volunteers.

Radulescu E, Sambataro F, Mattay VS, Callicott JH, Straub RE, Matsumoto M, Weinberger DR, Marenco S.

Neuropsychopharmacology. 2013 Jan;38(2):341-9. doi: 10.1038/npp.2012.184. Epub 2012 Sep 12.


SREB2/GPR85, a schizophrenia risk factor, negatively regulates hippocampal adult neurogenesis and neurogenesis-dependent learning and memory.

Chen Q, Kogan JH, Gross AK, Zhou Y, Walton NM, Shin R, Heusner CL, Miyake S, Tajinda K, Tamura K, Matsumoto M.

Eur J Neurosci. 2012 Sep;36(5):2597-608. doi: 10.1111/j.1460-9568.2012.08180.x. Epub 2012 Jun 15.


Structure-based drug screening for G-protein-coupled receptors.

Shoichet BK, Kobilka BK.

Trends Pharmacol Sci. 2012 May;33(5):268-72. doi: 10.1016/ Epub 2012 Apr 13. Review.


The origin of GPCRs: identification of mammalian like Rhodopsin, Adhesion, Glutamate and Frizzled GPCRs in fungi.

Krishnan A, Almén MS, Fredriksson R, Schiöth HB.

PLoS One. 2012;7(1):e29817. doi: 10.1371/journal.pone.0029817. Epub 2012 Jan 4.


Diversity and modularity of G protein-coupled receptor structures.

Katritch V, Cherezov V, Stevens RC.

Trends Pharmacol Sci. 2012 Jan;33(1):17-27. doi: 10.1016/ Epub 2011 Oct 25. Review.


Structural insights into adrenergic receptor function and pharmacology.

Kobilka BK.

Trends Pharmacol Sci. 2011 Apr;32(4):213-8. doi: 10.1016/ Epub 2011 Mar 15. Review.


Identification and relative quantitation of an orphan G-protein coupled receptor SREB2 (GPR85) protein in tissue using a linear ion trap mass spectrometer.

Yuri M, Hiramoto M, Naito M, Matsumoto M, Matsumoto S, Morita S, Mori K, Yokota H, Teramura T.

J Proteome Res. 2011 May 6;10(5):2658-63. doi: 10.1021/pr101252p. Epub 2011 Mar 25.


Energy landscapes as a tool to integrate GPCR structure, dynamics, and function.

Deupi X, Kobilka BK.

Physiology (Bethesda). 2010 Oct;25(5):293-303. doi: 10.1152/physiol.00002.2010. Review.


Signaling through G protein coupled receptors.

Tuteja N.

Plant Signal Behav. 2009 Oct;4(10):942-7. Epub 2009 Oct 14. Review.


Comparative sequence and structural analyses of G-protein-coupled receptor crystal structures and implications for molecular models.

Worth CL, Kleinau G, Krause G.

PLoS One. 2009 Sep 16;4(9):e7011. doi: 10.1371/journal.pone.0007011.


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