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Items: 1 to 20 of 37

1.

The evolution of the GPCR signaling system in eukaryotes: modularity, conservation, and the transition to metazoan multicellularity.

de Mendoza A, Sebé-Pedrós A, Ruiz-Trillo I.

Genome Biol Evol. 2014 Mar;6(3):606-19. doi: 10.1093/gbe/evu038.

2.

The role of protein dynamics in GPCR function: insights from the β2AR and rhodopsin.

Manglik A, Kobilka B.

Curr Opin Cell Biol. 2014 Apr;27:136-43. doi: 10.1016/j.ceb.2014.01.008. Epub 2014 Feb 17. Review.

3.

Structure-based drug design for G protein-coupled receptors.

Congreve M, Dias JM, Marshall FH.

Prog Med Chem. 2014;53:1-63. doi: 10.1016/B978-0-444-63380-4.00001-9. Review.

PMID:
24418607
4.

Structural Aspects of GPCR-G Protein Coupling.

Chung KY.

Toxicol Res. 2013 Sep;29(3):149-55. doi: 10.5487/TR.2013.29.3.149.

5.

GPCRDB: an information system for G protein-coupled receptors.

Isberg V, Vroling B, van der Kant R, Li K, Vriend G, Gloriam D.

Nucleic Acids Res. 2014 Jan;42(Database issue):D422-5. doi: 10.1093/nar/gkt1255. Epub 2013 Dec 3.

6.

From three-dimensional GPCR structure to rational ligand discovery.

Kooistra AJ, Leurs R, de Esch IJ, de Graaf C.

Adv Exp Med Biol. 2014;796:129-57. doi: 10.1007/978-94-007-7423-0_7. Review.

PMID:
24158804
7.

Structure and dynamics of G-protein coupled receptors.

Vaidehi N, Bhattacharya S, Larsen AB.

Adv Exp Med Biol. 2014;796:37-54. doi: 10.1007/978-94-007-7423-0_3. Review.

PMID:
24158800
8.

An analysis of oligomerization interfaces in transmembrane proteins.

Duarte JM, Biyani N, Baskaran K, Capitani G.

BMC Struct Biol. 2013 Oct 17;13:21. doi: 10.1186/1472-6807-13-21.

9.

Eukaryotic G protein signaling evolved to require G protein-coupled receptors for activation.

Bradford W, Buckholz A, Morton J, Price C, Jones AM, Urano D.

Sci Signal. 2013 May 21;6(276):ra37. doi: 10.1126/scisignal.2003768.

10.

G-protein-coupled receptor structure, ligand binding and activation as studied by solid-state NMR spectroscopy.

Ding X, Zhao X, Watts A.

Biochem J. 2013 Mar 15;450(3):443-57. doi: 10.1042/BJ20121644. Review. Erratum in: Biochem J. 2013 Apr 15;451(2):343.

PMID:
23445222
11.

Molecular signatures of G-protein-coupled receptors.

Venkatakrishnan AJ, Deupi X, Lebon G, Tate CG, Schertler GF, Babu MM.

Nature. 2013 Feb 14;494(7436):185-94. doi: 10.1038/nature11896. Review.

PMID:
23407534
12.

G protein-coupled receptors--recent advances.

Latek D, Modzelewska A, Trzaskowski B, Palczewski K, Filipek S.

Acta Biochim Pol. 2012;59(4):515-29. Epub 2012 Dec 18. Review.

13.

The GPCR Network: a large-scale collaboration to determine human GPCR structure and function.

Stevens RC, Cherezov V, Katritch V, Abagyan R, Kuhn P, Rosen H, Wüthrich K.

Nat Rev Drug Discov. 2013 Jan;12(1):25-34. doi: 10.1038/nrd3859. Epub 2012 Dec 14. Review.

14.

Structure-function of the G protein-coupled receptor superfamily.

Katritch V, Cherezov V, Stevens RC.

Annu Rev Pharmacol Toxicol. 2013;53:531-56. doi: 10.1146/annurev-pharmtox-032112-135923. Epub 2012 Nov 8. Review.

15.

G protein-coupled receptor deorphanizations.

Civelli O, Reinscheid RK, Zhang Y, Wang Z, Fredriksson R, Schiöth HB.

Annu Rev Pharmacol Toxicol. 2013;53:127-46. doi: 10.1146/annurev-pharmtox-010611-134548. Epub 2012 Sep 28. Review.

16.

Structure-based drug screening for G-protein-coupled receptors.

Shoichet BK, Kobilka BK.

Trends Pharmacol Sci. 2012 May;33(5):268-72. doi: 10.1016/j.tips.2012.03.007. Epub 2012 Apr 13. Review.

17.

The origin of GPCRs: identification of mammalian like Rhodopsin, Adhesion, Glutamate and Frizzled GPCRs in fungi.

Krishnan A, Almén MS, Fredriksson R, Schiöth HB.

PLoS One. 2012;7(1):e29817. doi: 10.1371/journal.pone.0029817. Epub 2012 Jan 4.

18.

Diversity and modularity of G protein-coupled receptor structures.

Katritch V, Cherezov V, Stevens RC.

Trends Pharmacol Sci. 2012 Jan;33(1):17-27. doi: 10.1016/j.tips.2011.09.003. Epub 2011 Oct 25. Review.

19.

Yeast pheromone receptor genes STE2 and STE3 are differently regulated at the transcription and polyadenylation level.

Di Segni G, Gastaldi S, Zamboni M, Tocchini-Valentini GP.

Proc Natl Acad Sci U S A. 2011 Oct 11;108(41):17082-6. doi: 10.1073/pnas.1114648108. Epub 2011 Oct 3.

20.

Structural insights into adrenergic receptor function and pharmacology.

Kobilka BK.

Trends Pharmacol Sci. 2011 Apr;32(4):213-8. doi: 10.1016/j.tips.2011.02.005. Epub 2011 Mar 15. Review.

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