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Items: 6


Stk10, a new member of the polo-like kinase kinase family highly expressed in hematopoietic tissue.

Walter SA, Cutler RE Jr, Martinez R, Gishizky M, Hill RJ.

J Biol Chem. 2003 May 16;278(20):18221-8. Epub 2003 Mar 13.


Opposing roles of serine/threonine kinases MEKK1 and LOK in regulating the CD28 responsive element in T-cells.

Tao L, Wadsworth S, Mercer J, Mueller C, Lynn K, Siekierka J, August A.

Biochem J. 2002 Apr 1;363(Pt 1):175-82.


Deficiency of a STE20/PAK family kinase LOK leads to the acceleration of LFA-1 clustering and cell adhesion of activated lymphocytes.

Endo J, Toyama-Sorimachi N, Taya C, Kuramochi-Miyagawa S, Nagata K, Kuida K, Takashi T, Yonekawa H, Yoshizawa Y, Miyasaka N, Karasuyama H.

FEBS Lett. 2000 Feb 25;468(2-3):234-8.


Molecular cloning of the human gene STK10 encoding lymphocyte-oriented kinase, and comparative chromosomal mapping of the human, mouse, and rat homologues.

Kuramochi S, Matsuda Y, Okamoto M, Kitamura F, Yonekawa H, Karasuyama H.

Immunogenetics. 1999 May;49(5):369-75.


LOK is a novel mouse STE20-like protein kinase that is expressed predominantly in lymphocytes.

Kuramochi S, Moriguchi T, Kuida K, Endo J, Semba K, Nishida E, Karasuyama H.

J Biol Chem. 1997 Sep 5;272(36):22679-84.

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