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HomoloGene:48350. Gene conserved in Boreoeutheria Download , Links
Genes identified as putative homologs of one another during the construction of HomoloGene.

Proteins used in sequence comparisons and their conserved domain architectures.

INSL5,  H.sapiens
insulin-like 5
135 aa
INSL5,  P.troglodytes
insulin-like 5
135 aa
INSL5,  M.mulatta
insulin-like 5
135 aa
INSL5,  B.taurus
insulin-like 5
135 aa
Insl5,  M.musculus
insulin-like 5
135 aa

Protein Alignments
Protein multiple alignment, pairwise similarity scores and evolutionary distances.

Show Multiple Alignment

Show Pairwise Alignment Scores

Pairwise alignments generated using BLAST
Regenerate Alignments

Articles associated with genes and sequences of this homology group.

INSL5 may be a unique marker of colorectal endocrine cells and neuroendocrine tumors.
Mashima H, et al. Biochem Biophys Res Commun 432, 586-92 (2013).
INSL5 is a high affinity specific agonist for GPCR142 (GPR100).
Liu C, et al. J Biol Chem 280, 292-300 (2005).

Conserved Domains
Conserved Domains from CDD found in protein sequences by rpsblast searching.
IlGF_like (cl02453)
  Insulin/insulin-like growth factor/relaxin family; insulin family of proteins. Members include a number of active peptides which are evolutionary related including insulin, relaxin, prorelaxin, insulin-like growth factors I and II, mammalian Leydig ...

Related Homology Resources
Links to curated and computed homology information found in other databases.
Orthology group for M.musculus Insl5 includes H.sapiens INSL5.




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