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HomoloGene:87809. Gene conserved in Euteleostomi Download , Links
Genes
Genes identified as putative homologs of one another during the construction of HomoloGene.

Proteins
Proteins used in sequence comparisons and their conserved domain architectures.

RUFY3,  H.sapiens
RUN and FYVE domain containing 3
NP_001032519.1
620 aa
RUFY3,  P.troglodytes
RUN and FYVE domain containing 3
XP_001160004.1
620 aa
RUFY3,  C.lupus
RUN and FYVE domain containing 3
XP_005628330.1
638 aa
Rufy3,  M.musculus
RUN and FYVE domain containing 3
NP_081806.1
469 aa
Rufy3,  R.norvegicus
RUN and FYVE domain containing 3
NP_001020298.1
469 aa
RUFY3,  G.gallus
RUN and FYVE domain containing 3
XP_004941234.1
645 aa
rufy3,  X.tropicalis
RUN and FYVE domain containing 3
NP_001072214.1
469 aa
rufy3,  D.rerio
RUN and FYVE domain containing 3
NP_001014357.1
470 aa


Protein Alignments
Protein multiple alignment, pairwise similarity scores and evolutionary distances.

Show Multiple Alignment

Show Pairwise Alignment Scores

Pairwise alignments generated using BLAST
Regenerate Alignments




Publications
Articles associated with genes and sequences of this homology group.

Rab5(Q79L) interacts with the carboxyl terminus of RUFY3.
Yoshida H, et al. Int J Biol Sci 6, 187-9 (2010).
Crystal structure of the RUN domain of the RAP2-interacting protein x.
Kukimoto-Niino M, et al. J Biol Chem 281, 31843-53 (2006).
eXPRESSION: an in silico tool to predict patterns of gene expression.
Ferguson DA, et al. Gene Expr Patterns 5, 619-28 (2005).



Conserved Domains
Conserved Domains from CDD found in protein sequences by rpsblast searching.
RUN (pfam02759)
  RUN domain.
RUN (cl02689)
  RUN domain.
BAR (cl12013)
  The Bin/Amphiphysin/Rvs (BAR) domain, a dimerization module that binds membranes and detects membrane curvature.
FYVE (cl17764)
  FYVE domain; Zinc-binding domain; targets proteins to membrane lipids via interaction with phosphatidylinositol-3-phosphate, PI3P; present in Fab1, YOTB, Vac1, and EEA1.
MreC (cl19252)
  rod shape-determining protein MreC.



Related Homology Resources
Links to curated and computed homology information found in other databases.
Orthology group for M.musculus Rufy3 includes H.sapiens RUFY3 and R.norvegicus Rufy3.

 

 

 

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