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HomoloGene:20834. Gene conserved in Opisthokonta Download , Links
Genes
Genes identified as putative homologs of one another during the construction of HomoloGene.

Proteins
Proteins used in sequence comparisons and their conserved domain architectures.

KAT2B,  H.sapiens
K(lysine) acetyltransferase 2B
NP_003875.3
832 aa
KAT2B,  P.troglodytes
K(lysine) acetyltransferase 2B
XP_516321.3
927 aa
LOC698283,  M.mulatta
histone acetyltransferase KAT2B-like
XP_001086807.1
858 aa
KAT2B,  C.lupus
K(lysine) acetyltransferase 2B
XP_005634698.1
777 aa
KAT2B,  B.taurus
K(lysine) acetyltransferase 2B
XP_002684762.1
826 aa
Kat2b,  M.musculus
K(lysine) acetyltransferase 2B
NP_064389.2
813 aa
Pcaf,  R.norvegicus
p300/CBP-associated factor
XP_003750665.2
674 aa
KAT2B,  G.gallus
K(lysine) acetyltransferase 2B
XP_426001.4
839 aa
kat2b,  X.tropicalis
K(lysine) acetyltransferase 2B
XP_002932452.1
816 aa
kat2b,  D.rerio
K(lysine) acetyltransferase 2B
NP_001038499.1
796 aa
pcaf-1,  C.elegans
pcaf-1
NP_491173.1
767 aa
GCN5,  S.cerevisiae
GCN5
NP_011768.1
439 aa
KLLA0A05115g,  K.lactis
KLLA0A05115g
XP_451225.1
516 aa
AGOS_AER297C,  E.gossypii
AGOS_AER297C
NP_985154.1
452 aa
gcn5,  S.pombe
gcn5
NP_594807.1
454 aa
MGG_03677,  M.oryzae
MGG_03677
XP_003716207.1
400 aa
NCU10847,  N.crassa
NCU10847
XP_001728480.1
422 aa


Protein Alignments
Protein multiple alignment, pairwise similarity scores and evolutionary distances.

Show Multiple Alignment

Show Pairwise Alignment Scores

Pairwise alignments generated using BLAST
Regenerate Alignments




Publications
Articles associated with genes and sequences of this homology group.

Lysine acetyltransferase PCAF is a key regulator of arteriogenesis.
Bastiaansen AJ, et al. Arterioscler Thromb Vasc Biol 33, 1902-10 (2013).
[Expression of PCAF in hepatocellular carcinoma and its clinical significance].
Tuo H, et al. Xi Bao Yu Fen Zi Mian Yi Xue Za Zhi 29, 297-300 (2013).



Conserved Domains
Conserved Domains from CDD found in protein sequences by rpsblast searching.
PCAF_N (pfam06466)
  PCAF (P300/CBP-associated factor) N-terminal domain.
Acetyltransf_1 (pfam00583)
  Acetyltransferase (GNAT) family.
Bromodomain (cl02556)
  Bromodomain. Bromodomains are found in many chromatin-associated proteins and in nuclear histone acetyltransferases. They interact specifically with acetylated lysine.
NAT_SF (cl17182)
  N-Acyltransferase superfamily: Various enzymes that characteristically catalyze the transfer of an acyl group to a substrate.



Related Homology Resources
Links to curated and computed homology information found in other databases.
Orthology group for M.musculus Kat2b includes H.sapiens KAT2B.


 

 

 

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