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HomoloGene:1880. Gene conserved in Euteleostomi Download , Links
Genes
Genes identified as putative homologs of one another during the construction of HomoloGene.

Proteins
Proteins used in sequence comparisons and their conserved domain architectures.

GPNMB,  H.sapiens
glycoprotein (transmembrane) nmb
NP_001005340.1
572 aa
GPNMB,  P.troglodytes
glycoprotein (transmembrane) nmb
XP_001157101.2
572 aa
GPNMB,  M.mulatta
glycoprotein (transmembrane) nmb
XP_001099643.2
608 aa
GPNMB,  C.lupus
glycoprotein (transmembrane) nmb
XP_539472.2
554 aa
GPNMB,  B.taurus
glycoprotein (transmembrane) nmb
NP_001033154.1
555 aa
Gpnmb,  M.musculus
glycoprotein (transmembrane) nmb
NP_444340.3
574 aa
Gpnmb,  R.norvegicus
glycoprotein (transmembrane) nmb
NP_579832.1
572 aa
GPNMB,  G.gallus
glycoprotein (transmembrane) nmb
XP_425991.2
559 aa
gpnmb,  X.tropicalis
glycoprotein (transmembrane) nmb
NP_001124514.1
587 aa
gpnmb,  D.rerio
glycoprotein (transmembrane) nmb
XP_691804.2
621 aa


Protein Alignments
Protein multiple alignment, pairwise similarity scores and evolutionary distances.

Show Multiple Alignment

Show Pairwise Alignment Scores

Pairwise alignments generated using BLAST
Regenerate Alignments




Publications
Articles associated with genes and sequences of this homology group.

Retinal ganglion cell dendritic atrophy in DBA/2J glaucoma.
Williams PA, et al. PLoS One 8, e72282 (2013).
Genetic dissection of the Gpnmb network in the eye.
Lu H, et al. Invest Ophthalmol Vis Sci 52, 4132-42 (2011).



Conserved Domains
Conserved Domains from CDD found in protein sequences by rpsblast searching.
PKD (cl17457)
  polycystic kidney disease I (PKD) domain; similar to other cell-surface modules, with an IG-like fold; domain probably functions as a ligand binding site in protein-protein or protein-carbohydrate interactions; a single instance of the repeat is presented here. The domain is also found in microbial collagenases and chitinases.



Related Homology Resources
Links to curated and computed homology information found in other databases.
Orthology group for M.musculus Gpnmb includes H.sapiens GPNMB and R.norvegicus Gpnmb.

 

 

 

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