NCBI Logo
GEO Logo
   NCBI > GEO > Accession DisplayHelp Not logged in | LoginHelp
GEO help: Mouse over screen elements for information.
          Go
Series GSE64919 Query DataSets for GSE64919
Status Public on May 13, 2015
Title Genes regulated in EML1 cells expressing the TEL-AML1 oncogene after 5 and 7 days of treatment with IL7 and FLT3 ligand.
Organism Mus musculus
Experiment type Expression profiling by array
Summary The t(12;21) translocation is the most common genetic rearrangement in childhood acute lymphoblastic leukemia (ALL) and gives rise to the TEL-AML1 fusion gene, which functions as a transcription factor.
TEL-AML1 expression in EML1 cells results in an impairment of differentiation along the B-lymphoid lineage.
 
Overall design We analyzed gene expression profiles of EML1 cells after expression of TEL-AML1
 
Contributor(s) Alcalay M
Citation(s) 25893288
Submission date Jan 13, 2015
Last update date Apr 18, 2017
Contact name Myriam Alcalay
E-mail(s) myriam.alcalay@ieo.eu
Organization name European Institute of Oncology
Department Experimental Oncology
Lab Functional Genomics
Street address Via Adamello 16
City Milan
ZIP/Postal code 20139
Country Italy
 
Platforms (1)
GPL11533 [MoGene-1_1-st] Affymetrix Mouse Gene 1.1 ST Array [transcript (gene) version]
Samples (12)
GSM1583299 EML1 infected with the empty pWPI lentiviral vector - rep 1
GSM1583300 EML1 infected with the empty pWPI lentiviral vector - rep 2
GSM1583301 EML1 infected with the empty pWPI lentiviral vector treated with IL7 and FLT3L for 5 days- rep 1
Relations
BioProject PRJNA272512

Download family Format
SOFT formatted family file(s) SOFTHelp
MINiML formatted family file(s) MINiMLHelp
Series Matrix File(s) TXTHelp

Supplementary file Size Download File type/resource
GSE64919_RAW.tar 52.4 Mb (http)(custom) TAR (of CEL)
Raw data provided as supplementary file
Processed data included within Sample table

| NLM | NIH | GEO Help | Disclaimer | Accessibility |
NCBI Home NCBI Search NCBI SiteMap