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Series GSE189533 Query DataSets for GSE189533
Status Public on Dec 02, 2021
Title Cell-Type-Specific Impact of Glucocorticoid Receptor Activation on the Developing Brain: A Cerebral Organoid Study [Wafergen iCell8]
Organism Homo sapiens
Experiment type Expression profiling by high throughput sequencing
Summary These data describe single-cell RNA sequencing in cerebral organoids treated with the glucocorticoid Dexamethasone or with a vehicle control (DMSO) at different culture time-points (Day-30, Day-60 and Day-90).
 
Overall design Single-cell RNA sequencing was performed in cerebral organoids grown in vitro for 30, 60, or 90 days days. Both treated (Dexamethasone 100nM) and untreated (DMSO) organoids were collected immediately after a 12-hour exposure and four biological replicates were employed at each timepoint. Randomization was performed in advance of library preparations.
 
Contributor(s) Cruceanu C, Bider E, Dony L, Roeh S
Citation(s) 34698522
Submission date Nov 24, 2021
Last update date Dec 04, 2021
Contact name Elisabeth B Binder
Organization name Max Planck Institute of Psychiatry
Street address Kraepelinstr. 2-10
City Munich
ZIP/Postal code 80804
Country Germany
 
Platforms (1)
GPL20301 Illumina HiSeq 4000 (Homo sapiens)
Samples (12)
GSM5703291 Organoid_day_30_Dex_Veh_rep1
GSM5703292 Organoid_day_30_Dex_Veh_rep2
GSM5703293 Organoid_day_30_Dex_Veh_rep3
This SubSeries is part of SuperSeries:
GSE189535 Cell-Type-Specific Impact of Glucocorticoid Receptor Activation on the Developing Brain: A Cerebral Organoid Study
Relations
BioProject PRJNA783339
SRA SRP347707

Download family Format
SOFT formatted family file(s) SOFTHelp
MINiML formatted family file(s) MINiMLHelp
Series Matrix File(s) TXTHelp

Supplementary file Size Download File type/resource
GSE189533_RAW.tar 78.8 Mb (http)(custom) TAR (of CSV, TSV)
SRA Run SelectorHelp
Raw data are available in SRA
Processed data provided as supplementary file

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