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Series GSE189080 Query DataSets for GSE189080
Status Public on Nov 30, 2021
Title Differential Expression Profile of MicroRNAs and Tight Junction in Lung Tissue of Rat with Mitomycin-C Induced Pulmonary Veno-Occlusive Disease
Organism Rattus norvegicus
Experiment type Non-coding RNA profiling by high throughput sequencing
Summary Pulmonary veno-occlusive disease (PVOD) is characterized by increased pulmonary vascular resistance. Currently, there is a lack of effective treatment. It is of great significance to explore molecular targets for treatment of the disease. This study investigated the differentially expressed profile of miRNAs and tight junction in the lung tissue of rats with mitomycin-C induced PVOD.
Overall design Fourteen 8-week-old male SD rats were purchased from the SJA Lab Animals Corporation (Hunan, China) and were divided into two groups: the control group (Nā€‰=ā€‰4 rats per group) and the PVOD group (Nā€‰=ā€‰10 rats per group).
Contributor(s) Chen P, Wu S, Chen Y, Zhang Y
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Submission date Nov 18, 2021
Last update date Nov 30, 2021
Contact name Qing Song
Organization name Central South University
Street address Renmin Road 139
City Hunan
ZIP/Postal code 410000
Country China
Platforms (1)
GPL25029 NextSeq 550 (Rattus norvegicus)
Samples (6)
GSM5694321 Lung tissues 1
GSM5694322 Lung tissues 2
GSM5694323 Lung tissues 3
BioProject PRJNA781468
SRA SRP346717

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Supplementary file Size Download File type/resource
GSE189080_RPM.txt.gz 10.6 Kb (ftp)(http) TXT
GSE189080_counts.txt.gz 8.9 Kb (ftp)(http) TXT
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