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Series GSE186005 Query DataSets for GSE186005
Status Public on Oct 20, 2021
Title Klf5 confers embryonic and extra-embryonic bi-potential cell fate in early blastomeres and embryonic stem cells
Organism Mus musculus
Experiment type Expression profiling by high throughput sequencing
Summary This study examines the transcriptomes of embryonic stem cells following overexpression of Klf5. Additionally, this study examines the transcripomes of single embryos either treated with scramble siRNA or siRNA targeting Klf5.
 
Overall design Bulk RNA-seq was performed on mESCs overexpressing Klf5 or GFP as a control. Single embryo RNA-seq was performed on single embryos injected with either a scramble control siRNA, or an siRNA specific to Klf5
 
Contributor(s) Cattoglio C, Kinisu M, He L
Citation(s) 34758315
Submission date Oct 15, 2021
Last update date Jan 19, 2022
Contact name Martin Kinisu
E-mail(s) kinism@berkeley.edu
Phone 2068832373
Organization name University of California Berkely
Department MCB
Lab He Lab
Street address 300C Li Ka Shing Building
City Berkeley
State/province California
ZIP/Postal code 94709
Country USA
 
Platforms (1)
GPL21103 Illumina HiSeq 4000 (Mus musculus)
Samples (20)
GSM5628770 Control, replicate 1
GSM5628771 Control, replicate 2
GSM5628772 Klf5 OE, replicate 1
Relations
BioProject PRJNA771686
SRA SRP341620

Download family Format
SOFT formatted family file(s) SOFTHelp
MINiML formatted family file(s) MINiMLHelp
Series Matrix File(s) TXTHelp

Supplementary file Size Download File type/resource
GSE186005_Klf5KD_counts_final.txt.gz 1.0 Mb (ftp)(http) TXT
GSE186005_Klf5OE_counts_final.txt.gz 457.5 Kb (ftp)(http) TXT
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Raw data are available in SRA
Processed data are available on Series record

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