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Series GSE185952 Query DataSets for GSE185952
Status Public on Oct 15, 2021
Title For lncRNA, circRNA and mRNA sequencing of thyroid-associated ophthalmopathy patients and normal people
Organism Homo sapiens
Experiment type Expression profiling by array
Non-coding RNA profiling by array
Summary We identified the differentially expressed mRNAs and lncRNAs/circRNAs of the case group and the control group through high-throughput sequencing technology, performed a functional enrichment analysis of the differentially expressed genes, and used protein-protein interaction (PPI) analysis to identify the hub genes.
A novel ceRNA network was successfully established, and the network components may serve as promising diagnostic biomarkers or therapeutic targets for thyroid-associated ophthalmopathy in the future.
 
Overall design Orbital adipose/connective tissue was obtained from 3 thyroid-associated ophthalmopathy patients with no history of thyroid disease, inflammatory disease, autoimmune disease, or orbital disease. All the thyroid-associated ophthalmopathy patients underwent orbital decompression for proptosis correction, and control subjects underwent cosmetic upper and lower blepharoplasty. The 3 control groups were obtained from the tissue remains of healthy people after plastic surgery.
 
Contributor(s) Yue Z, Tong F
Citation(s) 34976024
Submission date Oct 14, 2021
Last update date Jan 10, 2022
Contact name Zifan Yue
E-mail(s) y459016247@126.com
Phone 15821673019
Organization name Shanghai Changzheng Hospital
Department Ophthalmology
Street address No. 415 Fengyang Road, Hangpu District
City Shanghai
ZIP/Postal code 200001
Country China
 
Platforms (1)
GPL30862 Agilent-086360 Shbio Human (4*180K) array
Samples (6)
GSM5627753 Orbital adipose/connective tissue_excised_rep1
GSM5627754 Orbital adipose/connective tissue_excised_rep2
GSM5627755 Orbital adipose/connective tissue_excised_rep3
Relations
BioProject PRJNA771460

Download family Format
SOFT formatted family file(s) SOFTHelp
MINiML formatted family file(s) MINiMLHelp
Series Matrix File(s) TXTHelp

Supplementary file Size Download File type/resource
GSE185952_Normalized_Data.txt.gz 16.8 Mb (ftp)(http) TXT
GSE185952_RAW.tar 147.3 Mb (http)(custom) TAR (of TXT)
Raw data provided as supplementary file
Processed data included within Sample table
Processed data are available on Series record

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