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    Manf mesencephalic astrocyte-derived neurotrophic factor [ Mus musculus (house mouse) ]

    Gene ID: 74840, updated on 3-Oct-2021

    Summary

    Official Symbol
    Manfprovided by MGI
    Official Full Name
    mesencephalic astrocyte-derived neurotrophic factorprovided by MGI
    Primary source
    MGI:MGI:1922090
    See related
    Ensembl:ENSMUSG00000032575
    Gene type
    protein coding
    RefSeq status
    VALIDATED
    Organism
    Mus musculus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
    Also known as
    Arm; Armet; D17914; AA407711; AA408789; AA673178; D18Mgi17; 3230402M22Rik
    Expression
    Ubiquitous expression in placenta adult (RPKM 52.6), testis adult (RPKM 26.4) and 26 other tissues See more
    Orthologs
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    Genomic context

    See Manf in Genome Data Viewer
    Location:
    9 F1; 9 57.98 cM
    Exon count:
    4
    Annotation release Status Assembly Chr Location
    109 current GRCm39 (GCF_000001635.27) 9 NC_000075.7 (106765952..106769137, complement)
    108.20200622 previous assembly GRCm38.p6 (GCF_000001635.26) 9 NC_000075.6 (106888753..106891938, complement)
    Build 37.2 previous assembly MGSCv37 (GCF_000001635.18) 9 NC_000075.5 (106789746..106794269, complement)

    Chromosome 9 - NC_000075.7Genomic Context describing neighboring genes Neighboring gene RAD54 like 2 (S. cerevisiae) Neighboring gene DDB1 and CUL4 associated factor 1 Neighboring gene RNA binding motif protein 15B Neighboring gene dedicator of cyto-kinesis 3 Neighboring gene predicted gene, 18542 Neighboring gene pleckstrin homology domain-containing, family A (phosphoinositide binding specific) member 3 pseudogene

    Genomic regions, transcripts, and products

    Expression

    • Project title: Mouse ENCODE transcriptome data
    • Description: RNA profiling data sets generated by the Mouse ENCODE project.
    • BioProject: PRJNA66167
    • Publication: PMID 25409824
    • Analysis date: n/a

    Bibliography

    GeneRIFs: Gene References Into Functions

    What's a GeneRIF?

    Variation

    Alleles

    Alleles of this type are documented at Mouse Genome Informatics  (MGI)

    Interactions

    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

    Markers

    Homology

    Gene Ontology Provided by MGI

    Function Evidence Code Pubs
    enables growth factor activity IEA
    Inferred from Electronic Annotation
    more info
     
    enables lipid binding IEA
    Inferred from Electronic Annotation
    more info
     
    enables sulfatide binding ISO
    Inferred from Sequence Orthology
    more info
     
    Component Evidence Code Pubs
    is_active_in endoplasmic reticulum IBA
    Inferred from Biological aspect of Ancestor
    more info
    PubMed 
    colocalizes_with endoplasmic reticulum ISO
    Inferred from Sequence Orthology
    more info
     
    located_in endoplasmic reticulum lumen ISO
    Inferred from Sequence Orthology
    more info
     
    located_in extracellular region IEA
    Inferred from Electronic Annotation
    more info
     
    is_active_in extracellular space IBA
    Inferred from Biological aspect of Ancestor
    more info
    PubMed 
    located_in extracellular space ISO
    Inferred from Sequence Orthology
    more info
     
    located_in perinuclear region of cytoplasm ISO
    Inferred from Sequence Orthology
    more info
     
    located_in sarcoplasmic reticulum IEA
    Inferred from Electronic Annotation
    more info
     

    General protein information

    Preferred Names
    mesencephalic astrocyte-derived neurotrophic factor
    Names
    arginine-rich protein
    arginine-rich, mutated in early stage tumors

    NCBI Reference Sequences (RefSeq)

    NEW Try the new Transcript table

    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_029103.4NP_083379.2  mesencephalic astrocyte-derived neurotrophic factor precursor

      See identical proteins and their annotated locations for NP_083379.2

      Status: VALIDATED

      Source sequence(s)
      AK131997
      Consensus CDS
      CCDS23486.1
      UniProtKB/TrEMBL
      Q3TMX5
      Related
      ENSMUSP00000124562.2, ENSMUST00000159283.8
      Conserved Domains (1) summary
      pfam10208
      Location:26170
      Armet; Degradation arginine-rich protein for mis-folding

    RefSeqs of Annotated Genomes: Mus musculus Annotation Release 109 details...Open this link in a new tab

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCm39 C57BL/6J

    Genomic

    1. NC_000075.7 Reference GRCm39 C57BL/6J

      Range
      106765952..106769137 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)
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