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    Ms4a6c membrane-spanning 4-domains, subfamily A, member 6C [ Mus musculus (house mouse) ]

    Gene ID: 73656, updated on 25-Nov-2021

    Summary

    Official Symbol
    Ms4a6cprovided by MGI
    Official Full Name
    membrane-spanning 4-domains, subfamily A, member 6Cprovided by MGI
    Primary source
    MGI:MGI:2385644
    See related
    Ensembl:ENSMUSG00000079419
    Gene type
    protein coding
    RefSeq status
    VALIDATED
    Organism
    Mus musculus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
    Also known as
    2200009H22Rik; 2210417N07Rik
    Expression
    Broad expression in spleen adult (RPKM 3.1), mammary gland adult (RPKM 1.9) and 20 other tissues See more
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    Genomic context

    See Ms4a6c in Genome Data Viewer
    Location:
    19; 19 A
    Exon count:
    10
    Annotation release Status Assembly Chr Location
    109 current GRCm39 (GCF_000001635.27) 19 NC_000085.7 (11446718..11464433)
    108.20200622 previous assembly GRCm38.p6 (GCF_000001635.26) 19 NC_000085.6 (11469353..11487182)
    Build 37.2 previous assembly MGSCv37 (GCF_000001635.18) 19 NC_000085.5 (11543858..11556687)

    Chromosome 19 - NC_000085.7Genomic Context describing neighboring genes Neighboring gene heat shock protein 90, alpha (cytosolic), class A member 1 pseudogene Neighboring gene membrane-spanning 4-domains, subfamily A, member 4B Neighboring gene expressed sequence BE692007 Neighboring gene predicted gene 8369 Neighboring gene membrane-spanning 4-domains, subfamily A, member 6B

    Genomic regions, transcripts, and products

    Expression

    • Project title: Mouse ENCODE transcriptome data
    • Description: RNA profiling data sets generated by the Mouse ENCODE project.
    • BioProject: PRJNA66167
    • Publication: PMID 25409824
    • Analysis date: n/a

    Variation

    Alleles

    Alleles of this type are documented at Mouse Genome Informatics  (MGI)

    General gene information

    Gene Ontology Provided by MGI

    Process Evidence Code Pubs
    involved_in cell surface receptor signaling pathway IBA
    Inferred from Biological aspect of Ancestor
    more info
    PubMed 
    Component Evidence Code Pubs
    located_in integral component of membrane IEA
    Inferred from Electronic Annotation
    more info
     
    located_in membrane IEA
    Inferred from Electronic Annotation
    more info
     
    is_active_in plasma membrane IBA
    Inferred from Biological aspect of Ancestor
    more info
    PubMed 
    is_active_in trans-Golgi network IBA
    Inferred from Biological aspect of Ancestor
    more info
    PubMed 
    located_in trans-Golgi network ISO
    Inferred from Sequence Orthology
    more info
     

    General protein information

    Preferred Names
    membrane-spanning 4-domains subfamily A member 6C

    NCBI Reference Sequences (RefSeq)

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    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001166376.1NP_001159848.1  membrane-spanning 4-domains subfamily A member 6C isoform 2

      See identical proteins and their annotated locations for NP_001159848.1

      Status: VALIDATED

      Description
      Transcript Variant: This variant (2) has multiple differences in the presence and absence of exons at its 3' end, compared to variant 1. These differences produce a unique 3' coding region and 3' UTR, compared to variant 1. The encoded protein (isoform 2) is shorter than isoform 1.
      Source sequence(s)
      BC062247, BY164174
      UniProtKB/Swiss-Prot
      Q99N08
      UniProtKB/TrEMBL
      Q6P6F8
      Related
      ENSMUST00000187462.2
      Conserved Domains (1) summary
      pfam04103
      Location:4795
      CD20; CD20-like family
    2. NM_028595.4NP_082871.2  membrane-spanning 4-domains subfamily A member 6C isoform 1

      See identical proteins and their annotated locations for NP_082871.2

      Status: VALIDATED

      Description
      Transcript Variant: This variant (1) represents the longer transcript and encodes the longer isoform (1).
      Source sequence(s)
      AK150397, AK152258, BY164174, BY691481
      Consensus CDS
      CCDS50395.1
      UniProtKB/Swiss-Prot
      Q99N08
      Related
      ENSMUSP00000132425.2, ENSMUST00000165310.3
      Conserved Domains (1) summary
      pfam04103
      Location:47207
      CD20; CD20-like family

    RefSeqs of Annotated Genomes: Mus musculus Annotation Release 109 details...Open this link in a new tab

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCm39 C57BL/6J

    Genomic

    1. NC_000085.7 Reference GRCm39 C57BL/6J

      Range
      11446718..11464433
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_006527381.5XP_006527444.1  membrane-spanning 4-domains subfamily A member 6C isoform X1

      Conserved Domains (1) summary
      pfam04103
      Location:50207
      CD20; CD20-like family

    RNA

    1. XR_877690.3 RNA Sequence

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